Ceragenin CSA-44 as a Means to Control the Formation of the Biofilm on the Surface of Tooth and Composite Fillings [PDF]
Pathogens, 2022 Recurrent oral infections, as manifested by endodontic and periodontal disease, are often caused by Enterococcus faecalis (E. faecalis) and Candida albicans (C. albicans).
Robert Bucki +2 more
exaly +5 more sources
Antibacterial and Antifungal Activities of Poloxamer Micelles Containing Ceragenin CSA-131 on Ciliated Tissues [PDF]
Molecules, 2018 Ceragenins were designed as non-peptide mimics of endogenous antimicrobial peptides, and they display broad-spectrum antibacterial and antifungal activities, including the ability to eradicate established biofilms.
Jordan Coburn +2 more
exaly +5 more sources
Bactericidal Properties of Rod-, Peanut-, and Star-Shaped Gold Nanoparticles Coated With Ceragenin CSA-131 Against Multidrug-Resistant Bacterial Strains [PDF]
Pharmaceutics, 2021 Background: The ever-growing number of infections caused by multidrug-resistant (MDR) bacterial strains requires an increased effort to develop new antibiotics.
Magdalena Parlińska-Wojtan +2 more
exaly +5 more sources
Quantification of Synergistic Effects of Ceragenin CSA-131 Combined With Iron Oxide Magnetic Nanoparticles Against Cancer Cells [PDF]
International Journal of Nanomedicine, 2020 Ewelina Piktel,1 Karolina H Markiewicz,2 Agnieszka Z Wilczewska,2 Tamara Daniluk,1 Sylwia Chmielewska,1 Katarzyna Niemirowicz-Laskowska,1 Joanna Mystkowska,3 Paulina Paprocka,4 Paul B Savage,5 Robert Bucki1,4 1Department of Medical Microbiology and ...
Robert Bucki +2 more
exaly +5 more sources
Ceragenin-Coated Non-Spherical Gold Nanoparticles as Novel Candidacidal Agents [PDF]
Pharmaceutics, 2021 Background: Infections caused by Candida spp. have become one of the major causes of morbidity and mortality in immunocompromised patients. Therefore, new effective fungicides are urgently needed, especially due to an escalating resistance crisis ...
Karol Skłodowski +12 more
doaj +5 more sources
Antimicrobial Growth Promoters Altered the Function but Not the Structure of Enteric Bacterial Communities in Broiler Chicks ± Microbiota Transplantation [PDF]
Animals, 2023 Non-antibiotic alternatives to antimicrobial growth promoters (AGPs) are required, and understanding the mode of action of AGPs may facilitate the development of effective alternatives.
Colten R. Hodak +6 more
doaj +3 more sources
Assessment of Ceragenins in Prevention of Damage to Voice Prostheses Caused by Candida Biofilm Formation [PDF]
Pathogens, 2021 This study aimed to investigate the potential application of ceragenins (CSAs) as new candidacidal agents to prevent biofilm formation on voice prostheses (VPs).
Jakub Spałek +14 more
doaj +3 more sources
In Vitro Bactericidal and Bacteriolytic Activity of Ceragenin CSA-13 Against Planktonic Cultures and Biofilms of Streptococcus pneumoniae and Other Pathogenic Streptococci [PDF]
PLoS ONE, 2014 Ceragenin CSA-13, a cationic steroid, is here reported to show a concentration-dependent bactericidal/bacteriolytic activity against pathogenic streptococci, including multidrug-resistant Streptococcus pneumoniae.
María Esteban-Torres +2 more
exaly +2 more sources
Antimicrobial Activity of Ceragenins against Vancomycin-Susceptible and -Resistant Enterococcus spp. [PDF]
Pharmaceuticals, 2023 Ceragenins (CSAs) are a new class of antimicrobial agents designed to mimic the activities of endogenous antimicrobial peptides. In this study, the antibacterial activities of various ceragenins (CSA-13, CSA-44, CSA-90, CSA-131, CSA-138, CSA-142, and CSA-
Mayram Hacioglu +6 more
doaj +2 more sources
Enhanced shear strength of a medical adhesive due to an antimicrobial additive
SN Applied Sciences, 2023 Adhesives play a crucial role in many industries, including medicine, construction, and electronics. In the medical field, additives may be incorporated into adhesives to enhance drug delivery or prevent infection.
Alexander J. Farnsworth +6 more
doaj +1 more source