Results 51 to 60 of about 265,896 (190)

[(Cp-R)M(CO)3] (M= Re or 99mTc) Conjugates for Theranostic Receptor Targeting

CHIMIA, 2013
Cyclopentadienyl complexes of 99mTc became accessible via a retro Diels-Alder synthetic approach of dimerized cyclopentadiene derivatives. So far, this approach was limited to derivatives comprising a carboxylic acid group, directly conjugated ...
Daniel Can, Paul Schmutz, Samer Sulieman, Bernhard Spingler, Roger Alberto   +4 more
doaj   +1 more source

Crystal structures of 1′-aminocobaltocenium-1-carboxylic acid chloride monohydrate and of its azo dye 1′-[2-(1-amino-2,6-dimethylphenyl)diazen-1-yl]cobaltocenium-1-carboxylic acid hexafluoridophosphate monohydrate

Acta Crystallographica Section E: Crystallographic Communications, 2019
1′-Aminocobaltocenium-1-carboxylic acid chloride, [Co(C5H6N)(C6H5O2)]Cl·H2O, (3), and its azo derivative 1′-[2-(1-amino-2,6-dimethylphenyl)diazen-1-yl]cobaltocenium-1-carboxylic acid hexafluoridophosphate, [Co(C13H14N3)(C6H5O2)]PF6·H2O (5) were obtained ...
Markus Jochriem, Klaus Wurst, Holger Kopacka, Benno Bildstein   +3 more
doaj   +1 more source

Tandem Continuous Flow Curtius Rearrangement and Subsequent Enzyme-Mediated Impurity Tagging

Organic Process Research & Development, 2020
The use of continuous flow as an enabling technology within the fine chemical and pharmaceutical industries continues to gain momentum.
M. Baumann, Alexander Leslie, T. Moody, Megan Smyth, S. Wharry   +4 more
semanticscholar   +1 more source

Boranes in Organic Chemistry 2. ОІ-Aminoalkyl- and ОІ-Sulfanylalkylboranes in Organic Synthesis

Eurasian Chemico-Technological Journal, 2002
Problems on using of ОІ-aminoalkyl- and ОІ-sulfanylalkylboranes in organic synthesis are considered in this review. The synthesis of boron containing a-aminoacids by Curtius rearrangement draws attention.
V.M. Dembitsky, G.A. Tolstikov, M. Srebnik   +2 more
doaj   +1 more source

2-((Diphenylmethylene)amino)ethyl N-(Cyclohexyl)carbamate

Molbank
Lipid-like nanoparticles (LLNPs) have been shown to be an effective encapsulation and delivery tool for therapeutic molecules. While the preclinical development of lipid nanoparticle formulations has been of paramount importance, next-generation LLNPs ...
Bailey N. Baxter, Mary Helene Marmande, Alyssa M. Albers, Manisha R. Gangasani, Hao N. Le, Omar E. Molokhia, Juanita Monteiro-Pai, Kyndall V. Ransom, David C. Forbes   +8 more
doaj   +1 more source

SmI2‐Catalyzed Coupling of Alkyl Housane Ketones and Alkenes in an Approach to Norbornanes

Angewandte Chemie, Volume 137, Issue 39, September 22, 2025.
Samarium diiodide (Sml2) is an effective catalyst for the mild, atom‐economical coupling of bicyclo[2.1.0]pentane, or housane, ketones, and electron‐deficient alkenes to give functionalized norbornane structural motifs not easily accessible by classical cycloaddition approaches.
Debayan Roy, Jack I. Mansell, Giorgia Barison, Song Yu, Rocco Katavic, Ciro Romano, Nikolas Kaltsoyannis, David J. Procter   +7 more
wiley   +1 more source

Hydrogen Peroxide‐Responsive Aminoferrocene Prodrugs

European Journal of Organic Chemistry, Volume 28, Issue 33, September 20, 2025.
To improve sensitivity toward H2O2, the boronic acid pinacol ester in known aminoferrocene‐based anticancer prodrug 13b is replaced with an α‐ketamide fragment to obtain prodrug 2a and some of its N‐alkylated derivatives. 2a exhibits substantially improved cytotoxicity in vitro toward ovarian cancer A2780 and Burkitt's lymphoma BL‐2 cells.
Marlies Körber, Jennifer Rühle, Fabian Halter, Andriy Mokhir   +3 more
wiley   +1 more source

The Dihydroindeno[2,1‐c]fluorene Core: From Syntheses to Properties and Potential Applications

European Journal of Organic Chemistry, Volume 28, Issue 32, August 28, 2025.
In this review, the latest research progress in synthesis and application of variously decorated aromatic compounds possessing the indeno[2.1‐c]fluorene scaffold is summarized. In addition to covering synthetic endeavors, their transformation to other structurally related aromatic compounds and their physical properties and possible applications are ...
Timothée Cadart, Martin Kotora
wiley   +1 more source

Synthesis of New N,N′‐Diarylureas and Their Theoretical Study as Cannabinoid‐1 Receptor Inhibitors

ChemPlusChem, Volume 90, Issue 8, August 2025.
A series of new pyrazolo‐ and triazolo‐based N,N′‐diarylureas is synthesized following the triphosgene protocol in the last step. Density functional theory calculations and molecular docking provide strong evidence that all new compounds bind strongly to the cannabinoid‐1 (CB‐1) receptor, showing comparable results with the known allosteric CB‐1 ...
Eirini Tsemperlidou, Nikitas Georgiou, Demeter Tzeli, Nikolaos Karousis, George Varvounis   +4 more
wiley   +1 more source

Advances in Mechanochemical C─H Functionalization: A Comparative Study with Solvent‐Based Approaches

ChemCatChem, Volume 17, Issue 13, July 8, 2025.
This review presents the latest advancements made in mechanochemical transition metal catalyzed C─H functionalization, comparing its efficiency, sustainability and scope with traditional solvent‐based methods. By offering a side‐by‐side comparison, it equips organic chemists with the insights needed to select the most effective approach for ...
Nanditha Kattukudiyil Narayanan, Michael Schnürch   +1 more
wiley   +1 more source