Results 41 to 50 of about 15,621 (174)

Cucurbitacins in plant food

, 2006
Poisoning due to Cucurbitaceous vegetables seems to be linked to intake of immensely bitter vegetables. The bitter and toxic compounds in these vegetables are cucurbitacins, which are well known in wild varieties of these food plants and their related species. The cultivated forms, on the other hand, have during cultivation been selected for being free
Gry, Jørn, Søborg, Inge, Christer Andersson, Hans   +2 more
openaire   +3 more sources

Quantification of cucurbitacins B and E in Coccinia grandis fruit ethanolic extract and their anti-inflammatory effects in SARS-CoV-2 protein-stimulated macrophages

Cogent Food & Agriculture
Food-derived bioactive compounds are increasingly being recognized for their potential in modulating inflammatory responses associated with post-infectious health conditions.
Rattanathorn Choonong, Laddawan Senggunprai, Waraporn Putalun, Waranyoo Phoolcharoen   +3 more
doaj   +1 more source

Recent Advances in the Application of Cucurbitacins as Anticancer Agents

Metabolites, 2023
Cucurbitacins are tetracyclic triterpenoid secondary metabolites, widely distributed in the Cucurbitaceae family. These bitter-tasting compounds act primarily as defense mechanisms against external injuries, and thus against herbivores, and furthermore ...
Bartłomiej Zieniuk, Magdalena Pawełkowicz   +1 more
doaj   +1 more source

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

Advanced Science, Volume 13, Issue 24, 27 April 2026.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu, Mei Liu, Changxing Gao, Cheng Zhao, Feijie Zhao, Shuqing Dong, Bo Zhang, Qianmei Liu, Wenqian Zhang, Ming Zhao, Qianjin Lu   +10 more
wiley   +1 more source

Cucurbitacins B, E and I Concentrations and Relationship with Drought Tolerance in Bottle Gourd [Lagenaria siceraria (Molina) Standl.]

Plants, 2023
Bottle gourd [Lagenaria siceraria (Molina) Standl.]) is a relatively drought-tolerant cucurbit due to the high composition of unique biochemical compositions, including cucurbitacin.
Phumzile Mkhize, Hussein Shimelis, Jacob Mashilo   +2 more
doaj   +1 more source

Identification of Blood Pressure‐Associated Metabolites by Integrating Metabolomic and Genetic Analysis

MedComm, Volume 7, Issue 4, April 2026.
This study identified 10 potential causality between metabolites and blood pressure and found potential genetic regulators of two metabolites. Multiomics integration revealed that a genetic variant near the omega‐3 metabolism genes (FADS1/FADS2) may influence blood pressure regulation by modulating prostaglandin E3 levels.
Yuanjiao Liu, Chunxiao Cheng, Xiong‐Fei Pan, Wei Shao, Dan Zhou, Yimin Zhu   +5 more
wiley   +1 more source

Cucurbitacin B inhibits proliferation, induces G2/M cycle arrest and autophagy without affecting apoptosis but enhances MTT reduction in PC12 cells

Bangladesh Journal of Pharmacology, 2015
In the present study, the effect of cucurbitacin B (a natural product with anti-cancer effect) was studied on PC12 cells. It significantly reduced the cell number, changed cell morphology and inhibited colony formation while MTT results showed increased ...
Chuanhong Wu, Jiaolin Bao, Chengwei He, Jinjian Lu, Xiuping Chen   +4 more
doaj  

n-Hexane Fraction of Cucumis melo L. Cultivar Gama Melon Parfum: An in vitro Study in MCF7 and T47D Cells Line

MCBS (Molecular and Cellular Biomedical Sciences)
Background: Cucumis melo a melon species, typically has a sweet taste. Some cultivars are known for their distinctive bitter flesh due to its higher levels of cucurbitacin. Cucurbitacin is semipolar compound that has anticancer properties.
Rohmi Salamah, Nastiti Wijayanti, Slamet Widiyanto   +2 more
doaj   +1 more source

Doxorubicin has a synergistic cytotoxicity with cucurbitacin B in anaplastic thyroid carcinoma cells

Tumor Biology, 2017
In this study, the combined effect of doxorubicin with cucurbitacin B on survival of anaplastic thyroid carcinoma cells was evaluated. For experiments, 8505C and CAL62 human anaplastic thyroid carcinoma cells were used.
Si Hyoung Kim, Jun Goo Kang, Chul Sik Kim, Sung-Hee Ihm, Moon Gi Choi, Hyung Joon Yoo, Seong Jin Lee   +6 more
doaj   +1 more source

Responses of Diabrotica speciosa to a semiochemical trap characteristics

Brazilian Archives of Biology and Technology, 2006
Responses of Diabrotica speciosa (Germar) (Coleoptera: Chrysomelidae) to a semiochemical trap characteristics were investigated in the field. The trap consisted of plastic bottles with several perforations (0.5 cm diameter and 2.0 cm distance each other)
Iara Cintra de Arruda-Gatti, Flávia Augusta Cloclet da Silva, Maurício Ursi Ventura   +2 more
doaj   +1 more source