Results 71 to 80 of about 211,499 (306)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Dominant Lactic Acid Bacteria in Naturally Fermented Milks from Messinese Goat’s Breed

Journal of Food Quality and Hazards Control, 2019
Background: Lactic Acid Bacteria (LAB) are an important group of microorganisms responsible for the fermentation dairy products. This study was done to identify the dominant lactic acid bacteria in naturally fermented milks from Messinese goat’s breed ...
M. Palmeri, I. Mancuso, P. Barbaccia, F. Cirlincione, M.L. Scatassa   +4 more
doaj  

Biotechnological applications of functional metagenomics in the food and pharmaceutical industries [PDF]

, 2015
peer-reviewedMicroorganisms are found throughout nature, thriving in a vast range of environmental conditions. The majority of them are unculturable or difficult to culture by traditional methods.
Alvarez-Ordonez, Avelino, Cotter, Paul D., Coughlan, Laura M., Hill, Colin   +3 more
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Current status and challenges for cell-cultured milk technology: a systematic review

Journal of Animal Science and Biotechnology
Cellular agriculture is an innovative technology for manufacturing sustainable agricultural products as an alternative to traditional agriculture. While most cellular agriculture is predominantly centered on the production of cultured meat, there is a ...
Hyuk Cheol Kwon, Hyun Su Jung, Vahinika Kothuri, Sung Gu Han   +3 more
doaj   +1 more source

Benefits and risks of the hormetic effects of dietary isothiocyanates on cancer prevention [PDF]

, 2014
The isothiocyanate (ITC) sulforaphane (SFN) was shown at low levels (1-5 µM) to promote cell proliferation to 120-143% of the controls in a number of human cell lines, whilst at high levels (10-40 µM) it inhibited such cell proliferation.
A Arlt, A Giudice, A Herman-Antosiewicz, A Lau, A Lister, A Melchini, A Speciale, AA Alfadda, AJ Vargas, AT Dinkova-Kostova, AV Gasper, C Cornelius, C Fimognari, C Fimognari, Changhao Sun, CR Zhao, D Li, D Rand, D Ren, Daotai Nie, DD Zhang, DS Michaud, E Warwick, EJ Calabrese, EJ Calabrese, EJ Calabrese, EJ Calabrese, ER Hahm, F Ekiz, F Galgano, F Zanichelli, GM DeNicola, GR Fenwick, GS Omenn, HK Na, I Misiewicz, I Oehme, IS Santos, J Jakubikova, J Watson, JD Clarke, JD Hayes, JD Watson, JM Cramer, K Pietsch, K Suppipat, KA Moy, KL Cheung, L Gamet-Payrastre, L Kuang, L Ye, LN Barrera, LS Cooley, M McMahon, MB Sporn, MP Mattson, MP Mattson, P Sestili, P Shelton, PE Miller, R Brigelius-Flohe, RF Clayton, RK Thimmulappa, S Homma, SA McNaughton, SJ Jackson, SL Navarro, T Hara, T Nishikawa, T Xu, TG Son, TW Kensler, TW Kensler, V Calabrese, V Rungapamestry, W Hendrickx, Wei Wang, X Ma, X Yu, XJ Wang, Y Ji, Y Li, Y Mitsuishi, Y Shan, Y Zhang, Y Zhang, Y Zhang, Y Zhang, YJ Surh, Yongping Bao, YS Keum, Zhigang Zhou   +91 more
core   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Spectral tracing of deuterium for imaging glucose metabolism. [PDF]

, 2019
Cells and tissues often display pronounced spatial and dynamical metabolic heterogeneity. Common glucose-imaging techniques report glucose uptake or catabolism activity, yet do not trace the functional utilization of glucose-derived anabolic products ...
Liu, Yinong, Miao, Yupeng, Min, Wei, Qian, Naixin, Shen, Yihui, Shi, Lingyan, Wei, Mian, Zhang, Luyuan   +7 more
core  

Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]

, 2010
Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel, Brimacombe, Claire L, Cao, Feng, Graf, Tyler N, Grove, Joe, Kane, Olivia J, Lohmann, Volker, Martinez, Laura E, McKeating, Jane A, Nahmias, Yaakov, Negash, Amina, Oberlies, Nicholas H, Owen, David M, Polyak, Stephen J, Pécheur, Eve-Isabelle, Tavis, John E, Wagoner, Jessica   +16 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source