Results 21 to 30 of about 272,115 (235)
Stereodivergent Synthesis of Three Contiguous Stereogenic Centers by Cu/Ir-Catalyzed Borylallylation. [PDF]
Angew Chem Int Ed EnglAn alkene borylallylation strategy enabled by cooperative Cu/Ir‐catalysis has been uncovered for accessing three contiguous stereogenic centres. This strategy is notable given the inherent challenges of constructing molecules with multiple stereocenters while maintaining high selectivity bearing diverse functional groups.
Das S, Dorn SK, Brown MK.
europepmc +2 more sources
A modular flow reactor for performing Curtius rearrangements as a continuous flow process
Organic and Biomolecular Chemistry, 2008 Marcus Baumann +2 more
exaly +3 more sources
Novel Sulfur-Containing Polyurethanes using 5-(Chloromethyl)Furfural as a Renewable Building Block. [PDF]
ChemSusChemA novel methodology is presented for synthesizing biomass‐derived diols using 5‐(chloromethyl)furfural, thiols, and mild reaction conditions. These innovative diols are subsequently utilized in the production of new polyurethanes via polyaddition with both commercially available and biomass‐derived diisocyanates.
Mora Vargas JA +5 more
europepmc +2 more sources
Deconstructive Radical-Radical Coupling for Programmable Remote Acylation. [PDF]
Angew Chem Int Ed EnglA unified approach to access a variety of 1,n‐dicarbonyls through a radical‐promoted deconstructive process utilizing dual photocatalysis/carbene catalysis is reported. The utility of this strategy is demonstrated with a broad scope with robust functional group tolerance along with application in the preparation of γ‐amino esters, three‐component ...
Cao J, Schull CR, Scheidt KA.
europepmc +3 more sources
Pharmaceuticals, 2023 On the basis of previous reports, novel 2-benzoylhydrazine-1-carboxamides were designed as potential inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Inhibitors of these enzymes have many clinical applications.
Neto-Honorius Houngbedji +6 more
doaj +1 more source
Heliyon, 2023 A novel compound N-benzyl-2-oxo-1,2-dihydrofuro [3,4-d]pyrimidine-3(4H)-carboxamide (DHFP) was synthesized by addition, rearrangement, and intramolecular cyclization reactions.
Ayşen Şuekinci Yılmaz +1 more
doaj +1 more source
Strategy-Level Prodrug Synthesis. [PDF]
ChemistryProdrug approaches can be expanded by increasing options for controlling site‐selective functionalization, boosting the range of linking groups, and enhancing the chemoselectivity of reactive group incorporation. This Concept describes strategy‐level prodrug synthesis, whereby these issues are addressed at an early stage of a sequence.
Geaneotes PJ, Floreancig PE.
europepmc +2 more sources
Total Synthesis of Isodaphlongamine H by Iridium-Catalyzed Reductive [3 + 2] Cycloaddition of N-Hydroxylactam. [PDF]
Angew Chem Int Ed EnglThe total synthesis of isodaphlongamine H was accomplished by a lactam strategy. This strategy started with alkylation and N‐oxidation of a readily available chiral lactam. For the key functionalization of the amide carbonyl, an iridium‐catalyzed reductive [3 + 2] cycloaddition of the N‐hydroxylactam afforded the tricyclic isoxazolidine, which was ...
Iwamoto S +15 more
europepmc +3 more sources