Results 211 to 220 of about 69,132 (251)

Immune checkpoint-engineered virus-like particles induce antigen-specific immune tolerance and protect against food allergy. [PDF]

NPJ Vaccines
Vinot PA, Vigneron J, Marsande J, Levacher B, Tchitchek N, Klatzmann D, Bellier B.   +6 more
europepmc   +1 more source

Induction of Humoral and Cellular Immunity After SARS-CoV-2 JN.1 Vaccination in Individuals With and Without Prior Infection. [PDF]

Eur J Immunol
Diener C, Urschel R, Bronder S, Guckelmus C, Eckel J, Hielscher F, Bojkova D, Ciesek S, Widera M, Schmidt T, Sester M.   +10 more
europepmc   +1 more source

Immune checkpoints in lung cancer. [PDF]

Breathe (Sheff)
Garrido-Martín EM, Kontic M, Rooney C, Mansouri N.   +3 more
europepmc   +1 more source

Drug resistance mechanisms of immunotherapy and translational strategies for reversing resistance for hepatocellular carcinoma: from bench to bedside. [PDF]

Front Immunol
Zhang C, Zhang D, Wen X, Liu S.
europepmc   +1 more source

The central role of radiotherapy in remodeling the tumor immune microenvironment: mechanisms and therapeutic implications. [PDF]

Front Cell Dev Biol
Yi Z, Chen N, Jiang X, Hu X.
europepmc   +1 more source

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Cytotoxic T‐lymphocyte antigen‐4 (CTLA‐4) gene polymorphism and susceptibility to non‐Hodgkin's lymphoma

American Journal of Hematology, 2004
AbstractThe CTLA‐4 molecule plays an important role in immune regulation by downregulating activation of T cells. Polymorphisms in the CTLA‐4 gene have been shown to be associated to a number of autoimmune diseases including blood disorders. In this study, the intragenic polymorphisms of the CTLA‐4 gene at position −318*C/T, +49*A/G, and the ...
Giovanna Piras
exaly   +3 more sources

The role of CD28 and cytotoxic T‐lymphocyte antigen‐4 (CTLA-4) in regulatory T‐cell biology

Immunological Reviews, 2006
Summary:  The profound influence of CD28 and cytotoxic T‐lymphocyte antigen‐4 (CTLA‐4) on T‐cell immunity has been known for over a decade, yet the precise roles played by these molecules still continue to emerge. Initially viewed as molecules that provide cell‐intrinsic costimulatory and inhibitory signals, recent evidence suggests that both CD28 and ...
Lucy Walker, David Sansom
exaly   +3 more sources

B70 antigen is a second ligand for CTLA-4 and CD28

Nature, 1993
The membrane antigen B7/BB1 (refs 1, 2) is expressed on activated B cells, macrophages and dendritic cells, and binds to a counter-receptor, CD28, expressed on T lymphocytes and thymocytes. Interaction between CD28 and B7 results in potent costimulation of T-cell activation initiated through the CD3/T-cell receptor complex.
M, Azuma, D, Ito, H, Yagita, K, Okumura, J H, Phillips, L L, Lanier, C, Somoza   +6 more
openaire   +2 more sources