Results 51 to 60 of about 52,723 (304)
Brittle-fracture simulations of curved cleavage cracks in α-iron: A molecular dynamics study
AIP Advances, 2020 Although body-centered-cubic (bcc) metals and alloys are ubiquitous as structural materials, they are brittle, particularly at low temperatures; however, the mechanism of their brittle fracture is not fully understood.
T. Suzudo, K. Ebihara, T. Tsuru
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Correlation between the pivot node concept and fatigue crack closure [PDF]
, 2018 The study of fatigue crack growth has been commonly done by means of bi-dimensional models and assuming a homogeneous behaviour through the thickness. According to the specimen thickness, a state of plane stress or plane strain is presumed.
Camas, Daniel +2 more
core
Multiple wavemode scanning for near and far-side defect characterisation [PDF]
, 2020 The combination of ultrasonic inspections using different wavemodes can give more information than is available with single mode inspection. In this work, the response of shear and Rayleigh waves to surface-breaking defects propagating on the near-side ...
Edwards, R. S. (Rachel S.), Xiang, L.
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Jixie qiangdu, 2015 In this article,elastic-plastic curved crack tip opening displacement in hardened material under quasi-static loads has been mainly studied,and curved crack tip opening displacement has been calculated as a practical application of a second order ...
YANG DaPeng +4 more
doaj
Propagation Law of Cracks in Surrounding Rock of Different Shape Tunnels Under Adjacent Blasting
Meikuang Anquan, 2020 To understand the effect of the tunnel section shape on the crack propagation law of surrounding rock in adjacent tunnel under blast loading, detailed research is carried out by model test and extended finite element(XFEM).
LIU Kang, GUO Dongming, ZHANG Shuai, SHI Zhenxin, CHEN Jin
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Reviews on Advanced Materials Science, 2023 In the present study, a new type of slightly curved arc HRB400 steel bars (SCAHSs) was proposed to solve the problem of temperature-induced stress loss in mass concrete structures without cutting off steel bars.
Zhuang Mei-Ling +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
3D numerical modelling of twisting cracks under bending and torsion of skew notched beams [PDF]
, 2017 The testing of mode III and mixed mode failure is every so often encountered in the dedicated literature of mechanical characterization of brittle and quasi-brittle materials.
Benedetti, Lorenzo +2 more
core +5 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source