Results 151 to 160 of about 39,021 (326)

Tables S1 - S10 from Evolution of Castration-Resistant Prostate Cancer in ctDNA during Sequential Androgen Receptor Pathway Inhibition

, 2023
Matti Annala, Sinja Taavitsainen, Daniel Khalaf, Gillian Vandekerkhove, Kevin Beja, Joonatan Sipola, Evan W. Warner, Cameron Herberts, Amanda Wong, Simon Fu, Daygen L. Finch, Conrad D. Oja, Joanna Vergidis, Muhammad Zulfiqar, Bernhard J. Eigl, Christian K. Kollmansberger, Matti Nykter, Martin Gleave, Kim N., Alexander W. Wyatt   +19 more
openalex   +1 more source

Urinary Tumor DNA to Identify Candidates for Repeat Transurethral Resection in Non‐Muscle‐Invasive Bladder Cancer

Cancer Science, EarlyView.
Urinary tumor DNA (utDNA) represents a powerful noninvasive biomarker to refine the need for repeat TURBT in high‐risk NMIBC. In our cohort of 161 patients, utDNA testing achieved superior accuracy to cytology, strongly predicted residual disease and recurrence, and could safely reduce unnecessary repeat resections by up to one‐third.
Zihan Xue, Yunkai Qie, Chong Shen, Zhouliang Wu, Houyuan Chen, Yuda Lin, Rongjiang Li, Shiwang Huang, Hailong Hu   +8 more
wiley   +1 more source

Data from Early Reduction in ctDNA Predicts Survival in Patients with Lung and Bladder Cancer Treated with Durvalumab

, 2023
Rajiv Raja, Michael Kuziora, Philip Z. Brohawn, Brandon W. Higgs, Ashok Gupta, Phillip A. Dennis, Koustubh Ranade   +6 more
openalex   +1 more source

Therapeutic Strategies to Overcome Payload Resistance of Trastuzumab Deruxtecan in HER2‐Positive Cancers

Cancer Science, EarlyView.
Overexpression of ABC transporters, especially ABCG2 and ABCB1, mediates acquired resistance to T‐DXd in HER2‐positive cancers. Inhibition of these transporters restored T‐DXd efficacy, highlighting efflux‐mediated resistance as a potential therapeutic target. ABSTRACT Antibody–drug conjugates (ADCs) are emerging as a promising class of targeted cancer
Yuya Murase, Shigeki Nanjo, Sachiko Arai, Sota Kondo, Hayato Koba, Yifeng Liu, Koji Fukuda, Shigeki Sato, Jun Kinoshita, Noriyuki Inaki, Tsukasa Ueda, Shunichi Nomura, Yuichi Tambo, Takahiro Shimizu, Masafumi Horie, Daichi Maeda, Richard W. Wong, Kazuyoshi Hosomichi, Takafumi Kobayashi, Satoshi Watanabe, Kenta Yamamura, Noriyuki Ohkura, Miki Abo, Seiji Yano   +23 more
wiley   +1 more source

Supplementary file containing supplementary Table 1, 2, 3 and Supplementary Figure 1a,1b,1c and 1d. from Correlation of Somatic Genomic Alterations Between Tissue Genomics and ctDNA Employing Next-Generation Sequencing: Analysis of Lung and Gastrointestinal Cancers

, 2023
Omer M. Toor, Zaheer Ahmed, Waled Bahaj, Urooge Boda, Lee S. Cummings, Megan E. McNally, Kevin Kennedy, Timothy Pluard, Arif Hussain, Janakiraman Subramanian, Ashiq Masood   +10 more
openalex   +1 more source

Genomic Profiling of NGS-based ctDNA from Chinese Non-Small Cell Lung Cancer Patients [PDF]

, 2023
Yanfeng Xi, Zhongyuan Bai, Sihang Gao, Jianghong Guo, Zhen Zhang, Hongling Zhang, Li Qu, Bing Xu, Weiwei Wang, Guangyu Shan, Wei Cui, Wenqi Bai, Xiaoyong Ji   +12 more
openalex   +1 more source

Systemic Surveillance Guidelines for Uveal Melanoma: A Systematic Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Uveal melanoma (UM) is the most common primary intraocular tumour. Despite effective local therapies, UM has a high risk of metastatic recurrence, most frequently to the liver. A significant proportion of patients treated definitively for primary UM eventually experience metastatic disease. Systemic surveillance to detect recurrence
Farzana Y. Zaman, Aisha Ghaus, Mark Shackleton, Damien Kee, Anthony M. Joshua, Roderick O'Day, Malaka Ameratunga   +6 more
wiley   +1 more source

Plasma EGFR mutation ctDNA dynamics in patients with advanced EGFR-mutated NSCLC treated with Icotinib: phase 2 multicenter trial result

Scientific Reports
Plasma epidermal growth factor receptor mutation (EGFRm) circulating tumor DNA (ctDNA) dynamics exhibit promise in predicting outcomes in patients with EGFRm-advanced non-small cell lung cancer (NSCLC).
Yaping Hong, Wu Zhuang, Jinhuo Lai, Haipeng Xu, Yueming He, Jinlan Lin, Qin Shi, Shengjia Chen, Zhangzhou Huang, Shijie Chen, Dongzhu Lu, Gen Lin, Yunjian Huang   +12 more
doaj   +1 more source

El papel de la enfermería en la Biopsia Líquida [PDF]

, 2019
Introducción: El cáncer sigue constituyendo una de las principales causas de morbilidad del mundo. Las estimaciones poblacionales indican que el número de casos probablemente aumente a un 70% en las próximas décadas. Desde el año 2000 en nuestro país, el
Villaverde Hueso, María
core  

Beyond PD‐1: Mechanisms of Resistance to Checkpoint Blockade in Classical Hodgkin Lymphoma and Next‐Generation Immune Strategies

European Journal of Haematology, EarlyView.
ABSTRACT PD‐1 inhibitors have reshaped the treatment landscape of classical Hodgkin lymphoma, yet a substantial proportion of patients exhibit primary or acquired resistance driven by tumor‐intrinsic alterations, immunosuppressive microenvironmental signals, metabolic constraints, and EBV‐mediated modulation.
Santino Caserta, Enrica Antonia Martino, Mamdouh Skafi, Maria Eugenia Alvaro, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Ernesto Vigna, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source