Results 201 to 210 of about 86,469 (244)
Angewandte Chemie International Edition, Accepted Article.CD59 is an immunomodulatory cell surface receptor associated with human disease. Despite its importance in complement regulation and bacterial pathogenesis, CD59 remains a challenging therapeutic target. Research to date has focused on antibody or protein‐based strategies.
Edward William Tate +12 more
wiley +1 more source
Angewandte Chemie International Edition, Accepted Article.We present the first reductive kinetic resolution of racemic 2H‐azirines to prepare optically enriched N‐H aziridine‐2‐carboxylates, which are bench stable and easily diversifiable building blocks, concomitantly with the corresponding enantiomerically enriched 2H‐azirines. The N‐H aziridines were obtained with excellent diastereoselectivity (>20:1) and
Yinuo Zheng +3 more
wiley +1 more source
Angewandte Chemie International Edition, EarlyView.Progressively enhanced oxygen evolution is achieved by self‐optimization of cobalt tungsten oxide deposited on lab‐synthesized copper oxide substrate. Experimental data proved dynamic compositional / structural evolution while theoretical calculation revealed active site adaptation.
Christean Nickel +16 more
wiley +1 more source
An Engineered Biocatalyst for Enantioselective Hydrazone Reduction
Angewandte Chemie International Edition, Accepted Article.Enantioselective reduction of hydrazones provides a convergent and versatile route to synthesize hydrazine‐containing motifs that are commonly found in pharmaceuticals and agrochemicals. However current methods require the use of precious metals, costly chiral ligands and/or forcing reaction conditions. Here, we report the development of a biocatalytic
Anthony P. Green +9 more
wiley +1 more source
Lithium Anionic Dicarbenes or Acetylides: What is in the Name?
Angewandte Chemie International Edition, EarlyView.The two‐fold deprotonation of the C2‐arylated 1,3‐imidazolium salts with nBuLi affords the so‐called lithium anionic dicarbenes Li(ADC). X‐Ray diffraction studies reveal that Li(ADC) exist as lithium acetylides Li(ACT). Exposure of Li(ACT) to CO2 and N2O readily afford ADC‐compounds Li[(ADC)(CO2)2] and Li[(ADC)N2O], respectively.
Arne Merschel +5 more
wiley +1 more source
Angewandte Chemie International Edition, Accepted Article.Phosphodiester groups occur ubiquitously in nature, e.g. in nucleic acids or in cyclic (di‐)nucleotides important for signal transduction. Proteins often use polar or positively charged amino acids to interact with the negatively charged phosphodiester groups via hydrogen bonds and salt bridges.
Jens Wöhnert +5 more
wiley +1 more source
Angewandte Chemie International Edition, Accepted Article.A series of tetrakisimidazolium salts bearing two di(phenylimidazolium)amine groups linked by differently substituted anthracenes has been prepared. These are H4‐1a(PF6)4 (anthracene bridge), H4‐1b(PF6)4 (phenyl‐anthracene‐phenyl bridge), H4‐1c(PF6)4 (anthracene‐phenyl bridge) and H4‐1d(PF6)4 (anthracene‐phenyl‐anthracene bridge). X‐ray crystallography
Guang-Feng Jin +3 more
wiley +1 more source
Decoding Variants of Pyrite, Arsenopyrite and Marcasite Using an Electron Counting Rule
Angewandte Chemie International Edition, Accepted Article.Pyrite, Marcasite and Arsenopyrite are of significant historical and contemporary interest. Compounds adopting these structure types are extensively studied for their crystallographic properties and potential applications in energy storage and conversion.
Dirk Johrendt +2 more
wiley +1 more source