Results 101 to 110 of about 3,578,819 (354)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Media Philosophy— A Reasonable Programme? [PDF]

open access: yes, 2008
It is beyond any doubt that media have an enormous impact on our media-culture societies. Media in?uence our perception and our knowledge, our memory as well as our emotions. They create public spheres and public opinions and give rise to media realities.
Schmidt, Siegfried J.
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Rapid metabolism of exogenous angiotensin II by catecholaminergic neuronal cells in culture media [PDF]

open access: gold, 2015
Urmi Basu   +5 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

DECONSTRUCTION OF IDEOLOGICAL HEGEMONY OF LANGUAGE-CULTURE MAINTENANCE IN SUNDANESE MEDIA [PDF]

open access: yes, 2012
The media, a controlling discourse, is presupposed to perform social power of groups that have ability to control the minds of other groups. The practice of this mind control involves more than acquiring beliefs.
Sari , Retno Purwani
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Postcolonial Intellectuals: Exploring Belonging Across Borders in Igiaba Scego’s La mia casa è dove sono (My Home Is Where I Am)

open access: yesSocial Sciences
This article focuses on the life writing narratives of diasporic writers in Europe, such as the Italian writer of Somali descent Igiaba Scego, who, through her writing and public role, manages to create powerful interventions on issues of belonging ...
Sandra Ponzanesi   +1 more
doaj   +1 more source

These are the echoes: Sound Proof 2008-2012 [PDF]

open access: yes, 2013
Article in peer-reviewed journal Culture/Kultura for their thematic issue, Art Media and Cultural Memory.
Biagioli, Monica
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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