ChemInform Abstract: Phase Transfer Agent Assisted Biphasic CuAAC Reaction.
ChemInform, 2015AbstractThe method is applied to the synthesis of an immunostimulating α‐galaytosylceramide analogue.
Jae Hyun Kim, Sanghee Kim
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Modulating catalytic activity of polymer‐based cuAAC “click” reactions
Journal of Polymer Science Part A: Polymer Chemistry, 2011AbstractThe copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) reaction is used to synthesize complex polymer architectures. In this work, we demonstrate the control of this reaction at 25 °C between polystyrene (PSTY) chains through modulating the catalytic activity by varying the combinations of copper source (i.e., Cu(I)Br or copper wire ...
Bell, Craig A. +3 more
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Extent of the Oxidative Side Reactions to Peptides and Proteins During the CuAAC Reaction
Bioconjugate Chemistry, 2016The copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction is a powerful tool for bioconjugation of biomolecules, particularly proteins and peptides. The major drawback limiting the use of the CuAAC reaction in biological systems is the copper-mediated formation of reactive oxygen species (ROS), leading to the oxidative degradation of proteins or
Siheng, Li +8 more
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CuAAC click reactions for the design of multifunctional luminescent ruthenium complexes
Dalton Transactions, 2016CuAAC (Cu(i) catalyzed azide–alkyne cycloaddition) click chemistry has emerged as a versatile tool in the development of photoactive ruthenium complexes with multilateral potential applicability. Three general concepts for their synthesis and selected applications are discussed.
Natalia, Zabarska +2 more
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Copper supported silica-based nanocatalysts for CuAAC and cross-coupling reactions
Reaction Chemistry & Engineering, 2022Recent advances in Cu/SiO2-based heterogeneous catalysts for click reaction, C–N, C–S, and C–O coupling reactions are reviewed and summarized.
Pitchaimani Veerakumar +4 more
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ChemInform Abstract: CuAAC: The Quintessential Click Reaction
ChemInform, 2013AbstractReview: 108 refs.
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Exposure to air boosts CuAAC reactions catalyzed by PEG-stabilized Cu nanoparticles
Chemical Communications, 2017The catalytic activity of Cu(0) NPs is boosted upon aerobic oxidation, forming Cu2O NPs, and further improved on an SBA-15 support.
Fangyu Fu +9 more
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Simultaneous Photoinduced ATRP and CuAAC Reactions for the Synthesis of Block Copolymers
Macromolecular Rapid Communications, 2014Atom transfer radical polymerization (ATRP) and copper‐catalyzed azide–alkyne cycloaddition (CuAAC) reactions, both utilizing copper(I) (Cu(I)) complexes, make a tremendous progress in synthetic polymer chemistry. Independently or in combination with other polymerization processes, they give access to the synthesis of polymers with well‐defined ...
Eljesa, Murtezi, Yusuf, Yagci
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Diversity‐Oriented Syntheses by Combining CuAAC and Stereoselective INCIC Reactions with Peptides
Chemistry – A European Journal, 2017AbstractCascade reactions proceeding through peptide‐derived N‐carbamoyl iminium ions are reported. Two new reactions of N‐carbamoyl iminium ions are described, including a stereoselective double cyclization generating N,N′‐aminals and an acid‐promoted auto‐oxidation.
Yuanyuan Wang +3 more
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Effects of a Flexible Alkyl Chain on a Ligand for CuAAC Reaction
Organic Letters, 2010Imidazole derivatives substituted by a normal alkyl group are shown to be efficient as a ligand for the copper(Ι)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction. An alkyl chain on the imidazole ligands shows an efficient steric effect and benefits the reaction.
Asano, Keisuke, Matsubara, Seijiro
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