Results 61 to 70 of about 14,776 (215)

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor, Kavita Verma, Nishu, Barkat Hussain, Vartika Mathur   +4 more
wiley   +1 more source

Primary Human Macrophages Serve as Vehicles for Vaccinia Virus Replication and Dissemination [PDF]

, 2014
Human monocytic and professional antigen-presenting cells have been reported only to exhibit abortive infections with vaccinia virus (VACV). We found that monocyte-derived macrophages (MDMs), including granulocyte macrophage colony-stimulating factor (GM-
Amet, Tohti, Byrd, Daniel, Desai, Mona, Hu, Ningjie, Lan, Jie, Shepherd, Nicole, Yang, Kai, Yu, Qigui   +7 more
core   +1 more source

Reduction of Cancer Stem Cells and Invasiveness of Human Melanoma and Breast Cancer by Cucurbitacin B from Lagenaria siceraria

Drugs and Drug Candidates, 2023
Cucurbitacins are secondary metabolites that are commonly found in the Cucurbitacae family. Many biological properties have been reported for cucurbitacins, including anti-inflammatory, antioxidant, antiviral, anti-malaria, and anticancer properties ...
Cheng-Chen Huang, Kiera K. Balding, Sydney J. Zimmerman, Che-Yuan Chang, Si-Min Lu, Hui-Chi Huang   +5 more
doaj   +1 more source

Phytochemical Composition, Health Benefits, Functional Properties, and Food Applications of Pumpkin Seeds

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Pumpkin seeds (Cucurbita spp.) are rich in bioactive compounds including proteins, unsaturated fatty acids, dietary fiber, vitamins (E and B‐complex), minerals (zinc, magnesium, iron), and phytochemicals such as phenolics, flavonoids, and phytosterols.
Messenbet Geremew Kassa, Desye Alemu Teferi   +1 more
wiley   +1 more source

Antioxidants profile of Momordica charantia fruit extract analyzed using LC-MS-QTOF-based metabolomics

Food Chemistry: Molecular Sciences, 2021
Momordica charantia fruit is claimed to have healthy benefit. Despite this potential claim, the phytochemical study of this fruit is still lacking. Thus, this study aimed to evaluate the antioxidants profile of Momordica charantia (Cucurbitaceae) fruit ...
Vikneswari Perumal, Alfi Khatib, Qamar Uddin Ahmed, Bisha Fathamah Uzir, Faridah Abas, Suganya Murugesu, Mohd Zuwairi Saiman, Riesta Primaharinastiti, Hesham El-Seedi   +8 more
doaj   +1 more source

Viral Mechanisms and Drug Influences on Janus Kinase/Signal Transducers and Activators of Transcription (JAK/STAT) Pathway in Human Coronaviruses Infection: A Systematic Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aim Janus kinases/signal transducers and activators of transcription (JAK/STAT) pathway is crucial for various stages of immunity, from innate to adaptive responses. Type 1 IFNs activate JAK/STAT pathway by binding to receptors on JAK, phosphorylating STAT and upregulating interferon‐stimulated genes (ISGs) leading to cytokines ...
Esimebia Adjovi Amegashie, Ruth Oyawole Sikeola, Caleb Koranteng Kwayisi‐Darkwah, Gabriel Atampugbire, Emmanuel Ayitey Tagoe, Elijah Paintsil, Kwasi Torpey, Osbourne Quaye   +7 more
wiley   +1 more source

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

Advanced Science, Volume 13, Issue 24, 27 April 2026.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu, Mei Liu, Changxing Gao, Cheng Zhao, Feijie Zhao, Shuqing Dong, Bo Zhang, Qianmei Liu, Wenqian Zhang, Ming Zhao, Qianjin Lu   +10 more
wiley   +1 more source

Wild edible plants: Nutritional and toxicological characteristics, retrieval strategies and importance for today's society [PDF]

