Results 51 to 60 of about 20,694 (254)

Cucumber-Derived Nanovesicles Containing Cucurbitacin B for Non-Small Cell Lung Cancer Therapy

open access: yesInternational Journal of Nanomedicine, 2022
Purpose In recent years, a variety of nanoparticles with excellent anticancer and delivery properties have emerged for cancer therapy. However, potential toxicity, high production cost and complex preparation procedures have been obstacles to their use ...
Tingting Chen   +10 more
semanticscholar   +1 more source

Cytotoxic Effect of Freeze-Dried Extract of Ecballium elaterium Fruit on Gastric Adenocarcinoma (AGS) and Esophageal Squamous Cell Carcinoma (KYSE30) Cell Lines [PDF]

open access: yes
Purpose Ecballium elaterium (L.) A. Rich (Cucurbitaceae), also known as the “squirting cucumber,” is a wild medicinal plant found abundantly in Moghan, Ardabil province, Iran.
بهلولی, شهاب   +2 more
core   +1 more source

Pharmacokinetics and Biological Activity of Cucurbitacins

open access: yesPharmaceuticals, 2022
Cucurbitacins are a class of secondary metabolites initially isolated from the Cucurbitaceae family. They are important for their analgesic, anti-inflammatory, antimicrobial, antiviral, and anticancer biological actions. This review addresses pharmacokinetic parameters recently reported, including absorption, metabolism, distribution, and elimination ...
Eugenia Elisa Delgado-Tiburcio   +6 more
openaire   +3 more sources

Nano-selenium enhances the antioxidant capacity, organic acids and cucurbitacin B in melon (Cucumis melo L.) plants.

open access: yesEcotoxicology and Environmental Safety, 2022
Pesticides are widely used in melon production causing safety issues around the consumption of melon and increasing pathogen and insect tolerance to pesticides.
Lu Kang   +6 more
semanticscholar   +1 more source

Cucurbitacin B induces ferroptosis in oral leukoplakia via the SLC7A11/mitochondrial oxidative stress pathway.

open access: yesPhytomedicine
BACKGROUND Oral leukoplakia (OLK), characterized by abnormal epithelial hyperplasia, is the most common precancerous oral mucosa lesion and is closely related to oxidative stress.
Mengyuan Yang   +9 more
semanticscholar   +1 more source

Cucurbitacin I inhibits the proliferation of pancreatic cancer through the JAK2/STAT3 signalling pathway in vivo and in vitro

open access: yesJournal of Cancer, 2022
Pancreatic cancer is one of the most aggressive solid malignancies, as it has a 5-year survival rate of less than 10%. The growth and invasion of pancreatic cancer cells into normal tissues and organs make resection and treatment difficult.
Dongchao Xu   +4 more
semanticscholar   +1 more source

Grayanotoxin I Intoxication in Pet Pigs [PDF]

open access: yes, 2018
Contaminated honey is a common cause of grayanotoxin intoxication in humans. Intoxication of animals, especially cattle, is usually due to ingestion of plants of the Ericaceae family, such as Rhododendron. Here, we report the ingestion of Pieris japonica
Köster, Nils   +5 more
core   +1 more source

Cucurbitacins as kairomones for diabroticite beetles [PDF]

open access: yesProceedings of the National Academy of Sciences, 1980
The characteristic bitter substances of the Cucurbitaceae act as kairomones for a large group of diabroticite beetles (Chrysomelidae, Galerucinae, Luperini), promoting host selection and compulsive feeding behavior. These beetles (e.g., Diabrotica undecimpunctata howardi ) respond to as little as 1 ng of ...
R L, Metcalf, R A, Metcalf, A M, Rhodes
openaire   +2 more sources

Pentacyclic and hexacyclic cucurbitacins from Elaeocarpus petiolatus

open access: yesPhytochemistry, 2022
Four undescribed cucurbitacins, designated as petiolaticins A-D, and four known cucurbitacins were isolated from the bark and leaves of Elaeocarpus petiolatus (Jack) Wall. Their chemical structures were elucidated based on detailed analyses of the NMR and MS data.
Eun-Seon Cho   +8 more
openaire   +2 more sources

Cucurbitacins: A Focus on Cucurbitacin E As A Natural Product and Their Biological Activities [PDF]

open access: yesPharmaceutical Sciences, 2020
For the last years, different types of cucurbitacins have been extracted from various species of Cucurbitaceae family. For this review, all related papers were accumulated by searching electronic databases in the English language, including PubMed, Scopus, and Google Scholar. The keywords of cucurbitacin, cucumber anticancer therapy, cytotoxic effects,
Moazzameh Ramezani   +3 more
openaire   +2 more sources

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