Results 61 to 70 of about 138,952 (282)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

REsearch into implementation STrategies to support patients of different ORigins and language background in a variety of European primary care settings (RESTORE): study protocol

Implementation Science, 2012
Background The implementation of guidelines and training initiatives to support communication in cross-cultural primary care consultations is ad hoc across a range of international settings with negative consequences particularly for migrants.
MacFarlane Anne, O’Donnell Catherine, Mair Frances, O’Reilly-de Brún Mary, de Brún Tomas, Spiegel Wolfgang, van den Muijsenbergh Maria, van Weel-Baumgarten Evelyn, Lionis Christos, Burns Nicola, Gravenhorst Katja, Princz Christine, Teunissen Erik, van den Driessen Mareeuw Francine, Saridaki Aristoula, Papadakaki Maria, Vlahadi Maria, Dowrick Christopher   +17 more
doaj   +1 more source

Ambiguous Bodies, Biopower and the Ideologies of Science Fiction [PDF]

, 2016
Contemporary Hollywood film narrates the fear of monstrous science; attending to the modulations of medicine, capital and the body. The filmic body is employed to illustrate the power of the new biotechnologies to create and sustain life and the new ...
Flynn, Susan
core  

Export Price Stability and Compatibility of Euro under the Export- Biased Productivity Growth in Turkey: A Criticism against the Maastricht Inflation Criterion [PDF]

, 2014
In this work, we analyzed the export- biased productivity, wage growth and the ULCP in Turkey. Then, by using input- output methods , we could show that Turkey has an economy which is able to be a part of the Euro system and Euro is compatible under the ...
ÜNAL, Emre
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Web-Based Visualization of Very Large Scientific Astronomy Imagery [PDF]

, 2015
Visualizing and navigating through large astronomy images from a remote location with current astronomy display tools can be a frustrating experience in terms of speed and ergonomics, especially on mobile devices.
Bertin, Emmanuel, Marmo, Chiara, Pillay, Ruven   +2 more
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Perceptions of sexual violence among adolescents and youth in Senegal and Ghana: Insights into normalization, victim-blaming and prospective behavior

Global Public Health
This study explores the perceptions of adolescents (10−19 years) and youth (20−24) toward sexual violence in Senegal and Ghana, their attitudes, and expected behaviors when witnessing such violence.
Charlotte J. W. van Tuijl, Anke van der Kwaak, John K. Krugu, El Hadji Mamadou Ndiaye   +3 more
doaj   +1 more source

Tissue Culture of Normal Rat Glomeruli

Kidney and Blood Pressure Research, 1980
The biosynthesis of glycosaminoglycans (GAG) by cultivated rat glomerular epithelial and mesangial cells was studied by incorporation of [³⁵S] sulfate or [¹⁴C] glucosamine for 48 h. After dialysis, the incubation medium was subjected to digestion with papain.
J.B. Foidart, Y.S. Pirard, R.J. Winand, P.R. Mahieu   +3 more
openaire   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source