Results 181 to 190 of about 9,957 (210)
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Polymer “Clicking” by CuAAC Reactions
Macromolecular Rapid Communications, 2008AbstractThe CuAAC “click” reaction has developed as one of the most useful and widely employed reactions in ligation within polymer chemistry. This is due to the unique properties of the Cu(I) catalysis which renders the reaction quantitative even at low concentrations, orthogonal with other chemistries and extremely robust.
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Applications of Surface Science, 2019
Superabsorbent polymer (SAP) hydrogel was synthesized and surface-modified by a “click” reaction approach to enhance the mechanical and antibacterial properties of the gel.
N. Moini +3 more
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Superabsorbent polymer (SAP) hydrogel was synthesized and surface-modified by a “click” reaction approach to enhance the mechanical and antibacterial properties of the gel.
N. Moini +3 more
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Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC)
2022Contains fulltext : 310029.pdf (Publisher’s version ) (Closed access)
Rutjes, F.P.J.T., Ort, F.F.
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Bioconjugate chemistry, 2019
Site-specific modification of peptides and proteins is an important method for introducing an artificial function to the protein surface. Recently, we found that new bioconjugation reagents, 6-(azidomethyl)-2-pyridinecarbaldehyde (6AMPC) derivatives ...
Nozomu Inoue, A. Onoda, Takashi Hayashi
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Site-specific modification of peptides and proteins is an important method for introducing an artificial function to the protein surface. Recently, we found that new bioconjugation reagents, 6-(azidomethyl)-2-pyridinecarbaldehyde (6AMPC) derivatives ...
Nozomu Inoue, A. Onoda, Takashi Hayashi
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‘Click’ glycosylation of peptides through cysteine propargylation and CuAAC
Bioorganic & Medicinal Chemistry, 2014'Click' glycosylation of cysteine-containing peptides were carried out in good yield by Copper(I)-catalyzed Azide-Alkyne Cycloaddition (CuAAC). For that peptides were functionalized though direct propargylation of the cysteine residue allowing their use in CuAAC with suitable free or protected azido sugars of gluco, manno and galacto configuration ...
Sandrine Lamandé-Langle +8 more
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Click processes orthogonal to CuAAC and SuFEx forge selectively modifiable fluorescent linkers
Nature Chemistry, 2023Paulo H S Paioti +8 more
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Fluktuierender Kupferacetylid‐Cluster in der CuAAC‐Katalyse
Angewandte Chemie, 2015AbstractEin molekular definierter Kupferacetylidcluster mit N‐heterocyclischen Carben‐Steuerliganden (NHC) wurde zum ersten Mal unter sauren Reaktionsbedingungen hergestellt. Dieser Cluster ist der erste molekulare Kupferacetylid‐Komplex, der eine hohe Aktivität in der Kupfer‐katalysierten Azid‐Alkin‐Cycloaddition aufweist, bei Essigsäurezusatz sogar ...
Ata Makarem +3 more
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Star‐Shaped Polyacrylates: Highly Functionalized Architectures via CuAAC Click Conjugation
Macromolecular Rapid Communications, 2009AbstractWell‐defined functional star‐shaped polymer structures with up to 29 arms have been successfully synthesized by the combination of atom transfer radical polymerization (ATRP) and click chemistry. First, azide end‐functionalized poly(isobornyl acrylate) (PiBA) star‐shaped polymers were prepared by successive ATRP and bromine substitution ...
Lammens, M. +4 more
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Efficient CuAAC click formation of functional hemoglobin bis-tetramers
Chemical Communications, 2010A cross-linked hemoglobin bis-tetramer with oxygenation properties appropriate for a red cell substitute is produced by CuAAC conjugation of a dialkyne and two equivalents of an azide of β,β-cross-linked hemoglobin. The latter is formed efficiently by the aminolysis of the 3,5-dibromosalicylate ester of the β-82-β'-82-bis trimesyl amide of human ...
Ying, Yang, Ronald, Kluger
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Copper catalysed azide–alkyne cycloaddition (CuAAC) in liquid ammonia
Organic & Biomolecular Chemistry, 2012Copper(I) catalysed azide-alkyne cycloaddition reactions (CuAAC) occur smoothly in liquid ammonia (LNH(3)) at room temperature to give exclusively 1,4-substituted 1,2,3-triazoles with excellent yields (up to 99%). The CuAAC reactions in liquid ammonia require relatively small amounts of copper(I) catalyst (0.5 mole%) compared with that in conventional ...
Pengju, Ji +2 more
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