Results 51 to 60 of about 217,978 (314)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

PARATUBERCULOSIS AND FOOD OF ANIMAL ORIGIN

Italian Journal of Food Safety, 2013
Mycobacterium avium ssp. paratubercolosis (MAP) is the causative agent of Johne’s disease (or paratubercolosis),a chronic infectious enteritis in cattle, sheep and goats. Infected animals shed viable MAP in their milk, faeces and semen.
T.A. Sarli, E. Sarno
doaj   +1 more source

Bioprospecting of Lactobacillus sp. Starter Culture from Colostrum Breast Milk for Probiotic Milk Production from Soybeans

JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS, 2023
Lactobacillus sp. is a bacterium that naturally exists in various environments, including in breast milk colostrum. This bacterium belongs to a group of lactic acid bacteria that produce lactic acid as the main product of sugar fermentation so that it has probiotic properties that also play a role in the fermentation process. This study aims to produce
Mufti Hatur Rahmah, Masriany Masriany, Ramlah Ramlah, Isdaryanti Isdaryanti   +3 more
openaire   +1 more source

Features of the selection of starter cultures in the production of functional fermented milk products

Vestnik MGTU, 2023
Modern trends in the formation of a healthy lifestyle have led to the active development of technologies for the production of functional fermented milk products. The selection of a rational combination of lactic acid bacteria and bifidobacteria for creating starter cultures should provide products with functional properties and take into account the ...
M. S. Kanochkina, L. A. Ivanova, A. D. Konovalova, O. N. Levin   +3 more
openaire   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

The Detection of Methicillin and Multiple Antibiotics Resistant Staphylococcus aureus in Dairy Products as Sold in Parts of Kaduna State, Nigeria

UMYU Journal of Microbiology Research
Dairy products sold through unregulated channels are potential sources of a variety of microorganisms that are involved in food poisoning.  Staphylococcus aureus is a known example of bacteria causing food-borne diseases.
Okpo, N. O., Abdullahi, I. O., Alalade, O. M., Madubuike, S. A.   +3 more
doaj   +1 more source

Hygienic and Physico- Chemical Quality of Local Milk and Milk Products Sold in Milk Bars in Chad

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2007
The objective of this study was to assess the quality of local, whole, and fermented milk produced in the milk bars of N’Djamena, where the demand for dairy products is increasing.
M. O. Koussou, P. Grimaud, L. Y. Mopaté
doaj   +1 more source

Milk Protein-Derived Antioxidant Tetrapeptides as Potential Hypopigmenting Agents

Antioxidants, 2020
Excessive accumulation of melanin can cause skin pigmentation disorders, which may be accompanied by significant psychological stress. Although many natural and synthetic products have been developed for the regulation of melanogenesis biochemistry, the ...
Saerom Kong, Hye-Ryung Choi, Yoon-Jeong Kim, Yoon-Sik Lee, Kyoung-Chan Park, Seon-Yeong Kwak   +5 more
doaj   +1 more source

STARTER CULTURES COMPOSITIONS WITH PROBIOTICS FOR FERMENTED MILK PRODUCTS AND COSMETICS

Food Science and Technology, 2018
The expediency of optimization of starter cultures composition of mixed cultures Lactococcus sp. and mixed cultures Bifidobacterium bifidum BB 01 + Bifidobacterium longum BL 01 + Bifidobacterium breve BR 01 for the manufacture of fermented milk products and cosmetics for teenagers and people under the age of 40-45 years with probiotics has been ...
N. Tkachenko, Ju. V. Nazarenko, N. Dets, E. Izbash, I. Klymentieva   +4 more
openaire   +2 more sources