Results 91 to 100 of about 1,649,172 (225)

Follow-up investigations of tau protein and S-100B levels in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease [PDF]

, 2005
Background: S-100B and tau protein have a high differential diagnostic potential for the diagnosis of Creutzfeldt-Jakob disease (CJD). So far there has been only limited information available about the dynamics of these parameters in the cerebrospinal ...
Cepek, L., Wiese, Birgitt, Ciesielczyk, Barbara, Cepek, Lukas, Zerr, Inga, Zerr, I., Kretzschmar, Hans A., Poser, Sigrid, Otto, Markus, Steinacker, Petra, Wiltfang, J., Schulz-Schaeffer, Walter J., Wiese, B., Bibl, Mirko, Mollenhauer, Brit, Wiltfang, Jens   +15 more
core   +1 more source

Kidney Hematopoietic Stem and Progenitor Cells Contribute to Myeloid Development and Pathology in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi, Seyoung Jung, Jeong Ho Joo, Young‐Eun Kim, Heounjeong Go, Yong‐Gil Kim, Chang‐Keun Lee, Bin Yoo, Jeong Seok Lee, Seokchan Hong   +9 more
wiley   +1 more source

Analysis of cerebrospinal fluid metabolites in patients with primary or metastatic central nervous system tumors

Acta Neuropathologica Communications, 2018
Cancer cells have altered cellular metabolism. Mutations in genes associated with key metabolic pathways (e.g., isocitrate dehydrogenase 1 and 2, IDH1/IDH2) are important drivers of cancer, including central nervous system (CNS) tumors.
Leomar Y. Ballester, Guangrong Lu, Soheil Zorofchian, Venkatrao Vantaku, Vasanta Putluri, Yuanqing Yan, Octavio Arevalo, Ping Zhu, Roy F. Riascos, Arun Sreekumar, Yoshua Esquenazi, Nagireddy Putluri, Jay-Jiguang Zhu   +12 more
doaj   +1 more source

Medulloblastoma cerebrospinal fluid reveals metabolites and lipids indicative of hypoxia and cancer-specific RNAs

Acta Neuropathologica Communications, 2022
Medulloblastoma (MB) is the most common malignant brain tumor in children. There remains an unmet need for diagnostics to sensitively detect the disease, particularly recurrences.
Bongyong Lee, Iqbal Mohamad, Rudramani Pokhrel, Rabi Murad, Menglang Yuan, Stacie Stapleton, Chetan Bettegowda, George Jallo, Charles G. Eberhart, Timothy Garrett, Ranjan J. Perera   +10 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Harmonizing definitions in liquid biopsy: A terminology framework by the international society of liquid biopsy

The rapid expansion of liquid biopsy (LB) throughout the cancer care continuum is evidenced by the striking increase in annual publications, rising from approximately 100 per year in the early 2000s to more than 2200 in recent years.
Mayo de las Casas, Clara, Leighl, Natasha B., Gandara, David, Rolfo, Christian, Malapelle, Umberto, Urum, Yuksel, Khorshid, Ola, Serrano, Maria José, Jantus-Lewintre, Eloísa, Raez, Luis, Aggarwal, Charu, Calabuig-Fariñas, Silvia, Reduzzi, Carolina, Fusco, Nicola   +13 more
core   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

lottaer/liquid-biopsy-denoising: v.1.0.0

Code for the thesis "Deconvolution methods for quantifying copy number variations in liquid biopsy ...
Lotta Eriksson, linneahallin
core   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Electrochemical liquid biopsy across cancer care pathway

Liquid biopsy has emerged as a powerful approach for tracking tumor dynamics through circulating biomarkers such as cell-free tumor DNA (ctDNA), circulating tumor cells (CTCs), extracellular vesicles (EVs), microRNAs (miRNAs) and soluble proteins. Unlike
De Laurentiis, Michelino, Cinti, Stefano, Caraglia, Michele, Raucci, Ada, Giordano, Antonio, Singh, Sima, Misso, Gabriella, Miglione, Antonella, Cocco, Stefania, Kalligosfyri, Panagiota M.   +9 more
core   +1 more source