Results 31 to 40 of about 352 (140)

Efficacy of Ceragenins in Controlling the Growth of Oral Microorganisms: Implications for Oral Hygiene Management [PDF]

Pharmaceuticals
Ensuring proper dental hygiene is of paramount importance for individuals’ general well-being, particularly for patients receiving medical care. There is a prevailing utilization of conventional oral hygiene items, including toothbrushes and mouthwashes, which have gained widespread acceptance; nevertheless, their limitations encourage investigating ...
Michał Czarnowski, Monika Słowińska, Mariusz Sawieljew, Urszula Wnorowska, Tamara Daniluk, Grzegorz Król, Maciej Karasiński, Sławomir Okła, Paul B. Savage, Ewelina Piktel, Robert Bucki   +10 more
openaire   +5 more sources

Evaluation of the in vitro activity of ceragenins against Trichomonas vaginalis

Acta Parasitologica, 2016
AbstractTrichomonosis, caused by the protozoan ...
Polat, Zubeyde Akin, Cetin, Ali, Savage, Paul B.   +2 more
openaire   +4 more sources

Ceragenin-coated endotracheal tubes for the reduction of ventilator-associated pneumonia: a prospective, longitudinal, cross-over, interrupted time, implementation study protocol (CEASE VAP study) [PDF]

BMJ Open
Background Critically ill patients are at high risk of acquiring ventilator-associated pneumonia (VAP), which occurs in approximately 20% of mechanically ventilated patients.
John Muscedere, Andrew Day, David M Maslove, Joanna S Semrau, John Gordon Boyd, Stephanie Sibley, Tracy Boyd, Patrick A Norman, Nicola E Symonds, Eric X M Meng, Hailey Hobbs   +10 more
doaj   +2 more sources

Biodegradable electrospun patch containing cell adhesion or antimicrobial compounds for trachea repair in vivo. [PDF]

Biomed Mater, 2020
Difficulty breathing due to tracheal stenosis (i.e. narrowed airway) diminishes the quality of life and can potentially be life-threatening. Tracheal stenosis can be caused by congenital anomalies, external trauma, infection, intubation-related injury ...
Townsend, Jakob M, Hukill, Makenna E, Fung, Kar-Ming, Weatherly, Robert A, Detamore, Michael S, Ohst, Devan G, Johnson, Jed K   +6 more
core   +2 more sources

Linking Ceragenins to Water-Treatment Membranes to Minimize Biofouling [PDF]

, 2012
Ceragenins were used to create biofouling resistant water-treatment membranes. Ceragenins are synthetically produced antimicrobial peptide mimics that display broad-spectrum bactericidal activity. While ceragenins have been used on bio-medical devices, use of ceragenins on water-treatment membranes is novel.
Hibbs, Michael R., Altman, Susan Jeanne, Feng, Yanshu (Brigham Young University, Provo, Utah), Savage, Paul B. (Brigham Young University, Pollard, Jacob (Brigham Young University, Branda, Steven S., Goeres, Darla (Montana State University, Bozeman, MT), Buckingham-Meyer, Kelli (Montana State University, Stafslien, Shane (North Dakota State University, Fargo, ND), Marry, Christopher, Jones, Howland D. T., Lichtenberger, Alyssa, Kirk, Matthew F., McGrath, Lucas K. (LMATA, Albuquerque, NM)   +28 more
openaire   +4 more sources

Anti-Trypanosomatid Activity of Ceragenins [PDF]

Journal of Parasitology, 2010
Cationic steroid antibiotics (CSAs), or ceragenins, are amphiphilic compounds consisting of a cholic acid backbone that is attached to several cationic amines. In this study, we tested the hypothesis that CSAs possess antiparasitic activities with minimal to no effects on mammalian cells, and thus could be used as potential therapeutic agents against ...
Diana, Lara, Yanshu, Feng, Julia, Bader, Paul B, Savage, Rosa A, Maldonado   +4 more
  +8 more sources

Core–shell magnetic nanoparticles display synergistic antibacterial effects against Pseudomonas aeruginosa and Staphylococcus aureus when combined with cathelicidin LL-37 or selected ceragenins

International Journal of Nanomedicine, 2016
Katarzyna Niemirowicz,1 Ewelina Piktel,1 Agnieszka Z Wilczewska,2 Karolina H Markiewicz,2 Bonita Durnaś,3 Marzena Wątek,4 Irena Puszkarz,3 Marta Wróblewska,5,6 Wieslawa Niklińska,7 Paul B Savage,8 Robert Bucki1,3 1Department of Microbiological ...
Niemirowicz K, Piktel E, Wilczewska AZ, Markiewicz KH, Durnaś B, Wątek M, Puszkarz I, Wróblewska M, Niklińska W, Savage PB, Bucki R   +10 more
doaj   +1 more source

Antimicrobial Finish of Polyethersulfone Membranes: Sticking Photosensitizers‐Like Marine Mussels Would Do

Advanced Engineering Materials, Volume 25, Issue 6, March 2023., 2023
A chlorin‐based photosensitizer, known from photodynamic therapy, is derivatized to realize antimicrobial finishes for water‐filtration membranes. The introduced catechol moieties known from adhesive systems of marine mussels, improve the coating and affect both positioning and packing of the photosensitizers, to retain singlet oxygen production ...
Anna Grafl, Alexander Müller, Annegret Preuß, Beate Röder, Hans. G. Börner   +4 more
wiley   +1 more source

Macromolecular Coatings for Endotracheal Tubes Probed on An Ex Vivo Extubation Setup

Advanced Materials Interfaces, Volume 10, Issue 6, February 23, 2023., 2023
Endotracheal intubation is indispensable for many surgical and medical interventions. However, patients often suffer from intubation‐induced damage to the tissue and biofouling events occurring on the surfaces of endotracheal tubes. Here, modifications to the tube surface are applied that enhance its wettability and its resistance to biofouling while ...
Bernardo Miller Naranjo, Semai Naicker, Oliver Lieleg   +2 more
wiley   +1 more source

Multidrug‐Resistant Bacteria: Their Mechanism of Action and Prophylaxis

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
In the present scenario, resistance to antibiotics is one of the crucial issues related to public health. Earlier, such resistance to antibiotics was limited to nosocomial infections, but it has now become a common phenomenon. Several factors, like extensive development, overexploitation of antibiotics, excessive application of broad‐spectrum drugs ...
Alok Bharadwaj, Amisha Rastogi, Swadha Pandey, Saurabh Gupta, Jagdip Singh Sohal, Sanket Kaushik   +5 more
wiley   +1 more source