Results 51 to 60 of about 12,150 (217)
Tryptase in children in the practice of an allergist
The normal serum tryptase level is 0–11.4 ng/ml. Hypertryptasemia occurs with anaphylaxis, systemic mastocytosis, and cutaneous mastocytosis in children. Recently, mast cell activation syndromes are increasingly being diagnosed. The article discusses the
D. Sh. Macharadze
doaj +1 more source
Cutaneous mastocytosis: Two pediatric cases treated with topical pimecrolimus. [PDF]
Cutaneous mastocytosis is characterized by increased numbers of skin mast cells that release mediators causing pruritus, urticaria, and flushing. Most pediatric mastocytosis patients exhibit the pattern of urticaria pigmentosa, which typically appears ...
Azevedo, R +4 more
core +1 more source
Summary Background and Objectives Skin diseases can greatly impair quality of life (QoL) of pediatric patients and their families. The Infants and Toddlers Dermatology Quality of Life questionnaire (InToDermQoL) is the first skin‐generic instrument assessing QoL in children ≤ 4 years, as reported by their caregiver. This study aimed to psychometrically
Juliane Traxler +8 more
wiley +1 more source
Diagnosing Systemic Mastocytosis: State of the Art
ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley +1 more source
European S2k guidelines on management of autoimmune blistering diseases in children and adolescents
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda +31 more
wiley +1 more source
Adult onset of xanthelasmoid mastocytosis: Report of a rare entity
Xanthelasmoid or pseudoxanthomatous mastocytosis is an extremely rare variant of diffuse cutaneous mastocytosis. Herein, we describe an adult male with cutaneous mastocytosis showing multiple widespread yellowish ovoid papules like eruptive xanthoma.
Nafiseh Sadat Nabavi +4 more
doaj +1 more source
Mastocytosis: Fertility and Pregnancy Management in a Rare Disease
Mastocytosis encompasses a subset of rare diseases, characterized by the presence and accumulation of abnormal neoplastic MC in various organ systems, including skin, bone marrow, spleen and gastrointestinal tract.
Jacqueline Ferrari +5 more
doaj +1 more source
Allergen-specific immunotherapy of Hymenoptera venom allergy:also a matter of diagnosis [PDF]
Stings of hymenoptera can induce IgE-mediated hypersensitivity reactions in venom-allergic patients, ranging from local up to severe systemic reactions and even fatal anaphylaxis.
Schiener, Maximilian +4 more
core +2 more sources
ABSTRACT Canine cutaneous mast cell tumour (MCT) is the most common skin neoplasm in dogs, with histopathology serving as both the diagnostic and primary prognostic tool. However, identifying reliable biomarkers is essential for improving clinical decision‐making.
Fernanda Ramalho Ramos +6 more
wiley +1 more source
Mastocytosis is a condition characterized by the disorderly infiltration of mast cells in several tissues and comprises many different clinical situations varying from indolent cutaneous forms to malignant and systemic conditions. Bullous mastocytosis is
Nayak Surajit +3 more
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