Results 81 to 90 of about 15,579 (272)

Structural integrity of the Greek key motif in βγ-crystallins is vital for central eye lens transparency. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: We highlight an unrecognized physiological role for the Greek key motif, an evolutionarily conserved super-secondary structural topology of the βγ-crystallins.
Venkata Pulla Rao Vendra   +5 more
doaj   +1 more source

CRYSTALLINE RIBONUCLEASE [PDF]

open access: yesJournal of General Physiology, 1940
1. A crystalline enzyme capable of digesting yeast nucleic acid has been isolated from fresh beef pancreas. 2. The enzyme called "ribonuclease" is a soluble protein of albumin type. Its molecular weight is about 15,000. Its isoelectric point is in the region of pH 8.0. 3.
openaire   +2 more sources

Patients Suffering From Post‐COVID‐19 Syndrome Feature Enhanced Antibody Reactivity Towards Specific Linear Epitopes Within EBV EBNA1

open access: yesScandinavian Journal of Immunology, Volume 103, Issue 1, January 2026.
Compared to convalescent individuals, post‐COVID‐19 patients showed increased IgG antibody reactivity in plasma to both a specific central region (amino acids 405–419) and glycine–alanine repeat sequences of EBV EBNA1. The sequences of the central region differ from those associated with molecular mimicry in multiple sclerosis patients.
Peter Lorenz   +7 more
wiley   +1 more source

A novel non-lens betagamma-crystallin and trefoil factor complex from amphibian skin and its functional implications. [PDF]

open access: yesPLoS ONE, 2008
In vertebrates, non-lens betagamma-crystallins are widely expressed in various tissues, but their functions are unknown. The molecular mechanisms of trefoil factors, initiators of mucosal healing and being greatly involved in tumorigenesis, have remained
Shu-Bai Liu   +6 more
doaj   +1 more source

Binding of Hg(I) and Hg(II) Ions to Amyloid‐Beta (Aβ) Peptide Variants Affect their Structure and Aggregation

open access: yesChemBioChem, Volume 26, Issue 24, December 11, 2025.
Mercury (Hg) is a possible risk factor for Alzheimer's disease, where neuronal death is related to amyloid brain plaques containing aggregated amyloid‐β (Aβ) peptides. We show that equimolar Hg(I) or Hg(II) ions inhibit normal Aβ aggregation. Hg(II) binds Aβ(1–40) with an apparent binding affinity 28 ± 8 μM.
Elina Berntsson   +7 more
wiley   +1 more source

Development of an immunoanalytical method for the detection of β- and γ- Crystallins and anti-crystallin antibodies. A molecular biomarker for cataract

open access: yesIndian Journal of Ophthalmology, 2002
Purpose: To develop and evaluate an immunoanalytical method for the detection of β - and g-crystallins and anti-crystallin antibodies. Materials and Methods: Beta and g-crystallins isolated from rat lens were used as immunogens to raise ...
Nayak Sujatha   +2 more
doaj  

UV-radiation Induced Disruption of Dry-Cavities in Human γD-crystallin Results in Decreased Stability and Faster Unfolding [PDF]

open access: yes, 2012
Age-onset cataracts are believed to be expedited by the accumulation of UV-damaged human γD-crystallins in the eye lens. Here we show with molecular dynamics simulations that the stability of γD-crystallin is greatly reduced by the conversion of ...
Huynh, Tien   +4 more
core   +2 more sources

A 17‐year‐old male with chronic epilepsy status post remote functional hemispherectomy

open access: yes
Brain Pathology, EarlyView.
Claire Voyles   +3 more
wiley   +1 more source

Structural and Electrical Behavior of Swift Heavy Ion Irradiated Hafnium Oxide Polymorphs in Ferroelectric and Resistive Memories

open access: yesAdvanced Electronic Materials, Volume 11, Issue 21, December 17, 2025.
This study investigates the irradiation resistance of different HfO2‐x stacks to swift heavy ions with different energies. The results demonstrate that Ca‐ion irradiation has a negligible effect on the crystallinity and switching properties of the functional layers.
Philipp Schreyer   +12 more
wiley   +1 more source

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