Results 61 to 70 of about 175,363 (195)

Pathomorphology of cutaneous mastocytosis

open access: yesMeditsinskiy sovet = Medical Council, 2023
Introduction. Mastocytosis as a result of mast cell infiltration of the skin and other organs develops at any age. The relevance of this work is determined by the lack of systematic data on the pathomorphological features of the clinical forms and types of cutaneous mastocytosis, defined by the Consensus European-American Mastocytosis Group and the WHO
E. I. Kasikhina   +5 more
openaire   +1 more source

Clinical features and course of cutaneous mastocytosis in 133 children

open access: yes, 2016
The article reports on a clinical study on 133 children with cutaneous mastocytosis describing the clinical evolution over 10 years of follow up. The type of cutaneous mastocytosis, the clinical features, and the factors predicting long-term outcome are ...
SCHENA, DONATELLA   +3 more
core   +1 more source

An Adult Patient with Systemic Mastocytosis and B-Acute Lymphoblastic Leukemia

open access: yesCase Reports in Medicine, 2014
Mastocytosis is a myeloproliferative neoplasm characterized by clonal expansion of abnormal mast cells, ranging from the cutaneous forms of the disease to mast cell leukemia.
Theodoros Iliakis   +13 more
doaj   +1 more source

Adult onset of xanthelasmoid mastocytosis: Report of a rare entity

open access: yesIndian Journal of Dermatology, 2016
Xanthelasmoid or pseudoxanthomatous mastocytosis is an extremely rare variant of diffuse cutaneous mastocytosis. Herein, we describe an adult male with cutaneous mastocytosis showing multiple widespread yellowish ovoid papules like eruptive xanthoma.
Nafiseh Sadat Nabavi   +4 more
doaj   +1 more source

Beyond Histamine: Mast Cell‐Neuron Communication in Chronic Pruritic and Pain Disorders

open access: yesExperimental Dermatology, Volume 35, Issue 8, August 2026.
ABSTRACT Chronic pruritic and cutaneous pain disorders are increasingly recognized as neuroimmune conditions driven by dynamic interactions between immune and sensory systems. While histamine has historically dominated models of mast cell‐mediated itch, accumulating evidence indicates that non‐histaminergic pathways are central to chronic disease.
Tomer Kagan, Gil Yosipovitch
wiley   +1 more source

Mastocytosis: One Word for Different Diseases

open access: yesOncology and Therapy, 2018
Mastocytosis is a neoplastic disease originating from tissue infiltration by transformed mast cells. The diagnosis requires a high grade of suspicion due to the large variety of presenting symptoms. The World Health Organization classification recognizes
Marianna Criscuolo   +3 more
doaj   +1 more source

Hidden in Plain Sight: Systemic Mastocytosis Manifesting as Isolated Hepatosplenomegaly in the Absence of Cutaneous and Classical Manifestations—A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Systemic mastocytosis (SM) is a rare clonal myeloproliferative neoplasm typically characterized by cutaneous lesions and mediator‐release symptoms. Presentations dominated by visceral organ involvement without skin findings are uncommon and pose a significant diagnostic challenge, often mimicking hematologic malignancies.
Muhammad Sadam Zeb   +9 more
wiley   +1 more source

Current approach to cutaneous mastocytosis in childhood

open access: yes, 2016
Mastocytosis is a heterogeneous disorder characterized by clonal proliferation and accumulation of mast cells in one of more organs which may lead to different clinical pictures.
Deniz Ozceker   +3 more
core   +1 more source

Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab

open access: yesCase Reports in Medicine, 2015
The pathogenesis of mastocytosis is not well defined and thus treatment remains challenging and remains on a palliative basis. We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti ...
Sofie Lieberoth, Simon Francis Thomsen
doaj   +1 more source

Smoldering Systemic Mastocytosis Without Detectable KIT Mutation: A Debilitating Course and Therapeutic Challenge

open access: yesCancer Nexus, Volume 2, Issue 3, July 2026.
Graphical abstract illustrating the clinical course and treatment response. ABSTRACT Systemic mastocytosis (SM) is a clonal hematologic neoplasm driven by activating KIT mutations, particularly D816V. Indolent SM typically follows a stable course, progression to higher‐burden subtypes is uncommon.
Homeniuk Anna   +5 more
wiley   +1 more source

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