Results 171 to 180 of about 9,957 (210)

4-Azidotetrahydroquinazoline derivatives in CuAAC reaction

Mendeleev Communications, 2020
4-Azido-2-methyltetrahydroquinazoline N-oxide cleanly undergoes the copper( i )-catalyzed azide–alkyne cycloaddition (CuAAC) reaction with alkynes to give new conjugates with pyrimidine N-oxide and triazole moieties. Its deoxygenated analogue, 4-azido-2-methyltetrahydroquinazoline, is inert in CuACC process due to the shift of imidoyl azide–tetrazole ...
Anna A. Nazarova, Kseniya N. Sedenkova, Dmitry A. Vasilenko, Yuri K. Grishin, Tamara S. Kuznetsova, Elena B. Averina   +5 more
openaire   +1 more source

Highly Enantioselective CuAAC of Functional Tertiary Alcohols Featuring an Ethynyl Group and Their Kinetic Resolution.

Angewandte Chemie, 2020
The first highly enantioselective Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) of tertiary alcohols and their kinetic resolution is reported.
Kui Liao, Yi Gong, Ren‐Yi Zhu, Cai-Ming Wang, F. Zhou, Jian Zhou   +5 more
semanticscholar   +1 more source

A Multicomponent Reaction Integrating Selenium(II)-Nitrogen Exchange (SeNEx) Chemistry and Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC).

Angewandte Chemie
Multicomponent reactions (MCRs) are powerful tools for rapidly constructing compound libraries with sufficient molecular diversity and complexity. Herein, to fully leverage a third aspect of molecular diversity enabled by the selenium-nitrogen exchange ...
Wei Hou, Wei Zhou, Xiaohui Zhou, Zhikun Yang, Huhui Xia, Yan Wang, Keren Xu, Shaoneng Hou, Shuning Zhang, Dong-Mei Cui, Peixiang Ma, Hongtao Xu   +11 more
semanticscholar   +1 more source

Construction of sequence-defined polytriazoles by IrAAC and CuAAC reactions.

Chemical Communications, 2020
Here we report the first synthesis of sequence-defined polytriazoles, in which different side groups are sequentially anchored to the C-5 position of 1,2,3-triazole rings.
Changhong Ju, Congcong Meng, Jiahao Ma, Xueyan Zhang, S. Ding   +4 more
semanticscholar   +1 more source

Copper-catalysed azide–alkyne cycloadditions (CuAAC): an update

Organic & Biomolecular Chemistry, 2015
The recent advances in the copper-catalysed azide–alkyne cycloaddition (CuAAC) reactions are reviewed.
Estela, Haldón, M Carmen, Nicasio, Pedro J, Pérez   +2 more
openaire   +2 more sources

Bile acid bearing poly (vinyl chloride) nanofibers by combination of CuAAC click chemistry and electrospinning process

, 2020
This study aims to deposit most common bile acids such as lithocholic acid (LCA) and chenodeoxycholic acid (CDCA) bearing poly (vinyl chloride) nanofiber (PVC-LCA and PVC-CDCA) coatings on glass slides surface using a combination method by employing ...
C. Altinkok, H. Karabulut, M. Taşdelen, G. Acik   +3 more
semanticscholar   +1 more source

2.2 CuAAC in Peptidomimetics and Protein Mimics

2022
AbstractThe tremendous recent developments in click chemistry, including the impressive developments of strain-promoted cycloaddition reagents, all started with the copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction conceived by Meldal et al. and Sharpless et al.
T. J. Meuleman, R. M. J. Liskamp
openaire   +1 more source

Facile Synthesis of Sequence-Regulated Synthetic Polymers Using Orthogonal SuFEx and CuAAC Click Reactions.

Angewandte Chemie, 2018
The orthogonal sulfur-fluoride exchange reaction (SuFEx) and copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) are employed to synthesize sequence-regulated synthetic polymers.
Cangjie Yang, J. P. Flynn, Jia Niu
semanticscholar   +1 more source

A Fluxional Copper Acetylide Cluster in CuAAC Catalysis

Angewandte Chemie International Edition, 2015
AbstractA molecularly defined copper acetylide cluster with ancillary N‐heterocyclic carbene (NHC) ligands was prepared under acidic reaction conditions. This cluster is the first molecular copper acetylide complex that features high activity in copper‐catalyzed azide–alkyne cycloadditions (CuAAC) with added acetic acid even at −5 °C.
Ata, Makarem, Regina, Berg, Frank, Rominger, Bernd F, Straub   +3 more
openaire   +2 more sources

When CuAAC 'Click Chemistry' goes heterogeneous

Catalysis Science & Technology, 2016
Within the green chemistry context, heterogeneous catalysis is more and more applied to organic synthesis. The well known ‘click chemistry’ and especially its flagship, the copper-catalyzed azide–alkyne cycloaddition reaction (CuAAC), is now catch up by such heterogenisation process and copper ions or metals have been grafted or deposited on or into ...
S. Chassaing, V. Bénéteau, P. Pale
openaire   +1 more source