Results 1 to 10 of about 37,852,591 (164)

Bactericidal Properties of Rod-, Peanut-, and Star-Shaped Gold Nanoparticles Coated with Ceragenin CSA-131 against Multidrug-Resistant Bacterial Strains [PDF]

Pharmaceutics, 2021
Background: The ever-growing number of infections caused by multidrug-resistant (MDR) bacterial strains requires an increased effort to develop new antibiotics.
Sylwia Joanna Chmielewska, Karol Skłodowski, Joanna Depciuch, Piotr Deptuła, Ewelina Piktel, Krzysztof Fiedoruk, Patrycja Kot, Paulina Paprocka, Kamila Fortunka, Tomasz Wollny, Przemysław Wolak, Magdalena Parlinska-Wojtan, Paul B. Savage, Robert Bucki   +13 more
doaj   +6 more sources

NDM-1 Carbapenemase-Producing Enterobacteriaceae Are Highly Susceptible to Ceragenins CSA-13, CSA-44, and CSA-131 [PDF]

Infection and Drug Resistance, 2020
Sylwia Joanna Chmielewska,1 Karol Skłodowski,1 Ewelina Piktel,1 Łukasz Suprewicz,1 Krzysztof Fiedoruk,1 Tamara Daniluk,1 Przemysław Wolak,2 Paul B Savage,3 Robert Bucki1 1Department of Medical Microbiology and Nanobiomedical Engineering, Medical ...
Łukasz Suprewicz, Krzysztof Fiedoruk, Robert Bucki   +2 more
exaly   +9 more sources

Enhanced shear strength of a medical adhesive due to an antimicrobial additive

SN Applied Sciences, 2023
Adhesives play a crucial role in many industries, including medicine, construction, and electronics. In the medical field, additives may be incorporated into adhesives to enhance drug delivery or prevent infection.
Alexander J. Farnsworth, Kayla M. Holland, Aaron L. Zaugg, Fetutasi Pauga, Shane M. Drake, Paul B. Savage, James E. Patterson   +6 more
doaj   +1 more source

Ceragenin-Coated Non-Spherical Gold Nanoparticles as Novel Candidacidal Agents

Pharmaceutics, 2021
Background: Infections caused by Candida spp. have become one of the major causes of morbidity and mortality in immunocompromised patients. Therefore, new effective fungicides are urgently needed, especially due to an escalating resistance crisis ...
Karol Skłodowski, Sylwia Joanna Chmielewska, Joanna Depciuch, Piotr Deptuła, Ewelina Piktel, Tamara Daniluk, Magdalena Zakrzewska, Michał Czarnowski, Mateusz Cieśluk, Bonita Durnaś, Magdalena Parlińska-Wojtan, Paul B. Savage, Robert Bucki   +12 more
doaj   +1 more source

Assessment of Ceragenins in Prevention of Damage to Voice Prostheses Caused by Candida Biofilm Formation

Pathogens, 2021
This study aimed to investigate the potential application of ceragenins (CSAs) as new candidacidal agents to prevent biofilm formation on voice prostheses (VPs).
Jakub Spałek, Tamara Daniluk, Adrian Godlewski, Piotr Deptuła, Urszula Wnorowska, Dominika Ziembicka, Mateusz Cieśluk, Krzysztof Fiedoruk, Michał Ciborowski, Adam Krętowski, Stanisław Góźdź, Bonita Durnaś, Paul B. Savage, Sławomir Okła, Robert Bucki   +14 more
doaj   +1 more source

Candidacidal Activity of Selected Ceragenins and Human Cathelicidin LL-37 in Experimental Settings Mimicking Infection Sites. [PDF]

PLoS ONE, 2016
Fungal infections, especially those caused by antibiotic resistant pathogens, have become a serious public health problem due to the growing number of immunocompromised patients, including those subjected to anticancer treatment or suffering from HIV ...
Bonita Durnaś, Urszula Wnorowska, Katarzyna Pogoda, Piotr Deptuła, Marzena Wątek, Ewelina Piktel, Stanisław Głuszek, Xiaobo Gu, Paul B Savage, Katarzyna Niemirowicz, Robert Bucki   +10 more
doaj   +1 more source

Antimicrobial Activity of Ceragenins against Vancomycin-Susceptible and -Resistant Enterococcus spp.

Pharmaceuticals, 2023
Ceragenins (CSAs) are a new class of antimicrobial agents designed to mimic the activities of endogenous antimicrobial peptides. In this study, the antibacterial activities of various ceragenins (CSA-13, CSA-44, CSA-90, CSA-131, CSA-138, CSA-142, and CSA-
Mayram Hacioglu, Fatima Nur Yilmaz, Ozlem Oyardi, Cagla Bozkurt Guzel, Nese Inan, Paul B. Savage, Sibel Dosler   +6 more
doaj   +1 more source

Effects of Ceragenins and Antimicrobial Peptides on the A549 Cell Line and an In Vitro Co-Culture Model of A549 Cells and Pseudomonas aeruginosa

Pathogens, 2022
Pseudomonas aeruginosa is an important pathogen that can adhere to host tissues and epithelial surfaces, especially during chronic infections such as cystic fibrosis (CF) lung infections.
Ozlem Oyardi, Paul B. Savage, Cagla Bozkurt Guzel   +2 more
doaj   +1 more source

Genetic Structure of Aedes (Stegomyia) albopictus Populations in Russia

Journal of Arthropod-Borne Diseases, 2023
Background: Aedes (Stegomyia) albopictus was found for the first time in 2011 on the Black Sea coast in Russia, and dur­ing 2011–2019, the species expanded over two climate zones Cfa and Csa.
Elena V. Shaikevich, Ludmila Karan, Marina Fedorova   +2 more
doaj   +1 more source

Bactericidal Activity of Ceragenin in Combination with Ceftazidime, Levofloxacin, Co-Trimoxazole, and Colistin against the Opportunistic Pathogen Stenotrophomonas maltophilia

Pathogens, 2022
Background: Stenotrophomonas maltophilia (S. maltophilia) is an emerging opportunistic Gram-negative rod causing nosocomial infections predominantly in immunocompromised patients.
Paulina Paprocka, Angelika Mańkowska, Karol Skłodowski, Grzegorz Król, Tomasz Wollny, Agata Lesiak, Katarzyna Głuszek, Paul B. Savage, Bonita Durnaś, Robert Bucki   +9 more
doaj   +1 more source