Results 81 to 90 of about 15,579 (272)
Structural integrity of the Greek key motif in βγ-crystallins is vital for central eye lens transparency. [PDF]
BACKGROUND: We highlight an unrecognized physiological role for the Greek key motif, an evolutionarily conserved super-secondary structural topology of the βγ-crystallins.
Venkata Pulla Rao Vendra +5 more
doaj +1 more source
CRYSTALLINE RIBONUCLEASE [PDF]
1. A crystalline enzyme capable of digesting yeast nucleic acid has been isolated from fresh beef pancreas. 2. The enzyme called "ribonuclease" is a soluble protein of albumin type. Its molecular weight is about 15,000. Its isoelectric point is in the region of pH 8.0. 3.
openaire +2 more sources
Compared to convalescent individuals, post‐COVID‐19 patients showed increased IgG antibody reactivity in plasma to both a specific central region (amino acids 405–419) and glycine–alanine repeat sequences of EBV EBNA1. The sequences of the central region differ from those associated with molecular mimicry in multiple sclerosis patients.
Peter Lorenz +7 more
wiley +1 more source
A novel non-lens betagamma-crystallin and trefoil factor complex from amphibian skin and its functional implications. [PDF]
In vertebrates, non-lens betagamma-crystallins are widely expressed in various tissues, but their functions are unknown. The molecular mechanisms of trefoil factors, initiators of mucosal healing and being greatly involved in tumorigenesis, have remained
Shu-Bai Liu +6 more
doaj +1 more source
Mercury (Hg) is a possible risk factor for Alzheimer's disease, where neuronal death is related to amyloid brain plaques containing aggregated amyloid‐β (Aβ) peptides. We show that equimolar Hg(I) or Hg(II) ions inhibit normal Aβ aggregation. Hg(II) binds Aβ(1–40) with an apparent binding affinity 28 ± 8 μM.
Elina Berntsson +7 more
wiley +1 more source
Purpose: To develop and evaluate an immunoanalytical method for the detection of β - and g-crystallins and anti-crystallin antibodies. Materials and Methods: Beta and g-crystallins isolated from rat lens were used as immunogens to raise ...
Nayak Sujatha +2 more
doaj
UV-radiation Induced Disruption of Dry-Cavities in Human γD-crystallin Results in Decreased Stability and Faster Unfolding [PDF]
Age-onset cataracts are believed to be expedited by the accumulation of UV-damaged human γD-crystallins in the eye lens. Here we show with molecular dynamics simulations that the stability of γD-crystallin is greatly reduced by the conversion of ...
Huynh, Tien +4 more
core +2 more sources
Loss of αA or αB-Crystallin Accelerates Photoreceptor Cell Death in a Mouse Model of P23H Autosomal Dominant Retinitis Pigmentosa [PDF]
Tiantian Wang +4 more
openalex +1 more source
A 17‐year‐old male with chronic epilepsy status post remote functional hemispherectomy
Brain Pathology, EarlyView.
Claire Voyles +3 more
wiley +1 more source
This study investigates the irradiation resistance of different HfO2‐x stacks to swift heavy ions with different energies. The results demonstrate that Ca‐ion irradiation has a negligible effect on the crystallinity and switching properties of the functional layers.
Philipp Schreyer +12 more
wiley +1 more source

