Results 41 to 50 of about 14,776 (215)

Highly Oxygenated Triterpenoids and Diterpenoids from Fructus Rubi (Rubus chingii Hu) and Their NF-kappa B Inhibitory Effects

Molecules, 2021
During a phytochemical investigation of the unripe fruits of Rubus chingii Hu (i.e., Fructus Rubi, a traditional Chinese medicine named “Fu-Pen-Zi”), a number of highly oxygenated terpenoids were isolated and characterized.
Jiang Wan, Xiao-Juan Wang, Nan Guo, Xi-Ying Wu, Juan Xiong, Yi Zang, Chun-Xiao Jiang, Bing Han, Jia Li, Jin-Feng Hu   +9 more
doaj   +1 more source

Anti-Cancer Effect of Sesquiterpene and Triterpenoids from Agarwood of Aquilaria sinensis

Molecules, 2022
Two new guaiane sesquiterpenes, aquisinenoids A and B (1 and 2), two new eudesmane-type sesquiterpenoids, aquisinenoids C and D (3 and 4), one new cucurbitacin, aquisinenoid E (5), and five known cucurbitacins (6–10) were isolated from agarwood of ...
Lili Chen, Yunyun Liu, Yifei Li, Wu Yin, Yongxian Cheng   +4 more
doaj   +1 more source

Bitter Melon (Momordica charantia) Extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in Ovarian Cancer Cells Through Targeting AMPK Signaling Cascade [PDF]

, 2016
OBJECTIVE: Acquired chemoresistance is a major obstacle in the clinical management of ovarian cancer. Therefore, searching for alternative therapeutic modalities is urgently needed.
Al Rawahi T, D. Grahame Hardie, David W. Chan, Ferla R, Fiona A. Ross, Hextan Y. S. Ngan, Jinbiao Zhan, Kikkawa F, Limtrakul P, Mingo M. H. Yung, Pinto AL, Teh MT, Thomas H. Y. Leung   +12 more
core   +3 more sources

Hepatoprotective Activity of Ethanol Extract of Rice Solid-State Fermentation of Ganoderma tsugae against CCl₄-Induced Acute Liver Injury in Mice

Molecules, 2022
Ganoderma tsugae is well known as a medicinal mushroom in China and many Asian countries, while its fermentation technique and corresponding pharmacological activity are rarely reported. In this study, a wild G. tsugae strain (G42) with high triterpenoid
Xin Zhang, Wentao Lv, Yongping Fu, Yu Li, Jinhe Wang, Dongjie Chen, Xuerong Han, Zhenhao Li   +7 more
doaj   +1 more source

A Systematic Review of Iran’s Medicinal Plants With Anticancer Effects [PDF]

, 2015
Increase in cases of various cancers has encouraged the researchers to discover novel, more effective drugs from plant sources. This study is a review of medicinal plants in Iran with already investigated anticancer effects on various cell lines.
Asadi-Samani, Majid., Aslani, Elahe., Kooti, Wesam., shirzad, Hedayatollah.   +3 more
core   +1 more source

Targeting tumor-associated macrophages by anti-tumor Chinese materia medica [PDF]

, 2017
Tumor-associated macrophages (TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on ...
A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Saccani, A Schmieder, A Sica, A Sica, B Ruffell, B Shao, BB Aggarwal, BC Kennedy, BK Sekhon, C Jia, C Liu, C Steidl, CE Lewis, CK Mueller, Curzio Rüegg, D Ghosh, DM Mosser, E Bolli, E Schutyser, F Li, F Zhao, FO Martinez, FR Zhao, G Shu, G Solinas, H Diao, H Fritz, H Kurahara, H Kurahara, H Ouyang, H Wang, H Wang, H Zhang, H Zhao, HYT Nguyen, IA Schepetkin, J Cook, J Deng, J Ding, J Gao, J Li, J Li, J Li, J Rius, J Wang, J Yin, J Zhang, JB Mitchem, JW Pollard, JY Jang, JY Shin, Kun Zhou, L Bingle, L Sanchez-Martin, L Varinska, LI Partecke, Li-kang Sun, Lin Miao, M Egeblad, M Hong, M Ito, M Jinushi, M Pesic, MA Khan, Margaret Gebauer, Micheal O. Hottiger, ML Taddei, MR Galdiero, Muriel Cuendet, MY Kim, P Allavena, P Suboj, P Sun, P Yu, PS Kyrn, Q Dong, Q Lin, R Graziose, R Noy, R Ostuni, R Zhu, S Banerjee, S Gao, S Iwanowycz, S Lunardi, S Shi, S Shimura, S Ye, SM Woo, SR Hingorani, SR Hyam, T Kawanishi, T Xu, V Riabov, W Lam, W Shi, Wei-ling Pu, X Jia, X Li, X Lin, X Nie, X Qian, X Sun, X Tang, X Wang, X Zhan, X Zhang, X Zhang, Xiu-mei Gao, XL Zhu, XW Yang, Y Cai, Y Kimura, Y Lei, Y Liu, Y Song, Y Tu, Y Wang, Y Wang, Y Zhao, YP Guo, Yun-sha Zhang, Z Cai, Z Jiang, Z Lin, Z Liu   +131 more
core   +1 more source

Aquilaria sinensis: An Upstart Resource for Cucurbitacin Production Offers Insights into the Origin of Plant Bitter (Bi) Gene Clusters

Plants
Cucurbitacins, oxygenated tetracyclic triterpenoids that are found mainly in the Cucurbitaceae family, play essential roles as defensive compounds, serving as allomones against herbivores and pathogens and as signals for insect–parasite recognition ...
Xupo Ding, Zhuo Yang, Hao Wang, Jun Zeng, Haofu Dai, Wenli Mei   +5 more
doaj   +1 more source

Obtain Cucurbitacin from Ecballium elaterium and Cucurbita pepo and Converting into a Pharmaceutical Form

Journal of Food and Pharmaceutical Sciences, 2019
The squirting cucumber plant is widely used in the treatment of sinusitis, rheumatism, and hepatitis.It is reported that the liquid obtained from fruits is widely used in the treatment of sinusitis among people, especially in Turkey.
Derya Duran
doaj   +1 more source

Vaccarin Improves Myocardial Ischemia–Reperfusion Injury by Attenuating Oxidative Stress and Ferroptosis Through Reducing NOX4‐Modulated JAK2/STAT3 Pathway Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Vaccarin is a naturally occurring flavonoid glycoside with cardioprotective properties; however, its involvement in myocardial ischemia–reperfusion (MI/R) injury remains poorly defined. We herein investigated whether vaccarin protects cardiomyocytes from MI/R‐induced dysfunction in vivo and in vitro and examined the associated molecular ...
Han Yang, Mi Zhou, Feng‐Cai Zhang
wiley   +1 more source

Cucurbitacin E inhibits the Yes‑associated protein signaling pathway and suppresses brain metastasis of human non‑small cell lung cancer in a murine model. [PDF]

, 2019
Human non‑small cell lung cancer (NSCLC) is associated with an extremely poor prognosis especially for the 40% of patients who develop brain metastasis, and few treatment strategies exist.
Hsu, Ping-Chih, Jablons, David M, Liu, Shu, Tian, Bo, Urisman, Anatoly, Wang, Yu-Cheng, Xu, Zhidong, Yang, Cheng-Ta, Yang, Yi-Lin, You, Liang   +9 more
core