Results 171 to 180 of about 47,434 (363)

Postoperative ctDNA monitoring: a canary in a coalmine

Annals of Oncology, 2021
M.A. Lumish, Yelena Y. Janjigian, N. Tarazona   +2 more
openaire   +4 more sources

Nanosensors in Leukemia Management: Pioneering Real‐Time Biomarker Detection for Precision Oncology

Nano Select, EarlyView.
This review highlights pioneering nanosensors designed for real‐time leukemia biomarker detection, integrating advanced nanomaterials such as liposomes, polymeric nanoparticles and quantum dots. It examines electrochemical, optical and magnetic detection mechanisms, the applications across AML, ALL, CML, and CLL subtypes, and clinical translation ...
Hamed Soleimani Samarkhazan, Mohammad Navid Khaksari, Amirhossein Mirzazadeh, Mohammad Siavashi, Niloofar Pilehvari, Mohammad Hossein Mohammadi   +5 more
wiley   +1 more source

Concept and feasibility of the Augsburg Longitudinal Plasma Study (ALPS) – a prospective trial for comprehensive liquid biopsy-based longitudinal monitoring of solid cancer patients

Journal of Laboratory Medicine
Liquid biopsy (LBx) provides diagnostic, prognostic and predictive insights for malignant diseases and offers promising applications regarding tumor burden, tumor heterogeneity and clonal evolution.
Sommer Sebastian, Schmutz Maximilian, Hildebrand Kathrin, Schiwitza Annett, Benedikt Selinah, Eberle Maria, Mögele Tatiana, Sultan Aziz, Reichl Lena, Campillo Maria, Uhrmacher Luise, Nikolic Ana Antic, Bundschuh Ralph, Lapa Constantin, Kuhlen Michaela, Dintner Sebastian, Langer Angela, Märkl Bruno, Wendler Thomas, Tehlan Kartikay, Kröncke Thomas, Wahle Maria, Mann Matthias, Casadei Nicolas, Pogoda Michaela, Hummler Simone, Sax Irmengard, Schlesner Matthias, Kubuschok Boris, Trepel Martin, Claus Rainer   +30 more
doaj   +1 more source

561P Targeted sequencing of plasma ctDNAs and primary tumors identified heterogeneity and homogeneity in advanced gastric cancer [PDF]

, 2016
Jinbo Gao
openalex   +1 more source

Toward Precision Chemotherapy for Pancreatic Cancer Guided by Transcriptomic Signatures

United European Gastroenterology Journal, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers, with chemotherapy as the mainstay but highly variable efficacy and toxicity. Current regimens, such as FOLFIRINOX and gemcitabine‐based combinations, are selected empirically without validated biomarkers to guide choice.
Brice Chanez, Matthieu Delaye, Nicolas Fraunhoffer, Juan Iovanna, Cindy Neuzillet, Nelson Dusetti   +5 more
wiley   +1 more source

Clinical utility of circulating tumor DNA (ctDNA) in resectable pancreatic ductal adenocarcinoma (PDAC) [PDF]

, 2016
Hui‐Li Wong, Kevin Bushell, Joanna M. Karasinska, Sarah E. Arthur, Prasath Pararajalingam, Ryan D. Morin, David F. Schaeffer, Daniel J. Renouf   +7 more
openalex   +1 more source

Exome‐wide molecular insights from blood and urine liquid biopsies in genitourinary cancers

UroPrecision, EarlyView.
Abstract Background Liquid biopsy has emerged as a non‐invasive method for real‐time cancer monitoring especially in genitourinary (GU) oncology. Most current studies utilize a panel‐based molecular profiling ranging from 50–600 genes; however, a comprehensive exome‐wide profiling of real‐world patient samples has been lacking. Methods Over 2000 liquid
Eric Jia, Tiantian Zheng, Yong Huang, Pan Du   +3 more
wiley   +1 more source

RARE-30. PEDIATRIC GLIOBLASTOMA IN THE POST-TEMOZOLOMIDE ERA: OUTCOMES AND CHARACTERISTICS [PDF]

, 2019
INTRODUCTION Glioblastoma (GBM) is the most common brain tumor, however, is a rare occurrence in children and is poorly characterized. We evaluated the characteristics and outcomes of pediatric GBM (pGBM).
Aghi, Manish, Berger, Mitchel, Chandra, Ankush, Gupta, Nalin, McDermott, Mike, Oh, Taemin, Shah, Sumedh, Wadhwa, Harsh   +7 more
core  

447PD Modified ctDNA extraction method combined with blocker PCR assays improves the liquid biopsy efficiency in NSCLC patients [PDF]

, 2016
M. Zhang, Zhuozhi Gong, C. Li, Hengbo Ji, J. Hu, Qiuhong Hong, Y. Hou, Fawei Huang, Weiyu Guo, Dejing Zhang, X. Zhang   +10 more
openalex   +1 more source

The regulatory effects and applications of TIGIT/CD155 on the tumor microenvironment in HCC

VIEW, EarlyView.
Background The interaction between TIGIT and CD155 compromises immune cell efficacy in tumor targeting, potentially driving hepatocellular carcinoma (HCC) progression through diverse molecular pathways. What Was Done This study investigates the interplay between CD155 and TIGIT in regulating CD8+ T cell function and elucidates its implications in HCC ...
Wenting Li, Yukun Li, Yao Li, Mingqi Yang, Haichuan Peng, Hongwei Sun, Ping Jiang, Yizhun Zhu, Qiang Chen, Xiaobing Duan, Wei Zhao   +10 more
wiley   +1 more source