Results 51 to 60 of about 272,115 (235)

[(Cp-R)M(CO)3] (M= Re or 99mTc) Conjugates for Theranostic Receptor Targeting

CHIMIA, 2013
Cyclopentadienyl complexes of 99mTc became accessible via a retro Diels-Alder synthetic approach of dimerized cyclopentadiene derivatives. So far, this approach was limited to derivatives comprising a carboxylic acid group, directly conjugated ...
Daniel Can, Paul Schmutz, Samer Sulieman, Bernhard Spingler, Roger Alberto   +4 more
doaj   +1 more source

Computational Study of Ignored Pericyclic Reactions: Rearrangements of 1,2‐Bis(Diazo)Alkanes to 1,2,3,4‐Tetrazines and Subsequent Fragmentations

Angewandte Chemie, Volume 137, Issue 45, November 3, 2025.
DFT calculations of the 8π‐electrocyclization of 1,2‐bis(diazo)alkanes and of other bis‐1,3‐dipoles reveal that this process can establish a so far ignored route to heterocycles such as 1,2,3,4‐tetrazines. Alternative reaction channels via carbenes or nitrenes leading to fragmentation products are discussed.
Hans‐Ulrich Reissig, Ernst‐Ulrich Würthwein   +1 more
wiley   +2 more sources

Synthesis and Quantitative Structure–Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6-Methylguanine-DNA-methyltransferase, DNA Mismatch Repair and p53. [PDF]

, 2013
The antitumor prodrug Temozolomide is compromised by its dependence for activity on DNA mismatch repair (MMR) and the repair of the chemosensitive DNA lesion, O6-methylguanine (O6-MeG), by O6-methylguanine-DNA-methyltransferase (EC 2.1.1.63, MGMT). Tumor
Arris C. E., Arrowsmith J., Barvaux V. A., Boberg F., Boyd M. R., Bunz F., Damera K., Darkes M. J. M., De K., Denny B. J., Dimitrios Pletsas, Dinca E. B., Elrashied A. E. Garelnabi, Garelnabi E. A. E., Hirose Y., Honnalli S. S., Judson P. L., Karran P., Karran P., Kotera M., Leteurtre F., Li Li, Liu L., McElhinney R. S., McGarrity J. F., Mladek A. C., Nishizuka S., Pletsas D., Richard T. Wheelhouse, Roger M. Phillips, Sarkaria J. N., Schmidt B. F., Schmiedekamp A., Shealy Y. F., Siddiqui A. A., Smith R. H., Stevens M. F. G., Svilar D., Wang Y., Wheelhouse R. T., Wheelhouse R. T., Zhang J., Zhang J.   +42 more
core   +1 more source

Synthesis of Ureido-Linked Glycosylated Amino Acids from N α-Fmoc-Asp/Glu-5-oxazolidinones and Their Application to Neoglycopeptide Synthesis [PDF]

, 2008
A simple route for the synthesis of ureido-linked glycosylated amino acids has been described. The key step involves the reaction of isocyanates derived from N α-Fmoc-Asp/Glu-5-oxazolidinones 1 with glycosyl amines followed by hydrolysis.
Sureshbabu, V.V., Venkataramanarao, R.
core   +1 more source

Crystal structures of 1′-aminocobaltocenium-1-carboxylic acid chloride monohydrate and of its azo dye 1′-[2-(1-amino-2,6-dimethylphenyl)diazen-1-yl]cobaltocenium-1-carboxylic acid hexafluoridophosphate monohydrate

Acta Crystallographica Section E: Crystallographic Communications, 2019
1′-Aminocobaltocenium-1-carboxylic acid chloride, [Co(C5H6N)(C6H5O2)]Cl·H2O, (3), and its azo derivative 1′-[2-(1-amino-2,6-dimethylphenyl)diazen-1-yl]cobaltocenium-1-carboxylic acid hexafluoridophosphate, [Co(C13H14N3)(C6H5O2)]PF6·H2O (5) were obtained ...
Markus Jochriem, Klaus Wurst, Holger Kopacka, Benno Bildstein   +3 more
doaj   +1 more source

Marine invertebrate metabolites with anticancer activities: solutions to the "supply problem" [PDF]

, 2016
Marine invertebrates provide a rich source of metabolites with anticancer activities and several marine-derived agents have been approved for the treatment of cancer.
Chandra, S., Dasari, R., Gomes, N.G.M., Kiss, R., Kornienko, A.   +4 more
core   +2 more sources

Boranes in Organic Chemistry 2. ОІ-Aminoalkyl- and ОІ-Sulfanylalkylboranes in Organic Synthesis

Eurasian Chemico-Technological Journal, 2002
Problems on using of ОІ-aminoalkyl- and ОІ-sulfanylalkylboranes in organic synthesis are considered in this review. The synthesis of boron containing a-aminoacids by Curtius rearrangement draws attention.
V.M. Dembitsky, G.A. Tolstikov, M. Srebnik   +2 more
doaj   +1 more source

Synthetic approaches to coronafacic acid, coronamic acid, and coronatine [PDF]

, 2016
The phytotoxin coronatine (COR) is a functional mimic of the active plant hormone (+)-7-iso-jasmonoyl-l-isoleucine (JA-IIe), which regulates stress responses.
Frye, Elizabeth C., Jamieson, Craig, Ling, Kenneth B., Littleson, Mairi M., Russell, Claire J., Watson, Allan J. B.   +5 more
core   +1 more source

Synthesis of peptidyl ureas using p-​nitrophenyl (9-​fluorenylmethoxycarbonylamino)​methylcarbamate derivatives [PDF]

, 2004
Carbamates Fmoc-​NHCHRNHCO2C6H4NO2-​p (Fmoc is 9-​fluorenylmethoxycarbonyl, R is an amino acid side chain) were prepd. using isocyanates derived from Fmoc-​amino acid azides and p-​nitrophenol in the presence of an equimolar quantity of N ...
Babu Vommina V Suresh, ., Patil Basanagoud, S., Vasanthakumar Ganga-Ramu, .   +2 more
core   +1 more source

2-((Diphenylmethylene)amino)ethyl N-(Cyclohexyl)carbamate

Molbank
Lipid-like nanoparticles (LLNPs) have been shown to be an effective encapsulation and delivery tool for therapeutic molecules. While the preclinical development of lipid nanoparticle formulations has been of paramount importance, next-generation LLNPs ...
Bailey N. Baxter, Mary Helene Marmande, Alyssa M. Albers, Manisha R. Gangasani, Hao N. Le, Omar E. Molokhia, Juanita Monteiro-Pai, Kyndall V. Ransom, David C. Forbes   +8 more
doaj   +1 more source