Results 71 to 80 of about 8,110 (222)
N‐ to C‐Peptide Synthesis, Arguably the Future for Sustainable Production
Journal of Peptide Science, Volume 31, Issue 6, June 2025.The advent of epimerization‐free methods for coupling in N‐ to C‐direction synthesis offers improved atom economy for sustainable peptide synthesis. ABSTRACT A revolution in peptide production arrived from the innovation of carboxylate to amine C‐ to N‐direction solid‐phase synthesis.
Kinshuk Ghosh, William D. Lubell
wiley +1 more source
Tamped functions: A rearrangement in dimension 1 [PDF]
arXiv, 2019 We define a new rearrangement, called rearrangement by tamping, for non-negative measurable functions defined on R+. This rearrangement has many properties in common with the well-known Schwarz non-increasing rearrangement such as the P{\'o}lya-Szeg{\"o} inequality.
arxiv
Effective Baselines for Multiple Object Rearrangement Planning in Partially Observable Mapped Environments [PDF]
arXiv, 2023 Many real-world tasks, from house-cleaning to cooking, can be formulated as multi-object rearrangement problems -- where an agent needs to get specific objects into appropriate goal states. For such problems, we focus on the setting that assumes a pre-specified goal state, availability of perfect manipulation and object recognition capabilities, and a ...
arxiv
Chemistry – A European Journal, Volume 31, Issue 27, May 14, 2025.Chemical inhibition of K‐Ras posttranslational prenylation represents a promising strategy against aggressive cancers. A structure‐based design produces piperidine‐based peptidomimetics conjugated to cationic modules, effectively inhibiting FTase and GGTase I at single‐digit nanomolar concentrations.
Naomi Horiuchi +8 more
wiley +1 more source
Rearrangement Events on Circular Genomes [PDF]
arXiv, 2022 Early literature on genome rearrangement modelling views the problem of computing evolutionary distances as an inherently combinatorial one. In particular, attention was given to estimating distances using the minimum number of events required to transform one genome into another.
arxiv
Skeletal Rearrangements of Amides via Breaking Inert Bonds
Chemistry – A European Journal, Volume 31, Issue 25, May 5, 2025.This review highlights advances in amide skeletal rearrangement reactions over the past two decades, categorized by the initial bond cleavages: C─N bond cleavage, C─C bond cleavage, and C═O bond activation. It summarizes emerging strategies, mechanistic insights, and synthetic applications, providing a focused perspective on recent developments in this
Rui Zhang, Guangbin Dong
wiley +1 more source
Research Projects How They Sprout, Bloom, and Wither Away
The Chemical Record, Volume 25, Issue 5, May 2025.What is most exciting in doing research? Not to reach the stated goal, but the unforseen encounters on the way, and to realize their implications! Abstract The conception, initiation, major achievements, and termination of twelve different research projects in our research group are described. Covering a period of four decades, they mirror the changing
Reinhard W. Hoffmann
wiley +1 more source
T3P® (propylphosphonic anhydride) Mediated Conversion of Carboxylic Acids into Acid Azides and one-pot Synthesis of Ureidopeptides [PDF]
, 2010 A general, mild, efficient, and environmentally benign protocol, which makes use of T3P® as an acid activating agent for the direct synthesis of acid azides from carboxylic acids is described.
Basavaprabhu, . +3 more
core +1 more source
A new rearrangement inequality and its application for L^2-constraint minimizing problems [PDF]
arXiv, 2013 We study $L^2$-constraint minimizing problems related to elliptic systems. We introduce a new rearrangement to show $H^1$-precompactness of any minimizing sequences. Some strict inequality for the new rearrangement is obtained. It is a key to exclude the dichotomy of minimizing sequences.
arxiv
Rearrangements and Leibniz-type rules of mean oscillations [PDF]
arXiv, 2017 We shall prove a rearrangement inequality in probability measure spaces in order to obtain sharp Leibniz-type rules of mean oscillations in Lp-spaces and rearrangement invariant Banach function spaces.
arxiv