Results 11 to 20 of about 5,467 (160)

Failure of B Cell Tolerance in CVID [PDF]

Frontiers in Immunology, 2019
Common variable immunodeficiency (CVID) comprises a group of related disorders defined by defects in B cell function and antibody production. Concurrent autoimmune features are common, but the underlying pathogenic mechanisms of autoimmunity in CVID are ...
Christopher T. Richardson, Christopher T. Richardson, Maria A. Slack, Maria A. Slack, Gitika Dhillon, Carolina Z. Marcus, Jennifer Barnard, Arumugam Palanichamy, Ignacio Sanz, Richard John Looney, Jennifer H. Anolik   +10 more
doaj   +3 more sources

T-cell and monocyte DNA methylation and Wnt dysregulation in common variable immunodeficiency: an exploratory study [PDF]

Frontiers in Immunology
BackgroundMany patients with common variable immunodeficiency (CVID) develop inflammatory/autoimmune complications associated with T-cell and monocyte dysregulation which may involve epigenetic modifications.ObjectiveTo characterize genome-wide CpG ...
Vegard Myhre, Vegard Myhre, Mingyi Yang, Mingyi Yang, Mari Kaarbø, Mai Sasaki Aanensen Fraz, Mai Sasaki Aanensen Fraz, Mai Sasaki Aanensen Fraz, Annika E. Michelsen, Annika E. Michelsen, Børre Fevang, Børre Fevang, Pål Aukrust, Pål Aukrust, Pål Aukrust, Thor Ueland, Thor Ueland, Thor Ueland, Magnar Bjørås, Magnar Bjørås, Magnar Bjørås, Silje Fjellgård Jørgensen, Silje Fjellgård Jørgensen   +22 more
doaj   +2 more sources

CVID Associated with Systemic Amyloidosis [PDF]

Case Reports in Immunology, 2015
Common variable immunodeficiency (CVID) is a frequent primary immune deficiency (PID), which consists of a heterogeneous group of disorders and can present with recurrent infections, chronic diarrhea, autoimmunity, chronic pulmonary and gastrointestinal diseases, and malignancy. Secondary amyloidosis is an uncommon complication of CVID.
PEYNİRCİOĞLU, BANU, ÇAĞDAŞ AYVAZ, DENİZ NAZİRE, Esenboga, Saliha, Tezcan, Ilhan, Sanal, Ozden, Ayhan, Arzu Saglam   +5 more
openaire   +5 more sources

Investigating serum free light chains in patients with common variable immunodeficiency disorder in compare with other immunodeficiency diseases [PDF]

Scientific Reports
Serum free light chains (sFLCs) have recently been introduced as a diagnostic biomarker in common variable immunodeficiency (CVID) patients. Most patients with CVID have undetectable or lower levels of sFLCs compared to people with other types of immune ...
Mohammad Hassan Bemanian, Majid Khoshmirsafa, Mina Ahmadi, Mohamad Nabavi, Saba Arshi, Zahra Chavoshzadeh, Sima Shokri, Morteza Fallahpour, Negin Jafariaghdam, Fatemeh Afrashteh, Samane Asefi, Mehrnaz Mesdaghi, Samin Sharafian   +12 more
doaj   +2 more sources

New diagnostic criteria for CVID [PDF]

Expert Review of Clinical Immunology, 2014
RESPONSE TO: Kumar R, Bhatia A. Common variable immunodeficiency in adults: current diagnostic protocol and laboratory measures. Expert Rev. Clin. Immunol. 10(2), 000-000 (2014).
Rohan, Ameratunga, See-Tarn, Woon, David, Gillis, Wikke, Koopmans, Richard, Steele   +4 more
openaire   +2 more sources

Management of liver disease and portal hypertension in common variable immunodeficiency (CVID)Key points

JHEP Reports, 2023
Summary: Patients with common variable immunodeficiency (CVID) frequently develop liver disease and associated complications, which represent an increasingly prevalent unmet medical need.
Lukas S. Baumert, Angela Shih, Raymond T. Chung   +2 more
doaj   +1 more source

Unexpectedly High Prevalence of Common Variable Immunodeficiency in Finland

Frontiers in Immunology, 2017
BackgroundCommon variable immunodeficiency (CVID) is the most common primary immunodeficiency. Prevalence varies greatly between countries and studies.
Jannica S. Selenius, Jannica S. Selenius, Timi Martelius, Sampsa Pikkarainen, Sanna Siitonen, Eero Mattila, Risto Pietikäinen, Pekka Suomalainen, Arja H. Aalto, Arja H. Aalto, Janna Saarela, Elisabet Einarsdottir, Elisabet Einarsdottir, Elisabet Einarsdottir, Asko Järvinen, Martti Färkkilä, Juha Kere, Juha Kere, Juha Kere, Juha Kere, Mikko Seppänen, Mikko Seppänen   +21 more
doaj   +1 more source

Management of a patient with common variable immunodeficiency and hepatopathy

Allergy, Asthma & Clinical Immunology, 2023
Background Common variable Immunodeficiency (CVID) is a primary immunodeficiency disorder and the most common form of severe antibody deficiency. Both children and adults are affected and clinical manifestations vary widely.
Lea Grümme, Hendrik Schulze-Koops
doaj   +1 more source

Impaired Memory B-Cell Response to Influenza Immunization in Patients With Common Variable Immunodeficiency (CVID)

Pathogens and Immunity, 2021
Background: Common variable immunodeficiency (CVID) is a heterogeneous primary immunodeficiency characterized by low serum antibody levels and recurrent infections.
Wei Zhan, Todd Hatchette, Fengyun Yue, Jun Liu, Haihan Song, Hanqi Zhao, Stephen Betschel, Mario Ostrowski   +7 more
doaj   +1 more source

A Computational Pipeline for the Diagnosis of CVID Patients [PDF]

Frontiers in Immunology, 2019
Common variable immunodeficiency (CVID) is one of the most frequently diagnosed primary antibody deficiencies (PADs), a group of disorders characterized by a decrease in one or more immunoglobulin (sub)classes and/or impaired antibody responses caused by inborn defects in B cells in the absence of other major immune defects.
Annelies Emmaneel, Annelies Emmaneel, Delfien J. Bogaert, Delfien J. Bogaert, Sofie Van Gassen, Sofie Van Gassen, Simon J. Tavernier, Simon J. Tavernier, Simon J. Tavernier, Melissa Dullaers, Filomeen Haerynck, Filomeen Haerynck, Yvan Saeys, Yvan Saeys   +13 more
openaire   +4 more sources