Results 131 to 140 of about 3,713,706 (201)

N-acetylcysteine reduces prefrontal reactivity to cocaine cues in individuals with cocaine use disorder

Frontiers in Psychiatry
BackgroundIndividuals with cocaine use disorder experience heightened motivation to pursue rewards tied to cocaine, often triggered by associated cues.
Etna J. E. Engeli, Katrin H. Preller, Nathalie M. Rieser, Nathalie M. Rieser, Johanna Klar, Johanna Klar, Philipp Staempfli, Lea M. Hulka, Matthias Kirschner, Matthias Kirschner, Erich Seifritz, Erich Seifritz, Marcus Herdener   +12 more
doaj   +1 more source

ON-ICE trial: Investigation of the combined effects of oxytocin and naltrexone on stress-induced and alcohol cue-induced craving in alcohol use disorder-Study protocol of a phase II randomised double-blind placebo-controlled parallel-group trial. [PDF]

BMJ Open, 2022
Zimmermann S, Thomas BC, Krisam J, Limprecht R, Klose C, Stenger M, Pourbaix M, Ries M, Vollstaedt-Klein S, Koopmann A, Lenz B, Kiefer F, Bach P.   +12 more
europepmc   +1 more source

Parkinson's disease under dopamine replacement therapy as a human framework for studying addiction‐relevant mechanisms

Psychiatry and Clinical Neurosciences, Volume 80, Issue 11, Page 877-888, November 2026.
Addiction is a chronic relapsing condition characterized by compulsive reward seeking and impaired behavioral control, associated with major individual and societal burden. Mechanistic investigation in humans remains constrained by ethical limitations, uncontrolled exposure histories, and ecological confounds.
Vanessa Fleury, Elvira Pirondini, Damien Benis, Tiffany Corbet, Gabriel Thorens, Christian Lüscher, Paul Krack   +6 more
wiley   +1 more source

Gamified Adaptive Approach Bias Modification in Individuals With Methamphetamine Use History From Communities in Sichuan: Pilot Randomized Controlled Trial

JMIR Serious Games
BackgroundCognitive bias modification (CBM) programs have shown promise in treating psychiatric conditions, but they can be perceived as boring and repetitive.
Danlin Shen, Jianping Jiao, Liqun Zhang, Yanru Liu, Xiang Liu, Yuanhui Li, Tianjiao Zhang, Dai Li, Wei Hao   +8 more
doaj   +1 more source

Temporal Dynamics of Large-Scale Networks Predict Neural Cue Reactivity and Cue-Induced Craving. [PDF]

Biol Psychiatry Cogn Neurosci Neuroimaging, 2020
Wang KS, Kaiser RH, Peechatka AL, Frederick BB, Janes AC.   +4 more
europepmc   +1 more source

The Moderating Role of Sex in the Relation between Cue-Induced Craving and Resting-State Functional Connectivity in the Salience Network of Non-Clinically Diagnosed Drinkers.

Eur Addict Res, 2023
Firdaus I, Kleiboer AM, Huizink AC, Kaag AM.   +3 more
europepmc   +1 more source

Oxytocin increases neural cue-reactivity but modulates cue-induced craving differently in males and females with alcohol use disorder - results of a randomized controlled cross-over trial

Background Craving and altered reactivity to alcohol cues are central features of alcohol use disorder (AUD). Approved medications yield only limited effects on these facets. Oxytocin (OXY) might be a promising candidate, due to its anti-craving effects.
Falk Kiefer, Matthias Reichl, Rainer Spanagel, Lea Sirignano, Valery Grinevich, Patrick Bach, Anne Koopmann, Wolfgang Sommer, Sina Vetter   +8 more
core  

A case report illustrating the effects of repetitive transcranial magnetic stimulation on cue-induced craving in an individual with opioid and cocaine use disorder. [PDF]

Exp Clin Psychopharmacol, 2020
Mahoney JJ, Marshalek PJ, Rezai AR, Lander LR, Berry JH, Haut MW.   +5 more
europepmc   +1 more source

Stress-Induced Sensitization of Insula Activation Predicts Alcohol Craving and Alcohol Use in Alcohol Use Disorder

245255Background: Stress and alcohol cues trigger alcohol consumption and relapse in alcohol use disorder. However, the neurobiological processes underlying their interaction are not well understood.
Bekier, Nina Kim, Zimmermann, Sina, Langejürgen, Jens, Gerhardt, Sarah, Tost, Heike, Vollstädt-Klein, Sabine, Kirschbaum, Clemens, Berhe, Oksana, Gessner, Tatjana, Stallkamp, Jan L., Kiefer, Falk, Radler, Philipp, Lenz, Bernd, Zaiser, Judith, Hoffmann, Sabine, Abel, Martin, Bach, Patrick   +16 more
core   +1 more source

Mindfulness buffers the effects of cue-induced craving on alcohol demand in college drinkers. [PDF]

Addict Behav, 2018
Hochster A, Block-Lerner J, Marks DR, Erblich J.   +3 more
europepmc   +1 more source