Results 201 to 210 of about 485,962 (354)

Synthesis of (−)‐8a‐epi‐Lentiginosine via Tsuji–Trost Reaction of d‐Glucose‐Derived Allylic Alcohols and Crystal Structure Analysis

open access: yesAsian Journal of Organic Chemistry, EarlyView.
A facile synthetic route to (−)‐8a‐epi‐lentiginosine from d‐glucose using the Pd‐BiPhePhos catalyzed intramolecular Tsuji–Trost reaction of non−derivatized allylic alcohol as a key construction of the hydroxylated pyrrolidine ring is reported. The crystal structure of (−)‐8a‐epi‐lentiginosne showed the envelope conformation of the five‐membered ring ...
Sunisa Akkarasamiyo   +3 more
wiley   +1 more source

Synthesis of Benzodithieno[5.5.5.6]Fenestranes: Unexpected Epimerization and Regiochemical Outcomes

open access: yesAsian Journal of Organic Chemistry, EarlyView.
Isomeric [5.5.5.6]fenestranes annulated with one benzene and two thiophene rings are accessible via di‐2‐ and di‐3‐thienylspirane intermediates. The key double cyclization step involves surprising stereoselectivity and regioselectivity. In particular, cis‐di(2‐thienyl)spirane precursors lead to the all‐cis‐fenestrane skeleton by an unexpected acid ...
Björn Bredenkötter   +5 more
wiley   +1 more source

Synthesis and Chiroptical Properties of Chiral Helical Foldamers Based on Highly Fluorescent Dibenzopyrrolo[1,2‐a][1,8]naphthyridines Linked to a Tetraphenylene Core

open access: yesAsian Journal of Organic Chemistry, EarlyView.
Chiral tetraphenylene derivatives possessing helical motifs were developed by linking multiple dibenzopyrrolo[1,2‐a][1,8]naphthyridine units to a tetraphenylene core. These helical motifs adopted helical conformations in solution and exhibited high fluorescence (φ > 0.8).
Kotaro Matsumura   +3 more
wiley   +1 more source

On‐Demand Ligate and Release Strategy Based on Photoclick Reaction in Tandem with Pd‐Mediated Deallylation

open access: yesAngewandte Chemie, EarlyView.
A consecutive, controllable, and revertible new‐to‐nature ligation and cleavage strategy has been rationally devised to selectively visualize and manipulate biomolecules of interest. The photoclick cycloaddition between allenyl phenyl ether motifs and 9,10‐phenanthrenequinone analogues installed a terminal allyl handle at the exocyclic site, thereby ...
Boon Shing Loh   +4 more
wiley   +2 more sources

Brassinin from Brassica campestris L. inhibits colorectal cancer by inducing p62/NRF2/GPX4‐regulated ferroptosis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
BSN suppresses the cell viability of colorectal cancer by inducing GPX4‐regulated ferroptosis. BSN may bind to NRF2 protein to inactivate the NRF2 signaling, inhibiting the expression of p62 and HO‐1. Abstract Background Indole phytoalexins, plant‐derived compounds present in cruciferous vegetables, have demonstrated anticancer properties.
Shi‐Yuan Wen   +5 more
wiley   +1 more source

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