Results 71 to 80 of about 8,769 (230)
Identification of subunit-subunit interaction sites in αA-WT crystallin and mutant αA-G98R crystallin using isotope-labeled cross-linker and mass spectrometry. [PDF]
PLoS ONE, 2013 Cataract is characterized by progressive protein aggregation and loss of vision. α-Crystallins are the major proteins in the lens responsible for maintaining transparency.
Rama Kannan +3 more
doaj +1 more source
Effect of Substrate Composition and Alignment on Corneal Cell Phenotype [PDF]
, 2011 Corneal blindness is a significant problem treated primarily by corneal transplants. Donor tissue supply is low, creating a growing need for an alternative.
Phu, Donna, \u2709 +4 more
core +3 more sources
The FEBS Journal, EarlyView.Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf +7 more
wiley +1 more source
Redox Activity of the Mini-αA-crystallin–Cu(II) Complex and Its Biological Relevance
International Journal of Electrochemical Science, 2015 Cu(II) has been known to be a redox-active metal whose complexes with proteins/peptides have been linked to oxidative stress in many diseases. Oxidative stress and Cu(II) are also known to induce the expression of the small heat shock proteins α ...
Yanping Gao, Yanyan Wang, Wenxia Liu
doaj +1 more source
From A. rhizogenes RolD to Plant P5CS: Exploiting Proline to Control Plant Development [PDF]
, 2018 The capability of the soil bacterium Agrobacterium rhizogenes to reprogram plant development and induce adventitious hairy roots relies on the expression of a few root-inducing genes (rol A, B, C and D), which can be transferred from large virulence ...
Costantino, Paolo +2 more
core +1 more source
Journal of Integrative Plant Biology, EarlyView.Abscisic acid signaling homeostasis is essential for seed storability. The molecular chaperone OsCPN10a enhances rice seed storability by forming a trimeric chaperone complex with OsCPN20‐OsHSP60‐3B that attenuates abscisic acid signaling via direct interaction with OsPYL10‐OsABIL1, thereby maintaining starch integrity and offering a promising target ...
Sufeng Liao +13 more
wiley +1 more source
iScience, 2018 Summary: The developing eye lens presents an exceptional paradigm for spatial transcriptomics. It is composed of highly organized long, slender transparent fiber cells, which differentiate from the edges of the anterior epithelium of the lens (equator ...
Rajendra K. Gangalum +6 more
doaj +1 more source
Ca2+ binding enhanced mechanical stability of an archaeal crystallin. [PDF]
PLoS ONE, 2014 Structural topology plays an important role in protein mechanical stability. Proteins with β-sandwich topology consisting of Greek key structural motifs, for example, I27 of muscle titin and (10)FNIII of fibronectin, are mechanically resistant as shown ...
Venkatraman Ramanujam +2 more
doaj +1 more source
Zoologica Scripta, EarlyView.ABSTRACT Understanding Neotropical megadiversity remains challenging due to fundamental taxonomic issues, including identifying and describing cryptic species and their distribution, and the limited knowledge of key factors driving biological diversification. Such challenges are especially prominent in diverse clades with high levels of cryptic species,
Felipe Camurugi +10 more
wiley +1 more source
CRYSTALLINE RIBONUCLEASE [PDF]
Journal of General Physiology, 1940 1. A crystalline enzyme capable of digesting yeast nucleic acid has been isolated from fresh beef pancreas. 2. The enzyme called "ribonuclease" is a soluble protein of albumin type. Its molecular weight is about 15,000. Its isoelectric point is in the region of pH 8.0. 3.
openaire +2 more sources