Results 81 to 90 of about 3,713,706 (201)

Synaptic Depression Via Mglur1 Positive Allosteric Modulation Suppresses Cue-Induced Cocaine Craving [PDF]

, 2014
Cue-induced cocaine craving is a major cause of relapse in abstinent addicts. In rats, cue-induced craving progressively intensifies (incubates) during withdrawal from extended-access cocaine self-administration.
Wolf, Marina E, Olive, M, Kerstin A Ford, LaCrosse, Amber L, Eden Flores-Barrera, Olive, M Foster, Tseng, Kuei Y, Szumlinski, Karen K, Tuan Le, Li, Xuan, M Foster Olive, Andrew F Scheyer, Flores-Barrera, Eden, Ford, Kerstin, Kuei Y Tseng, Karen K Szumlinski, Scheyer, Andrew F, Loweth, Jessica A, Tseng, Kuei, Xuan Li, Milovanovic, Mike, Amber L LaCrosse, Ford, Kerstin A, Loweth, Jessica, Werner, Craig T, Wolf, Marina, Mike Milovanovic, Scheyer, Andrew, Craig T Werner, Marina E Wolf, Le, Tuan, LaCrosse, Amber, Szumlinski, Karen, Jessica A Loweth, Werner, Craig   +34 more
core   +1 more source

Effect of conditioned stimuli-triggered memory retrieval-extinction in patients with methamphetamine use disorder

Translational Psychiatry
Methamphetamine (METH) is a widely abused stimulant that affects the central nervous system. The persistent maladaptive conditioned stimuli (CS, drug cues)-drug associative memories represent a primary factor precipitating relapse.
Jing-Li Yue, Ru-Jia Wang, Si-Jing Chen, Xiao Lin, Qing Fang, Xiao-Jie Guo, Ye-Kun Sun, Kai Yuan, Yan-Ping Bao, Jie Shi, Yan-Xue Xue, Ping Wu, Lin Lu   +12 more
doaj   +1 more source

Cross‐sectional and longitudinal associations of cannabis use with cognitive functioning in individuals with a cannabis use disorder: The moderating role of nicotine

Addiction, EarlyView.
Abstract Background and Aims Cannabis is among the most widely used psychoactive substances globally and is often consumed alongside tobacco. Cannabis use has been associated with impairments in attention, learning, and memory, whereas nicotine can acutely enhance, but chronically impair, certain cognitive functions.
Emese Kroon, Nora de Bode, Karis Colyer‐Patel, Jia Hua Hsieh, Francesca Filbey, Janna Cousijn   +5 more
wiley   +1 more source

Drug-Induced Craving for Methamphetamine Is Associated With Neural Methamphetamine Cue Reactivity. [PDF]

, 2019
OBJECTIVE: Drug craving serves as the major motivator to propagate drug use and is thought to elicit relapse in abstinent individuals. Although craving for methamphetamine has been investigated using both laboratory and neuroimaging methodologies, the ...
Ray, Lara A, Courtney, Kelly E, Grodin, Erica N   +2 more
core   +1 more source

Psychological change processes in alcohol use disorder: A qualitative study of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) with cognitive behavioural therapy

Addiction, EarlyView.
Abstract Background and aims This study qualitatively explored psychological change processes as described by participants and therapists within a phase 2a clinical trial evaluating the safety, tolerability, and preliminary efficacy of a single dose of intranasal 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT; BPL‐003) administered alongside psychological
Mathieu Seynaeve, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, James J. Rucker, Anthony Cleare, John Marsden   +6 more
wiley   +1 more source

Magnitude and duration of cue-induced craving for marijuana in volunteers with cannabis use disorder. [PDF]

Drug Alcohol Depend, 2016
Evaluate magnitude and duration of subjective and physiologic responses to neutral and marijuana (MJ)-related cues in cannabis dependent volunteers.33 volunteers (17 male) who met DSM-IV criteria for Cannabis Abuse or Dependence were exposed to neutral (first) then MJ-related visual, auditory, olfactory and tactile cues.
Lundahl LH, Greenwald MK.
europepmc   +4 more sources

Towards the implementation of cannabis‐focused apps in early intervention services for psychosis: A qualitative investigation of patient and clinician perspectives

Addiction, EarlyView.
Abstract Background and aims Cannabis use is highly prevalent among young adults with first‐episode psychosis (FEP) and is associated with poorer clinical and functional outcomes. Mobile health interventions may help address structural barriers to delivering cannabis‐focused psychosocial interventions within early intervention services (EIS), yet ...
Selim Abou‐Rahal, Alexis Doucet, Pamela Lachance‐Touchette, Amal Abdel‐Baki, Stephanie Coronado‐Montoya, José Côté, Ovidiu Tatar, Philip G. Tibbo, Didier Jutras‐Aswad   +8 more
wiley   +1 more source

Effects of Repeated Cue Exposure on Cannabis Craving [PDF]

, 2015
Craving is a key element of the cannabis withdrawal syndrome that has been associated with continued use and relapse. Although cue-induced cannabis craving has been established in single laboratory sessions, procedures to sustain craving over multiple ...
Fogel, Jessica S
core  

Clinical features of mental imagery in substance use disorders: A mixed‐methods analysis

Addiction, EarlyView.
Abstract Aims To characterise the frequency, features and content of craving‐related mental imagery among people seeking treatment for substance use disorders (SUDs); examine within‐session change in self‐reported craving following imagery elicitation; and explore perceived links with autobiographical memory, behavioural, cognitive and emotional ...
Gemma Scott, Tim Meynen, Francesca Small, Luke Mitcheson, Elizabeth Appiah‐Kusi, William Barber, Colette Hirsch, John Marsden   +7 more
wiley   +1 more source

Acupuncture inhibits cue-induced heroin craving and brain activation.

Neural regeneration research, 2012
Previous research using functional MRI has shown that specific brain regions associated with drug dependence and cue-elicited heroin craving are activated by environmental cues. Craving is an important trigger of heroin relapse, and acupuncture may inhibit craving. In this study, we performed functional MRI in heroin addicts and control subjects.
Cai, Xinghui, Song, Xiaoge, Li, Chuanfu, Xu, Chunsheng, Li, Xiliang, Lu, Qi   +5 more
openaire   +2 more sources