Localized Pseudoxanthomatous Mastocytosis of Vulva
Cutaneous mastocytosis (CM) is a mast cell proliferative disorder that is common in the pediatric age group. Common entities are urticaria pigmentosa, solitary mastocytoma, telangiectasia macularis eruptive perstans. and diffuse CM.
Shivi Nijhawan +2 more
doaj +1 more source
Clinical, epidemiological and laboratory features of insect allergy in cutaneous mastocytosis
Introduction. Mastocytosis is a rare neoplasm characterized by abnormal proliferation and activation of clonal mast cells usually harbouring the KIT D816V mutation.
E. Kasikhina, M. Ostretsova, A. Y. Nada
semanticscholar +1 more source
Summary Background and Objectives Skin diseases can greatly impair quality of life (QoL) of pediatric patients and their families. The Infants and Toddlers Dermatology Quality of Life questionnaire (InToDermQoL) is the first skin‐generic instrument assessing QoL in children ≤ 4 years, as reported by their caregiver. This study aimed to psychometrically
Juliane Traxler +8 more
wiley +1 more source
Diagnosing Systemic Mastocytosis: State of the Art
ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley +1 more source
Routine abdominal ultrasonography has limited value in the care for patients with indolent systemic mastocytosis [PDF]
Objectives: Systemic mastocytosis (SM) is a myeloproliferative disease characterized by the accumulation of aberrant mast cells. Since advanced subtypes of SM can lead to organ dysfunction and shortened survival, timely recognition of progressive disease
Daele, P.L.A. (Paul) van +4 more
core +2 more sources
Unsatisfactory agreement using current classification of maculopapular cutaneous mastocytosis
Mastocytosis is a disease characterized by abnormal accumulation and expansion of tissue mast cells in the skin, bone marrow or other organs. Cutaneous (CM) and systemic forms (SM) of mastocytosis have been distinguished.
K. Brockow
semanticscholar +1 more source
Omalizumab for Pediatric Cutaneous Mastocytosis: Case Report and Review
ABSTRACT We report an 11‐month‐old boy with diffuse cutaneous mastocytosis whose severe pruritus and steroid dependence resolved following off‐label treatment with omalizumab. A literature review identified five additional pediatric cases in which omalizumab led to complete symptom resolution in an average of 2 months and permitted discontinuation of ...
Janis Chang +3 more
wiley +1 more source
Tryptase in children in the practice of an allergist
The normal serum tryptase level is 0–11.4 ng/ml. Hypertryptasemia occurs with anaphylaxis, systemic mastocytosis, and cutaneous mastocytosis in children. Recently, mast cell activation syndromes are increasingly being diagnosed. The article discusses the
D. Sh. Macharadze
doaj +1 more source
Experimental and clinical study of the efficacy of medicines containing omega-3 and 6 polyunsaturated fatty acids, in the treatment of inflammatory skin diseases [PDF]
Over the recent years, the attention of scientists regarding the search for alternative means of treatment, including local therapy, of inflammatory skin diseases, has been focused in recent years on medicines containing omega-3 and 6 polyunsaturated ...
Grebennikova, S. V., Maklyakov, Y. S.
core +3 more sources
CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley +1 more source

