Results 71 to 80 of about 2,227,855 (320)

Chronic treatment with corticosterone increases the number of tyrosine hydroxylase-expressing cells within specific nuclei of the brainstem reticular formation

Frontiers in Neuroanatomy, 2022
Cushing's syndrome is due to increased glucocorticoid levels in the body, and it is characterized by several clinical alterations which concern both vegetative and behavioral functions.
Carla Letizia Busceti, Domenico Bucci, Mariarosaria Scioli, Paola Di Pietro, Ferdinando Nicoletti, Ferdinando Nicoletti, Stefano Puglisi-Allegra, Michela Ferrucci, Francesco Fornai, Francesco Fornai   +9 more
doaj   +1 more source

Forkhead box O3 plays a role in skeletal muscle atrophy through expression of E3 ubiquitin ligases MuRF-1 and atrogin-1 in Cushing's syndrome.

American Journal of Physiology. Endocrinology and Metabolism, 2017
Cushing's syndrome is caused by overproduction of the adrenocorticotropic hormone (ACTH), which stimulates the adrenal grand to make cortisol. Skeletal muscle wasting occurs in pathophysiological response to Cushing's syndrome.
Seol-Hee Kang, Hae-Ahm Lee, Mina Kim, Eunjo Lee, U. Sohn, Inkyeom Kim   +5 more
semanticscholar   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Ectopic ACTH Secretion in a Child With Metastatic Ewing's Sarcoma: A Case Report

Frontiers in Oncology, 2020
Ectopic ACTH syndrome is rare in pediatric age. Sarcomas that cause Ectopic ACTH Syndrome (EAS) are even more uncommon. Currently, only three cases of EAS caused by Ewing' sarcoma have been reported.
Valentina Di Ruscio, Valentina Di Ruscio, Giada Del Baldo, Maria Debora De Pasquale, Rita De Vito, Evelina Miele, Giovanna Stefania Colafati, Annalisa Deodati, Maria Antonietta De Ioris, Assunta Tornesello, Giuseppe Maria Milano, Angela Mastronuzzi   +11 more
doaj   +1 more source

Management of post‐implant fibrous dysplasia in the maxilla: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Fibrous dysplasia is generally rare, and even rarer in older adults. Special care is needed when altering the alveolar bone in these cases, especially if an implant is involved. This case study highlights such a scenario. Methods This case study details the experience of a 63‐year‐old African American female who presented with a ...
Yousef Taha Y. Amrou, Anass M. Koleilat, Abdusalam E. Alrmali, Felipe Nor, Hom‐Lay Wang   +4 more
wiley   +1 more source

Exogenous Cushing's syndrome secondary to intermittent high dose oral prednisone for presumed asthma exacerbations in the setting of multiple emergency department visits

Journal of Clinical and Translational Endocrinology Case Reports, 2017
Glucocorticoid therapies are extensively used in a wide range of medical conditions including respiratory, allergic, inflammatory and autoimmune diseases.
Sanjay Manubolu, MD, MPH, Oguchi Nwosu, MD, FAAFP   +1 more
doaj  

Metabolic profile differences in ACTH‐dependent and ACTH‐independent Cushing syndrome

Chronic Diseases and Translational Medicine, 2022
Background The most common etiologies of Cushing's syndrome (CS) are adrenocorticotropic hormone (ACTH)‐producing pituitary adenoma (pitCS) and primary adrenal gland disease (adrCS), both of which burden patients with metabolic disturbance.
Zhengyang Li, Chen Zhang, Chong Geng, Yongfeng Song   +3 more
doaj   +1 more source

Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement.

Journal of Clinical Endocrinology and Metabolism, 2008
OBJECTIVE Our objective was to evaluate the published literature and reach a consensus on the treatment of patients with ACTH-dependent Cushing's syndrome, because there is no recent consensus on the management of this rare disorder.
B. Biller, A. Grossman, P. Stewart, S. Melmed, X. Bertagna, J. Bertherat, M. Buchfelder, A. Colao, A. Hermus, L. Hofland, A. Klibanski, A. Lacroix, J. Lindsay, J. Newell-Price, L. Nieman, S. Petersenn, N. Sonino, G. Stalla, B. Swearingen, M. Vance, J. Wass, M. Boscaro   +21 more
semanticscholar   +1 more source

Trilostane in dogs [PDF]

, 2010
Over the last 10 years, trilostane, a competitive inhibitor of steroid synthesis, is being widely used for the treatment of canine hyperadrenocorticism.
Alenza, Angles, Baker, Barker, Bell, Benchekroun, Biller, Boag, Braddock, Cerundolo, Chapman, Clemente, Dewis, Dunn, Eastwood, Feldman, Galac, Galac, Golden, Goy-Thollot, Guptill, Hurley, Ian K. Ramsey, Kenefick, Kintzer, Komanicky, Leone, Lorenz, Machida, Mantis, McGee, McGowan, McGrotty, Neiger, Neiger, Neuman, Peterson, Potts, Puddefoot, Ramsey, Ramsey, Randolph, Reusch, Robinson, Ruckstuhl, Semple, Semple, Sieber-Ruckstuhl, Sieber-Ruckstuhl, Skelly, Tebb, Teshima, Tueni, Vaughan, Wenger, Wilbur, Williams, Winterberg, Witt, Zeugswetter   +59 more
core   +1 more source

The potential role of environmentally associated DNA methylation in childhood acute lymphoblastic leukaemia subtypes

International Journal of Cancer, EarlyView.
What's New? The rarity of acute lymphoblastic leukaemia and lack of available environmental data have made the role of environmental factors in genetic subtypes challenging to investigate. Here, the authors performed a CpG‐level analysis to investigate DNA methylation as an intermediate mechanism between environmental risk exposures and acute ...
Jessica R. Saville, Lisa J. Russell, Kay Padget, Akram Ghantous, Jessica Nordlund, Jill A. McKay   +5 more
wiley   +1 more source