Results 51 to 60 of about 1,138,303 (262)

The Polymers of Life: Exploring Cellular Function Through Polymer Concepts

open access: yesAdvanced Science, EarlyView.
Biomolecular phase separation reveals that a hidden layer of cellular organization is governed by the principles of polymer science. This review bridges polymer physics and cell biology, offering a primer on fundamental concepts, proposing a framework for interrogating cellular function, and synthesizing biophysical methods for decoding macromolecular ...
Mark Chen, Ashutosh Chilkoti
wiley   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

open access: yesAdvanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo   +11 more
wiley   +1 more source

HUBUNGAN ANTARA CUSTOMER VALUE DENGAN INTENSI PEMBELIAN BATIK SEMARANGAN PADA ANGGOTA DHARMA WANITA PERSATUAN UNIVERSITAS DIPONEGORO

open access: yesJurnal Empati, 2020
Penelitian ini bertujuan untuk mengetahui hubungan antara customer value dengan intensi pembelian Batik Semarangan pada anggota Dharma Wanita Persatuan Universitas Diponegoro.
Hana Nugraheni Nusawie, Diana Rusmawati
doaj   +1 more source

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

open access: yesAdvanced Science, EarlyView.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan   +7 more
wiley   +1 more source

ANALISIS CUSTOMER CONTACT DAN SERVICE GUARANTEE TERHADAP CUSTOMER SATISFACTION DENGAN CUSTOMER VALUE SEBAGAI VARIABEL INTERVENING

open access: yesJurnal Studi Manajemen Organisasi, 2015
The background of this research is the reduction of direct interaction and a guarantee that the company gave notice to the customer. This study aims to determine how much influence customer contact and service guarantee to customer satisfaction with ...
Fahmi Haikal Maladzi, Rizal Hari Magnadi
doaj   +1 more source

How to Improve Value Creation by Service Interaction: The Role of Customer–Environment Fit and Efficacy

open access: yesFrontiers in Psychology, 2020
Under the service-dominant logic, the interactions between employee and customer create opportunities for value creation. Yet, prior research has ignored the underlying mechanism by which service interaction might improve customer value creation.
Liang Hong, Hongyan Yu, Tingyi Wang
doaj   +1 more source

Analyzing Product Efficiency – A Customer-Oriented Approach [PDF]

open access: yes
The purpose of this study is to provide a broader, economic perspective on customer value management. By developing an efficiency-based concept of customer value we aim at contributing to the presently underrepresented research field of marketing ...
Hans H. Bauer   +2 more
core   +3 more sources

Business Model Innovation [PDF]

open access: yes, 2012
[Excerpt] Who is your customer? What does the customer value? How do you deliver value to customers at an appropriate cost? Business models that focus on the who, what, and how to clarify managerial choices and their consequences underpin the operations ...
Serrat, Olivier
core   +1 more source

Self-selection and risk sharing in a modern world of life-long annuities [PDF]

open access: yes, 2018
Communicating a pension product well is as important as optimising the financial value. In a recent study, we showed that up to 80% of the value of a pension lump sum could be lost if customer communication failed.
Gerrard, R. J. G.   +3 more
core   +1 more source

Safety of Sodium‐Ion Batteries: Evaluation and Perspective from Component Materials to Cells, Modules, and Packs

open access: yesAdvanced Energy Materials, EarlyView.
This review provides a bottom‐up evaluation of sodium‐ion battery safety, linking material degradation mechanisms, cell engineering parameters, and module/pack assembly. It emphasizes that understanding intrinsic material stability and establishing coordinated engineering control across hierarchical levels are vital for preventing degradation coupling ...
Won‐Gwang Lim   +5 more
wiley   +1 more source

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