The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Breeding Wheat for Durable Leaf Rust Resistance in Southern Africa: Variability, Distribution, Current Control Strategies, Challenges and Future Prospects. [PDF]
Figlan S +5 more
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Design of a Measuring System for Electricity Quality Monitoring within the SMART Street Lighting Test Polygon: Pilot Study on Adaptive Current Control Strategy for Three-Phase Shunt Active Power Filters. [PDF]
Martinek R +8 more
europepmc +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
An AC voltage sensorless predictive current control method for grid-tied inverter with enhanced robustness against current DC offset. [PDF]
Zhang G, Dong W, Meng L, Li J, Wang J.
europepmc +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Current Control of Spin Helicity and Nonreciprocal Charge Transport in a Multiferroic Conductor. [PDF]
Yamaguchi D +3 more
europepmc +1 more source
Non-Periodic Current Regulation in Digitally Controlled Hysteresis Current Controller
This paper investigates the challenges associated with non-periodic current tracking in digitally controlled Hysteresis Current Controllers (HCC) within grid-connected inverter systems. It examines the dynamic response of the controller when the grid phase undergoes variations, leading to deviations in current tracking.
openaire +1 more source

