Results 31 to 40 of about 2,755 (211)

CTN

TRAVESSIA - revista do migrante, 1999
Para início de conversa, o relato a seguir são impressões acerca do Centro de Tradições NordestinasCTN, resultantes de uma série de visitas realizadas durante o mês de março de 1999. Três pesquisadoras (Dulce, Soraia e Mira) envolvidas em suas respectivas teses que abordam a migração, tendo em comum também a origem nordestina, partiram para uma espécie
Mirandulina Maria Moreira Azevedo, Dulce Maria Tourinho Baptista, Maria do Socorro Carlos Vidal   +2 more
openaire   +2 more sources

Structural basis for proton coupled cystine transport by cystinosin

Nature Communications, 2022
Mutations in CTNS, the lysosomal cystine-proton symporter, cause cystinosis. Here authors report crystal structures of CTNS from Arabidopsis thaliana in complex with cystine, and establish the mode of ligand recognition and mechanism for proton-coupled ...
Mark Löbel, Sacha P. Salphati, Kamel El Omari, Armin Wagner, Stephen J. Tucker, Joanne L. Parker, Simon Newstead   +6 more
doaj   +1 more source

Horizontal collaboration in the freight transport sector: barrier and decision-making frameworks

European Transport Research Review, 2021
In the freight transport sector, competing companies horizontally collaborate through establishing Collaborative Transport Networks (CTNs). Fruitful implementation of CTNs will leverage environmental and socio-economic goals of sustainable development in
Ahmed Karam, Kristian Hegner Reinau, Christian Richter Østergaard   +2 more
doaj   +1 more source

Vitamin D repletion ameliorates adipose tissue browning and muscle wasting in infantile nephropathic cystinosis‐associated cachexia

Journal of Cachexia, Sarcopenia and Muscle, 2020
Background Ctns−/− mice, a mouse model of infantile nephropathic cystinosis, exhibit hypermetabolism with adipose tissue browning and profound muscle wasting. Ctns−/− mice are 25(OH)D3 and 1,25(OH)2D3 insufficient.
Wai W. Cheung, Sheng Hao, Zhen Wang, Wei Ding, Ronghao Zheng, Alex Gonzalez, Jian‐Ying Zhan, Ping Zhou, Shiping Li, Mary C. Esparza, Hal M. Hoffman, Richard L. Lieber, Robert H. Mak   +12 more
doaj   +1 more source

Genetic Landscape of Nephropathic Cystinosis in Russian Children

Frontiers in Genetics, 2022
Nephropathic cystinosis is a rare autosomal recessive disorder characterized by amino acid cystine accumulation and caused by biallelic mutations in the CTNS gene.
K. V. Savostyanov, A. A. Pushkov, O. A. Shchagina, V. V. Maltseva, E. A. Suleymanov, I. S. Zhanin, N. N. Mazanova, A. P. Fisenko, P. S. Mishakova, A. V. Polyakov, E. V. Balanovska, R. A. Zinchenko, A. N. Tsygin   +12 more
doaj   +1 more source

Cystinosis and two rare mutations in CTNS gene: two case reports

Journal of Medical Case Reports, 2022
Background Cystinosis is an autosomal recessive disorder characterized by an accumulation of the amino acid cystine in lysosomes throughout the body. Cystinosis is an inherited disease resulting from the failure of lysosomal cystine transport.
Sepideh Gholami Yarahmadi, Fatemeh Sarlaki, Saeid Morovvati   +2 more
doaj   +1 more source

CTNS Molecular Genetics Profile in a Portuguese Cystinosis Population [PDF]

, 2018
Background: Cystinosis is a multisystemic autosomal recessive deficiency of the lysosomal membrane transporter protein (cystinosin) caused by mutations in CTNS gene.
Costa, Teresa, Vilarinho, Laura, Sousa, David, Carmona, Célia, Ramos, Sónia, Neiva, Raquel, Ferreira, Filipa, Mota, Conceição, Carmo Macário, Maria do, Pinto, Helena, Magriço, Rita, Oliveira, João Paulo, Tavares, Isabel, Marcão, Ana, Leal, Inês, Lopes, Daniela, Gomes, Ana Marta   +16 more
core   +1 more source

amMSC microvesicle transfer of CTNS^Red to acidic intracellular compartment of CTNS(−/−) mutant fibroblasts.

, 2013
(a) amMSC stably transfected with CTNSRed immunofluorescent protein. (b) CTNSRed in amMSC microvesicles. (c) single confocal plane showing CTNSRed protein in amMSC (circles) and in co-cultured GFP-tagged CTNS(−/−) mutant fibroblasts (arrows). Dashed line
Reyhan El-Kares (311952), Nicoletta Eliopoulos (311965), Jing Zhao (21160), Diana M. Iglesias (311951), Lambertus van den Heuvel (311962), Francesco Bellomo (311954), Jaan Toelen (311961), Yoon Kow Young (311964), LeeLee Chu (311963), Paul Goodyer (311966), Francesco Emma (311956), Anna Taranta (311953), Elena Levtchenko (311960), Martine Besouw (311958)   +13 more
core   +1 more source

Pang Yuk Cheung: Effects of oral cysteamine treatment on Ctns knockout rats

, 2022
Cystinosis is a rare genetic disorder caused by mutations in the gene CTNS which mainly affects the kidneys. Without treatment, this results in renal failure early in life.
Pang Yuk Cheung (1210017)
core   +1 more source

The CTNS-MTORC1 axis couples lysosomal cystine to epithelial cell fate decisions and is a targetable pathway in cystinosis [PDF]

, 2023
Differentiation and fate decisions are critical for the epithelial cells lining the proximal tubule (PT) of the kidney, but the signals involved remain unknown.
Devuyst, Olivier; https://orcid.org/, Luciani, Alessandro; https://orcid.org/   +1 more
core   +2 more sources