Results 71 to 80 of about 12,150 (217)

Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions

MedComm, Volume 7, Issue 3, March 2026.
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu, Rou Xue, Xiangwen Luo, Jiangnan Liao, Zongbo Zhang, Jinhai Deng, Teng Liu, Xin Li, Zhe‐Sheng Chen, Mingzhu Yin   +9 more
wiley   +1 more source

Solitary mastocytoma presenting in an adult: report and literature review of adult-onset solitary cutaneous mastocytoma with recommendations for evaluation and treatment

Dermatology Practical & Conceptual, 2016
Background: Mastocytosis is either cutaneous (with skin-limited proliferation of mast cells) or systemic (with mast cells in extracutaneous sites). The onset of solitary mastocytoma in an adult is rare.
Philip R. Cohen
doaj   +1 more source

Safety Practices During Hymenoptera Venom Immunotherapy: Single‐Centre Experience With Protocolised Intravenous Cannulation and Adrenaline Usage

Allergy, EarlyView.
Callum McWaters, Nicole Weibel, Elizabeth Leahy, Samantha Chan, Kymble Spriggs   +4 more
wiley   +1 more source

French guidelines for the management of nonadvanced mastocytosis in adults

Orphanet Journal of Rare Diseases
Mastocytosis is a rare disease caused by abnormal mast cell accumulation/proliferation in various organs/tissues. Its clinical features exhibit significant variability irrespective of its clinical presentation, classification, global survival or impact ...
Cristina Bulai Livideanu, Stéphane Barete, Ghandi Damaj, Michel Arock, Julien Rossignol, Olivier Hermine   +5 more
doaj   +1 more source

CD117 immunoexpression in canine mast cell tumours: correlations with pathological variables and proliferation markers [PDF]

, 2007
Background Cutaneous mast cell tumours are one of the most common neoplasms in dogs and show a highly variable biologic behaviour. Several prognosis tools have been proposed for canine mast cell tumours, including histological grading and cell ...
Pires Maria A, Lopes Célia, Rema Alexandra, Matos Eduarda, Gil da Costa Rui M, Gärtner Fátima   +5 more
core   +2 more sources

CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas

American Journal of Hematology, Volume 101, Issue 1, Page 110-128, January 2026.
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley   +1 more source

Practical implications of the World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology: Categories and ancillary testing for subtyping of hematolymphoid tumors on FNA biopsy cytopathology using a pattern‐based approach

Cancer Cytopathology, Volume 134, Issue 1, January 2026.
Abstract The objective of the recently published World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology (WHO system) is to standardize the diagnostic approach to fine‐needle aspiration biopsies of hematolymphoid tissues.
Mats Ehinger, Maria Calaminici, Immacolata Cozzolino, Pio Zeppa, Andrew S. Field   +4 more
wiley   +1 more source

Childhood Pseudoxanthomatousmastocytosis; Report of two cases

Indian Journal of Dermatopathology and Diagnostic Dermatology, 2018
Cutaneous mastocytosis (CM) is a mast cell proliferative disorder that commonly affects pediatric population. It has various clinical forms such as urticaria pigmentosa, solitary mastocytoma, telangiectasia macularis eruptiva perstans, diffuse CM, and ...
Bhabani S. T. P. Singh, Tapaswini Tripathy, Bikash Ranjan Kar, Surabhi Singh   +3 more
doaj   +1 more source

Loss of Function of TET2 Cooperates with Constitutively Active KIT in Murine and Human Models of Mastocytosis [PDF]

, 2014
Systemic Mastocytosis (SM) is a clonal disease characterized by abnormal accumulation of mast cells in multiple organs. Clinical presentations of the disease vary widely from indolent to aggressive forms, and to the exceedingly rare mast cell leukemia ...
A Gerbaulet, A Pardanani, A Tefferi, A Tefferi, AC Garcia-Montero, Alexander Gerbaulet, Ann Mullally, AS Yavuz, Axel Roers, Benjamin L. Ebert, BJ Longley, C Akin, C Masserot, C Quivoron, CC Chen, David A. Williams, E Razin, E Soucie, F Delhommeau, F Traina, H Kitayama, H Nagata, Halvard Boenig, HC Tsai, HM Lewis, HP Horny, HP Horny, J Scholten, Jenna Wood, JH Butterfield, JM Klco, JN Ihle, K Moran-Crusio, KJ Aichberger, Mathilde Gavillet, ME Figueroa, Michael Garcia, MM Schittenhelm, NP Shah, P Valent, R Kuhn, Rebekka K. Schneider, Ross L. Levine, S Ito, S Verstovsek, Serena De Vita, SM Langemeijer, SM Langemeijer, TM Wilson, V Ghanim, WD Travis, Y Arinobu, Y Ma, YF He, Z Li, Z Xiang   +55 more
core   +3 more sources

Clinical Scoring of Cutaneous Mastocytosis

Acta Dermato-Venereologica, 2001
There are still many controversies in defining and evaluating mastocytosis. One of the aspects that is missing is a system for clinical evaluation of mastocytosis of the skin. A calculation based on a semi-quantitative analysis of three aspects of mastocytosis was designed. The method is called the scoring index of mastocytosis (SCORMA).
Heide, R., Middelkamp Hup, M. A., Mulder, P. G., Oranje, A. P.   +3 more
openaire   +3 more sources