Results 41 to 50 of about 213,267 (396)

Curcumin Prevents Acute Neuroinflammation and Long-Term Memory Impairment Induced by Systemic Lipopolysaccharide in Mice [PDF]

open access: yes, 2018
Systemic lipopolysaccharide (LPS) induces an acute inflammatory response in the central nervous system (CNS) (\u201cneuroinflammation\u201d) characterized by altered functions of microglial cells, the major resident immune cells of the CNS, and an ...
Confortin, Francesca   +7 more
core   +5 more sources

Natural Deep Eutectic Solvents as Agents for Improving Solubility, Stability and Delivery of Curcumin [PDF]

open access: yesJP. Pharm Res (2019) 36: 116, 2019
Purpose Study on curcumin dissolved in natural deep eutectic solvents (NADES) was aimed at exploiting their beneficial properties as drug carriers. Methods The concentration of dissolved curcumin in NADES was measured. Simulated gastrointestinal fluids were used to determine the concentration of curcumin and quantum chemistry computations were ...
arxiv   +1 more source

A novel diblock copolymer of (monomethoxy poly [ethylene glycol]-oleate) with a small hydrophobic fraction to make stable micelles/polymersomes for curcumin delivery to cancer cells [PDF]

open access: yes, 2014
Curcumin is a potent natural anticancer agent, but its effectiveness is limited by properties such as very low solubility, high rate of degradation, and low rate of absorption of its hydrophobic molecules in vivo.
Erfani-Moghadam, V.   +5 more
core   +2 more sources

The Essential Medicinal Chemistry of Curcumin

open access: yesJournal of Medicinal Chemistry, 2017
Curcumin is a constituent (up to ∼5%) of the traditional medicine known as turmeric. Interest in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led to their extensive investigation.
Kathryn M. Nelson   +5 more
semanticscholar   +1 more source

Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF-κB Suppression and NLRP3 Inflammasome Inhibition

open access: yesOxidative Medicine and Cellular Longevity, 2021
NLRP3 inflammasome-mediated pyroptosis is a proinflammatory programmed cell death pathway, which plays a vital role in functional outcomes after stroke.
Yuanyuan Ran   +9 more
semanticscholar   +1 more source

Purification of Curcumin from Ternary Extract-Similar Mixtures of Curcuminoids in a Single Crystallization Step

open access: yes, 2020
Crystallization-based separation of curcumin from ternary mixtures of curcuminoids having compositions comparable to commercial extracts was studied experimentally.
Horosanskaia, E.   +3 more
core   +1 more source

Curcumin Mitigates Immune-Induced Epithelial Barrier Dysfunction by Campylobacter jejuni [PDF]

open access: yes, 2019
Campylobacter jejuni (C. jejuni) is the most common cause of foodborne gastroenteritis worldwide. The bacteria induce diarrhea and inflammation by invading the intestinal epithelium. Curcumin is a natural polyphenol from turmeric rhizome of Curcuma longa,
Bereswill, Stefan   +14 more
core   +1 more source

Biomedical Applications and Bioavailability of Curcumin—An Updated Overview

open access: yesPharmaceutics, 2021
Curcumin, a yellow-colored molecule derived from the rhizome of Curcuma longa, has been identified as the bioactive compound responsible for numerous pharmacological activities of turmeric, including anticancer, antimicrobial, anti-inflammatory ...
S. Sohn   +8 more
semanticscholar   +1 more source

Synthesis and Evaluation of the Anti-Oxidant Capacity of Curcumin Glucuronides, the Major Curcumin Metabolites

open access: yesAntioxidants, 2015
Curcumin metabolites namely curcumin monoglucuronide and curcumin diglucuronide were synthesized using an alternative synthetic approach. The anti-oxidant potential of these curcumin glucuronides was compared with that of curcumin using DPPH scavenging ...
Ambar K. Choudhury   +4 more
doaj   +1 more source

The anti-adhesive effect of curcumin on Candida albicans biofilms on denture materials [PDF]

open access: yes, 2017
The use of natural compounds as an alternative source of antimicrobials has become a necessity given the growing concern over global antimicrobial resistance. Polyphenols, found in various edible plants, offers one potential solution to this. We aimed to
Alalwan, Hasanain   +8 more
core   +1 more source

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