, 2017
Wild edible plants (WEPs) are part of the cultural and genetic heritage of different regions of the world. In times of famine and scarcity, these sources of nutrients and health-promoting compounds have received high importance mainly in rural and ...
Abbasi, Abdelli, Aceituno-Mata, Al-Qura'n, Alarcón, Amaducci, Amalraj, Amirul, Ana Maria Carvalho, Anderson, AOAC, Bacchetta, Baker, Barreira, Barros, Barros, Barros, Barros, Barros, Barros, Barros, Barros, Barros, Barroso, Bianco, Bicho, Brogren, Caldas, Caleja, Caleja, Caleja, Carocho, Carr, Carvalho, Carvalho, Carvalho, Castañeda-Álvarez, Chen, Chen, Chen, Costa, Cowan, Da Rocha, Dias, Dodson, EFSA, EFSA, EFSA, EMA, EMA, European Commission, Fajardo, Fernandes, Galli, García Herrera, García-Herrera, García-Herrera, García-Herrera, García-Jiménez, Gille, Glensk, Gry, Guerra, Guil, Guil-Guerrero, Guil-Guerrero, Guil-Guerrero, Guimarães, Gupta, Güçlü-Üstündağ, Hylands, Hylands, Isabel C.F.R. Ferreira, José Pinela, Kaur, Kaushik, Kemal, Kim, Kiuchi, Kovács, Kovács, Kristanc, Kristanc, Kumarasamy, Lee, Li, Liebman, Magos Brehm, Marostica, Martins, Martins, Martins, Mason, Maxted, Menendez-Baceta, Menendez-Baceta, Molina, Monzote, Morales, Morales, Morales, Morales, Morales, Morales, Muzquiz, Muñoz, Niki, Niki, Nikolić, Oda, Oliveira, Oobayashi, Ottaway, Otten, Palaniswamy, Pandey, Pardo-de-Santayana, Pereira, Pereira, Pereira, Petropoulos, Petropoulos, Pinela, Pinela, Pinela, Pinela, Pinela, Pinela, Pinela, Pinela, Podolak, Pohlmann, Quintaes, Radulović, Ranfa, Renna, Reyes-García, Roeder, Réthy, Saini, Schippmann, Simopoulos, Sinha, Smith, Smolarz, Smolin, Souci, Stein, Street, Swaminathan, Sánchez-Mata, Sánchez-Mata, Sõukand, Sõukand, Tardio, Tardío, Tardío, Tardío, Tardío, Teixeira, The European Parliment and the Council of the European Union, The Plant List, Thomassen, Torbati, Torija-Isasa, Trichopoulou, Tucker, Turner, Tuttolomondo, Vacillotto, Vasquez, Vermerris, Vermerris, Vinha, Vizgirdas, Wiedenfeld, Wretensjö, Wu, Zhang, Zhang, Zhao, Łuczaj, Łuczaj, Żołnierczyk   +183 more
core   +1 more source

In vitroandin vivoanticancer properties of cucurbitacin isolated fromCayaponia racemosa [PDF]

Pharmaceutical Biology, 2012
Cucurbitacins are a group of triterpenoids that have a cucurbitane skeleton with a wide range of biological activities.This study evaluated the anticancer properties of one cucurbitacin isolated from Cayaponia racemosa Cong. (Cucurbitaceae), 2β,3β,16α,20(R),25-pentahydroxy-22-oxocucurbita-5-en (1), with in vitro and in vivo models.In vitro cytotoxic ...
Gardenia C G, Militão, Ivana N F, Dantas, Paulo Michel P, Ferreira, Ana Paula N N, Alves, Davina C, Chaves, Francisco José Q, Monte, Cláudia, Pessoa, Manoel, Odorico de Moraes, Letícia V, Costa-Lotufo   +8 more
openaire   +2 more sources

Combination of 2 Bioactive Compounds for Treatment of Breast Cancer: Triterpenoid Cucurbitacin I and Phenolic CAPE

Natural Product Communications, 2019
It has been demonstrated that both cucurbitacin I (Cu I) and caffeic acid phenethyl ester (CAPE) have anticancer activities. The current study aimed to examine the proliferation, migration, and colony formation actions of Cu I and CAPE on MCF-7 and MDA ...
Fuat Karakuş, Kadir Yılmaz, Ergül Eyol, Songül Ünüvar   +3 more
doaj   +1 more source