Results 21 to 30 of about 5,582 (218)
Advanced Science, 2023 Positioned within the eye, the lens supports vision by transmitting and focusing light onto the retina. As an adaptive glassy material, the lens is constituted primarily by densely‐packed, polydisperse crystallin proteins that organize to resist ...
Michael R. Bergman +4 more
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Crystalline Chlorocruorin [PDF]
Nature, 1933 Abstract Chlorocruorin is a respiratory pigment, closely allied to hæmoglobin, which occurs only in the blood of certain polychæte worms (Fox, 1926, 1932, 1933). We have now succeeded in crystallizing chlorocruorin. A description is given below of the method of crystallization, of the nature of the crystals, of the absorption spectrum
Jean Roche, Harold Munro Fox
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αA-crystallin peptide SDRDKFVIFLDVKHF accumulating in aging lens impairs the function of α-crystallin and induces lens protein aggregation. [PDF]
PLoS ONE, 2011 The eye lens is composed of fiber cells that are filled with α-, β- and γ-crystallins. The primary function of crystallins is to maintain the clarity of the lens through ordered interactions as well as through the chaperone-like function of α-crystallin.
Puttur Santhoshkumar +2 more
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Ubiquitous lens α-, β-, and γ-crystallins accumulate in anuran cornea as corneal crystallins [PDF]
, 2007 Corneal epithelium is known to have high levels of some metabolic enzymes such as aldehyde dehydrogenase in mammals, gelsolin in zebrafish, and α-enolase in several species.
Aggrawal, Ramesh K. +6 more
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The Crystalline Nephropathies [PDF]
Kidney International Reports, 2021 Crystalline nephropathies are a unique form of kidney disease characterized by the histologic finding of intrarenal crystal deposition. The intrinsic nature of some molecules and ions combined with a favorable tubular fluid physiology leads to crystal precipitation and deposition within the tubular lumens.
Perazella, Mark A., Herlitz, Leal C.
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Association of two crystallins in macromolecular crowding. [PDF]
, 2016 Sketch of two crystallins as reactants polymerising into a dimer as product for (a) thermodynamic perturbation model (TPM), where blue spheres represent crystallins with isotropic intermolecular attraction, and (b) chemical binding model (CBM), where ...
Fan Song (110016) +3 more
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Strain-independent increases of crystallin proteins in the retina of type 1 diabetic rats. [PDF]
PLoS ONE, 2013 Diabetic retinopathy is the leading cause of vision loss in working-age individuals in the United States and is expected to continue growing with the increased prevalence of diabetes. Streptozotocin-induced hyperglycemia in rats is the most commonly used
Erich A Heise +5 more
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Data in Brief, 2020 The interaction of αA- and αB-crystallins with Cu2+ ion modulates their structure and chaperone-like activity which is important for lens transparency. Theoretical analysis of the dependences of fluorescence intensity of native αA- and αB-crystallins and
Maryam Ghahramani +4 more
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Science, 1929 A method is described for the preparation of a crystalline protein from commercial pepsin preparations which has powerful peptic activity. The composition, optical activity, and proteolytic activity of this protein remain constant through seven successive crystallizations.
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Concurrence of Danish dementia and cataract: insights from the interactions of dementia associated peptides with eye lens alpha-crystallin. [PDF]
PLoS ONE, 2008 Familial Danish Dementia (FDD) is an autosomal disease, which is distinguished by gradual loss of vision, deafness, progressive ataxia and dementia. Cataract is the first manifestation of the disease.
Ira Surolia +5 more
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