Results 201 to 210 of about 485,962 (354)
Selected Topics in X-ray Crystallography from the Delft X-ray Institutes edited by J. Bouman [PDF]
Anthony J. Wilson
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A facile synthetic route to (−)‐8a‐epi‐lentiginosine from d‐glucose using the Pd‐BiPhePhos catalyzed intramolecular Tsuji–Trost reaction of non−derivatized allylic alcohol as a key construction of the hydroxylated pyrrolidine ring is reported. The crystal structure of (−)‐8a‐epi‐lentiginosne showed the envelope conformation of the five‐membered ring ...
Sunisa Akkarasamiyo+3 more
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Synthesis of Benzodithieno[5.5.5.6]Fenestranes: Unexpected Epimerization and Regiochemical Outcomes
Isomeric [5.5.5.6]fenestranes annulated with one benzene and two thiophene rings are accessible via di‐2‐ and di‐3‐thienylspirane intermediates. The key double cyclization step involves surprising stereoselectivity and regioselectivity. In particular, cis‐di(2‐thienyl)spirane precursors lead to the all‐cis‐fenestrane skeleton by an unexpected acid ...
Björn Bredenkötter+5 more
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Microcrystals in structural biology: small samples, big insights. [PDF]
Oberthür D.
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Chiral tetraphenylene derivatives possessing helical motifs were developed by linking multiple dibenzopyrrolo[1,2‐a][1,8]naphthyridine units to a tetraphenylene core. These helical motifs adopted helical conformations in solution and exhibited high fluorescence (φ > 0.8).
Kotaro Matsumura+3 more
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A consecutive, controllable, and revertible new‐to‐nature ligation and cleavage strategy has been rationally devised to selectively visualize and manipulate biomolecules of interest. The photoclick cycloaddition between allenyl phenyl ether motifs and 9,10‐phenanthrenequinone analogues installed a terminal allyl handle at the exocyclic site, thereby ...
Boon Shing Loh+4 more
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Crystallography at University College, London Dr. Kathleen Lonsdale, F.R.S [PDF]
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BSN suppresses the cell viability of colorectal cancer by inducing GPX4‐regulated ferroptosis. BSN may bind to NRF2 protein to inactivate the NRF2 signaling, inhibiting the expression of p62 and HO‐1. Abstract Background Indole phytoalexins, plant‐derived compounds present in cruciferous vegetables, have demonstrated anticancer properties.
Shi‐Yuan Wen+5 more
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