Production of Curcuminoids in Engineered Escherichia coli
Journal of Microbiology and Biotechnology, 2017 Curcumin, a hydrophobic polyphenol derived from the rhizome of the herb Curcuma longa, possesses diverse pharmacological properties, including anti-inflammatory, antioxidant, antiproliferative, and antiangiogenic activities. Two curcuminoids (dicinnamoylmethane and bisdemethoxycurcumin) were synthesized from glucose in Escherichia coli.
Eun Ji, Kim +3 more
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Curcumin and curcuminoids in quest for medicinal status.
Acta Biochimica Polonica, 2012 Curcumin, known for thousands of years as an Ayurvedic medicine, and popular as a spice in Asian cuisine, has undergone in recent times remarkable transformation into a drug candidate with prospective multipotent therapeutic applications. Characterized by high chemical reactivity, resulting from an extended conjugated double bond system prone to ...
Grzegorz, Grynkiewicz, Piotr, Ślifirski
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Plant-derived health - the effects of turmeric and curcuminoids [PDF]
, 2009 Plants contain numerous polyphenols, which have been shown to reduce inflammation and hereby to increase resistance to disease. Examples of such polyphenols are isothiocyanates in cabbage and broccoli, epigallocatechin in green tee, capsaicin in chili ...
Bengmark, S, Gil, A, Mesa, MD
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Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway [PDF]
, 2016 Background. Tuberculosis remains a major global health concern. The ability to prevent phagosome-lysosome fusion is a key mechanism by which intracellular mycobacteria, including Mycobacterium tuberculosis, achieve long-term persistence within host cells.
A Morgan +73 more
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The Anti-Inflammatory Role of Mannich Curcuminoids; Special Focus on Colitis
Molecules, 2019 The incidence of inflammatory bowel disease (IBD) increases gradually in Western countries with high need for novel therapeutic interventions. Mannich curcuminoids, C142 or C150 synthetized in our laboratory, have been tested for anti-inflammatory ...
Gábor J. Szebeni +12 more
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Enhancing curcuminoid production using E. coli engineered strains [PDF]
, 2016 Curcuminoids are natural secondary metabolites from the herb Curcuma longa. Their beneficial properties, mainly as anti-cancer agents, have been exhaustively reported but the therapeutic effect of curcumin is limited by its fast systemic elimination ...
Couto, Márcia +2 more
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Anti-invasive effects of curcuminoid compounds from Curcuma aromatica Salisb. on murine colon 26-L5 carcinoma cells [PDF]
, 2002 ショウガ科に属する Curcuma aromatica Salisb. の根茎のクロロホルム抽出エキスから,化学構造の明らかな4種のクルクミンおよびその関連化合物:curcumin(CA-1),demethoxycurcumin(CA-2),5\u27-methoxycurcumin(CA-3),bisdemethoxycurcumin(CA-4)を分離した。これらの化合物を用いてマウス結腸癌細胞(colon 26-L5)に対する増殖,基底膜への浸潤,細胞運動に及ぼす効果について検討した。クルクミン ...
KANOKMEDHAKUL Kwanjai +4 more
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A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin [PDF]
, 2014 CurcumalongaL.(Zingiberaceaefamily)anditspolyphenoliccompoundcurcuminhavebeensubjectedtoavarietyofantimicrobial investigationsduetoextensivetraditionalusesandlowsideeffects.Antimicrobialactivitiesforcurcuminandrhizomeextractof C ...
AbdulKadir, Habsah +5 more
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Curcuminoids as Potent Inhibitors of Lipid Peroxidation
Journal of Pharmacy and Pharmacology, 1994 Abstract Earlier studies showed that curcumin is a potent inhibitor of iron-catalysed lipid peroxidation. Demethoxycurcumin, bisdemethoxycurcumin and acetylcurcumin were tested for their ability to inhibit iron-stimulated lipid peroxidation in rat brain homogenate and rat liver microsomes.
, Sreejayan, M N, Rao
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PENGARUH PEMBERIAN EKSTRAK KUNYIT (Curcuma longa) TERHADAP JUMLAH EOSINOFIL DI JARINGAN PARU PADA PENYAKIT ALERGI : Studi Eksperimental pada Mencit BALB/c yang Diinduksi Ovalbumin [PDF]
, 2016 Background: Turmeric (Curcuma longa) is a spice that is often used as traditional medicine. The active ingredient of turmeric, curcumin, acts as an anti-inflammatory on the allergic reaction.
Ningrum, Tri Setya +2 more
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