Results 101 to 110 of about 6,992,473 (362)

Harnessing the landscape of microbial culture media to predict new organism–media pairings

Nature Communications, 2015
Culturing microorganisms is a critical step in understanding and utilizing microbial life. Here we map the landscape of existing culture media by extracting natural-language media recipes into a Known Media Database (KOMODO), which includes >18,000 ...
M. Oberhardt, Raphy Zarecki, S. Gronow, E. Lang, H. Klenk, U. Gophna, E. Ruppin   +6 more
semanticscholar   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Slow Religion: Literary Journalism as a Tool for Interreligious Dialogue

Religions, 2019
Intercultural and interfaith dialogue is one of the challenges faced by society. In a world marked by globalisation, digitisation, and migratory movements, the media is the agora for people of different faiths and beliefs.
Alba Sabaté Gauxachs, Josep Lluís Micó Sanz, Míriam Díez Bosch   +2 more
doaj   +1 more source

Benchmarking of commercially available CHO cell culture media for antibody production

Applied Microbiology and Biotechnology, 2015
In this study, eight commercially available, chemically defined Chinese hamster ovary (CHO) cell culture media from different vendors were evaluated in batch culture using an IgG-producing CHO DG44 cell line as a model.
D. Reinhart, L. Damjanovic, C. Kaisermayer, R. Kunert   +3 more
semanticscholar   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Characterization of microRNA in bovine in vitro culture media associated with embryo quality and development.

Journal of Dairy Science, 2015
Dairy cattle fertility has declined over time due to factors including reduced fertilization and early embryonic loss. To counter fertility problems and better study preimplantation embryonic development, in vitro production systems have been developed ...
Jenna Kropp, H. Khatib
semanticscholar   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source

The Politics of Disconnective Media: Unraveling the Materiality of Discourses on Disconnectivity

Media and Communication
The commodification of disconnection has attracted growing scholarly attention. Previous research highlighted the instrumentalisation of disconnection for productivity, self-governance, and healthy life. Researchers have also explored the politics of the
Veysel Bozan, Emiliano Treré
doaj   +1 more source

The cytochrome oxidase defect in ISC‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm22

FEBS Letters, EarlyView.
The yeast mitoribosome assembly factor Rsm22 contains a [4Fe‐4S] cluster that is matured by the mitochondrial iron–sulfur cluster assembly (ISC) machinery. Defects in ISC components result in impaired mitochondrial protein synthesis due to a mitoribosome assembly defect.
Ulrich Mühlenhoff, Dominik Trauth, Weronika Śliwińska, Linda Boss, Roland Lill   +4 more
wiley   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source