Results 61 to 70 of about 52,723 (304)

The effects of sintering temperature on the mechanical properties and toughening mechanisms of carbon fibre-reinforced HfB2-SiC composites

Materials Research Express, 2021
HfB _2 -SiC composites were fabricated by the introduction of carbon fibres to meet the mechanical requirements, and hot pressing was the sintering route.
Yaxi Chen
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Validation of a wide plate finite element model using digital image correlation [PDF]

, 2011
To investigate the influence of global plastic deformations on girth weld defect tolerance in pipelines, a parametric finite element model has been developed. This paper provides an experimental validation of the model.
De Keyser, Karel, De Waele, Wim, Denys, Rudi, Hertelé, Stijn, Van Acker, Frederik, Verstraete, Matthias   +5 more
core   +1 more source

Adhesive Contact to a Coated Elastic Substrate [PDF]

, 2007
We show how the quasi-analytic method developed to solve linear elastic contacts to coated substrates (Perriot A. and Barthel E. {\em J. Mat. Res.}, {\bf 2004}, {\em 19}, 600) may be extended to adhesive contacts. Substrate inhomogeneity lifts accidental
A Perriot, Barthel E, Derjaguin B, E Barthel, Gladwell G M L, Greenwood J A, Greenwood J A, Huguet A S, Irwin G R, Johnson K L, Johnson K L, Mary P, Maugis D, Maugis D, Maugis D, Mencik J, Sperling G, Sridhar I, Ting T C T   +18 more
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

A peridynamic theory for linear elastic shells

, 2015
A state-based peridynamic formulation for linear elastic shells is presented. The emphasis is on introducing, possibly for the first time, a general surface based peridynamic model to represent the deformation characteristics of structures that have one ...
Chowdhury, Shubhankar Roy, Reddy, J. N., Roy, Debasish, Roy, Pranesh   +3 more
core   +1 more source

Analysis of Stress Intensity Factors for Curved Cracks.

TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1993
In this paper, the hypersingular integral equation method (HIEM) is applied to calculate the stress intensity factors of curved crack problems. The stress fields induced by two kinds of displacement discontinuity are used as fundamental solutions. Then, the problem is formulated as a system of integral equations with the singularity of the form of r-2.
Nao-Aki Noda, Kazuhiro Oda, Kazumitsu Ishii   +2 more
openaire   +2 more sources

NURBS distance fields for extremely curved cracks [PDF]

Computational Mechanics, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Sevilla, Ruben, Barbieri, Ettore
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

INTERACTION OF CURVED CRACK FACES IN BENDING STRIP (BEAM) UNDER INFLUENCE OF TEMPERATURE FIELD

Structural Mechanics of Engineering Constructions and Buildings, 2014
Some problems of temperature field influence on the growth inhibition of curved crack in the strip (beam) when the strip is bent in the plane by given load system (constant bending moments, uniformly distributed pressure and other) is consider.
A B Mustafayev
doaj