Results 41 to 50 of about 3,070 (212)
Effect of co-culture with CTNS-expressing cells on cystine content of mutant CTNS cells.
, 2013 (a) Cystine content of CTNS(−/−) fibroblasts co-cultured with increasing amounts of wildtype amMSC. (b) Cystine content of GFP-tagged CTNS(−/−) ciPTEC isolated by FACS after co-culture with unlabelled wildtype amMSC, mutant ciPTEC or CTNS-corrected ...
Reyhan El-Kares (311952) +13 more
core +1 more source
Histological features of kidneys from CtnsY226X/Y226X vs. Ctns+/+mice.
, 2019 A. Cystine crystals in 6-months old Ctns+/+ and CtnsY226X/Y226X female kidney. B. Bowman’s capsule/proximal tubule lesions in 6-month old CtnsY226X/Y226X male kidney vs Ctns+/+ wildtype.
Pedro Huertas (4891903) +9 more
core +1 more source
Carbon Energy, EarlyView.Cyanated carbon dots (CN‐CDs) are synthesized by the hydrothermal method with carboxymethyl cellulose and cyanobenzoic acid, and CD‐CTN is obtained in situ via cyclotrimerization of CN‐CDs. CD‐CTN possesses excellent photothermal catalytic H2O2 production in seawater, and desalted H2O2 could be obtained, which demonstrates the practical application for
Xiaoxia Chen +13 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1237-1245, April 2025.Abstract Aims Immune checkpoint inhibitors (ICI) are the cornerstone of modern oncology; however, side effects such as ICI‐related myocarditis (irM) can be fatal. Recently, Bonaca proposed criteria for irM; however, it is unknown if they correlate well with cardiovascular (CV) ICI‐related adverse events.
Lorenzo Braghieri +12 more
wiley +1 more source
Pang Yuk Cheung: Effects of oral cysteamine treatment on Ctns knockout rats
, 2022 Cystinosis is a rare genetic disorder caused by mutations in the gene CTNS which mainly affects the kidneys. Without treatment, this results in renal failure early in life.
Pang Yuk Cheung (1210017)
core +1 more source
FlexMat, EarlyView.This review organizes flexible wearable electronics for cardiovascular monitoring into four interconnected information layers: surface electrophysiology, hemodynamic sensing, vascular imaging, and biofluid biomarker analysis. This framework clarifies how electrical rhythm, vascular loading, structural and flow‐related features, and biochemical states ...
Qiao Chen +5 more
wiley +1 more source
Leptin signalling altered in infantile nephropathic cystinosis‐related bone disorder
Journal of Cachexia, Sarcopenia and MuscleBackground The CTNS gene mutation causes infantile nephropathic cystinosis (INC). Patients with INC develop Fanconi syndrome and chronic kidney disease (CKD) with significant bone deformations.
Wai W. Cheung +5 more
doaj +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
EMBO Molecular Medicine, 2015 Metabolite accumulation in lysosomal storage disorders (LSDs) results in impaired cell function and multi‐systemic disease. Although substrate reduction and lysosomal overload‐decreasing therapies can ameliorate disease progression, the significance of ...
Gennaro Napolitano +7 more
doaj +1 more source
Urine-Derived Kidney Progenitor Cells in Cystinosis
Cells, 2022 Nephropathic cystinosis is an inherited lysosomal storage disorder caused by pathogenic variants in the cystinosin (CTNS) gene and is characterized by the excessive shedding of proximal tubular epithelial cells (PTECs) and podocytes into urine ...
Koenraad Veys +15 more
doaj +1 more source