Results 51 to 60 of about 15,579 (272)

Comparative Analysis of Heat Exposure‐Induced Molecular Changes in Two Turtle Species with Contrasting Thermal Adaptations

open access: yesIntegrative Zoology, EarlyView.
Protein processing in the endoplasmic reticulum is highlighted in response to heat stress in Platysternon megacephalum. Under heat stress, the up‐regulation of genes such as CHOP in protein processing in the endoplasmic reticulum pathway, along with the suppression of energy and lipid metabolism and the up‐regulation of JARID2 expression, leads to ...
Jian Hong   +7 more
wiley   +1 more source

Functional Role of γ-Crystallin N in the Auditory Hindbrain. [PDF]

open access: yesPLoS ONE, 2016
γ-crystallins are major components of the vertebrate lens but show expression in other tissues as well. Their extralenticular functions remain so far unclear.
Heiner Hartwich   +5 more
doaj   +1 more source

Transcriptional profiling of single fiber cells in a transgenic paradigm of an inherited childhood cataract reveals absence of molecular heterogeneity. [PDF]

open access: yes, 2019
Our recent single-cell transcriptomic analysis has demonstrated that heterogeneous transcriptional activity attends molecular transition from the nascent to terminally differentiated fiber cells in the developing mouse lens.
Bhat, Suraj P   +6 more
core  

Anterior chamber flare and central macular thickness after trabeculectomy versus after phacoemulsification

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To compare the inflammatory response in the eye after trabeculectomy to after phacoemulsification, focusing on anterior chamber flare (AC flare) and central macular thickness (CMT). Methods Data from 436 participants in two randomized controlled trials were analysed.
Yasmeen Ahmed   +5 more
wiley   +1 more source

Crystallins are regulated biomarkers for monitoring topical therapy of glaucomatous optic neuropathy. [PDF]

open access: yesPLoS ONE, 2013
Optic nerve atrophy caused by abnormal intraocular pressure (IOP) remains the most common cause of irreversible loss of vision worldwide. The aim of this study was to determine whether topically applied IOP-lowering eye drugs affect retinal ganglion ...
Verena Prokosch   +2 more
doaj   +1 more source

Tau-crystallin/alpha-enolase: one gene encodes both an enzyme and a lens structural protein. [PDF]

open access: yes, 1988
tau-Crystallin has been a major component of the cellular lenses of species throughout vertebrate evolution, from lamprey to birds. Immunofluorescence analysis of the embryonic turtle lens, using antiserum to lamprey tau-crystallin showed that the ...
de Jong, WW   +6 more
core  

Potential of human γD-crystallin for hair damage repair : insights into the mechanical properties and biocompatibility [PDF]

open access: yes, 2013
The objective of this work was to develop a new strategy to physically ‘repair’ chemically damaged hair. Hence the human eye γD-crystallin, a protein from the superfamily characterized structurally by the Greek key motif, was studied.
Andersson   +25 more
core   +1 more source

Radiopaque Crystalline, Non-Crystalline and Nanostructured Bioceramics

open access: yesMaterials, 2022
Radiopacity is sometimes an essential characteristic of biomaterials that can help clinicians perform follow-ups during pre- and post-interventional radiological imaging. Due to their chemical composition and structure, most bioceramics are inherently radiopaque but can still be doped/mixed with radiopacifiers to increase their visualization during or ...
Maziar Montazerian   +10 more
openaire   +3 more sources

In vitro interactions of histones and α-crystallin

open access: yesBiochemistry and Biophysics Reports, 2018
The aggregation of crystallins in lenses is associated with cataract formation. We previously reported that mutant crystallins are associated with an increased abundance of histones in knock-in and knockout mouse models.
Paul D. Hamilton, Usha P. Andley
doaj   +1 more source

Comparison of the Lens Protein Profiles of Three Species of Ozark Salamanders [PDF]

open access: yes, 1979
The vertebrate lens has a high protein content (35%), 80-90% of which is composed of the soluble, lens-specific structural proteins, the crystallins. The lens protein profiles of urodelan species have been found to be qualitatively distinct.
Britton, James M.
core   +2 more sources

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