Results 61 to 70 of about 316,034 (278)

Human Skin/SCID Mouse Chimeras as an In Vivo Model for Human Cutaneous Mast Cell Hyperplasia [PDF]

open access: yes, 1997
Human skin xenografted to mice with severe combined immunodeficiency syndrome (SCID) was evaluated to determine the integrity and fate of human dermal mast cells.
Melpo Christofidou-Solomidou   +42 more
core   +1 more source

Cutaneous types of mastocytosis in paediatry. Case report of maculopapular cutaneous mastocytosis in an infant

open access: yesКлинический разбор в общей медицине, 2020
Mastocytosis is a heterogeneous group of neoplasms characterized by increased mast cells proliferation and accumulation in various organs and tissues. The paper introduces the newest mastocytosis classification and diagnosis principles.
Olga B. Tamrazova, Evgeniya A. Glukhova
doaj   +1 more source

PD-1 Regulates the Growth of Human Mastocytosis Cells

open access: yesAllergology International, 2013
Background: Programmed death-1 (PD-1) is a marker for human neoplastic T cells. Here, we evaluated whether or not PD-1 was also a marker for human mastocytosis, and explored the role of PD-1 in human mastocytosis cells.
Tatsuki R. Kataoka   +9 more
doaj   +1 more source

Mastocytosis: a mutated KIT receptor induced myeloproliferative disorder [PDF]

open access: yes, 2015
Although more than 90% systemic mastocytosis (SM) patients express gain of function mutations in the KIT receptor, recent next generation sequencing has revealed the presence of several additional genetic and epigenetic mutations in a subset of these ...
Chatterjee, Anindya   +2 more
core   +2 more sources

Pseudoxanthomatous mastocytosis in a 2-month female infant

open access: yesIndian Journal of Dermatology, 2022
Mastocytosis is a rare disease characterized by infiltration of mast cells in various tissues like skin, bone marrow, liver, spleen, and gastrointestinal tract. Here, we present a case report of diffuse cutaneous mastocytosis (pseudoxanthomatous type) in
Tulika Rai   +3 more
doaj   +1 more source

Regulation of mast cell function and survival in health and disease [PDF]

open access: yes, 2016
Mast cells are sentinels of danger but they are also the major effector cells in allergic disease causing the well-known allergic symptoms caused by their mediators such as histamine and prostaglandin D2 that are released upon activation. Mastocytosis is
Lyberg, Katarina
core   +1 more source

Generalized Equine Cutaneous Mastocytosis [PDF]

open access: yesVeterinary Pathology, 1972
A newborn foal developed generalized cutaneous mastocytosis characterized by multiple elevated nodules of mast cells in skin and basophil hyperplasia in bone marrow. Skin lesions began as small aggregates of mast cells that progressively enlarged, ulcerated, and regressed spontaneously.
N F, Cheville   +3 more
openaire   +2 more sources

Value of urinary N-methylhistamine measurements m childhood mastocytosis [PDF]

open access: yes, 1996
Background: Histamine is an indicator of mast cell activation. N- methylhistamine (NMH) is a metabolite of histamine that can be measured in urine. Objective: Our purpose was to assess the usefulness of determining urinary NMH levels for the diagnosis ...
De Lijster De Raadt, J. (Jacqueline)   +5 more
core   +1 more source

PAEDIATRIC CUTANEOUS MASTOCYTOSIS : REPORT OF 3 CASES

open access: yesInternational Journal of Clinical Images and Medical Reviews, 2022
Mastocytosis occurs due to clonal, neoplastic proliferation of mast cells that accumulate in one or more organ systems. It is characterized by an abnormal mast cell infiltrates1 . It can be divided into cutaneous and systemic Mastocytosis.
A. Thomas
semanticscholar   +1 more source

An Inflammation-Centric View of Neurological Disease: Beyond the Neuron [PDF]

open access: yes, 2018
Inflammation is a complex biological response fundamental to how the body deals with injury and infection to eliminate the initial cause of cell injury and effect repair.
Facci, Laura   +3 more
core   +2 more sources

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