Results 21 to 30 of about 5,467 (160)

Recent advances in elucidating the genetics of common variable immunodeficiency

Genes and Diseases, 2020
Common variable immunodeficiency disorders (CVID), a heterogeneous group of inborn errors of immunity, is the most common symptomatic primary immunodeficiency disorder. Patients with CVID have highly variable clinical presentation.
Vaishali Aggarwal, Aaqib Zaffar Banday, Ankur Kumar Jindal, Jhumki Das, Amit Rawat   +4 more
doaj   +1 more source

Common variable immunodeficiency in an 11-year-old girl – a case report

Journal of Pre-Clinical and Clinical Research, 2020
Common variable immunodeficiency (CVID) is one of the most prevalent, heterogenous primary immunodeficiency syndromes in children and adults. Besides impaired immunoglobulin production by B cells, abnormalities in almost all components of the immune ...
Joanna Pawłowska, Olga Panowicz, Joanna Jerzynska   +2 more
doaj   +1 more source

Antibody response following the third and fourth SARS-CoV-2 vaccine dose in individuals with common variable immunodeficiency

Frontiers in Immunology, 2022
BackgroundThe antibody response after vaccination is impaired in common variable immunodeficiency (CVID).ObjectiveWe aimed to study the spike receptor-binding domain IgG antibody (anti-S-RBD) levels during a four-dose SARS-CoV-2 vaccination strategy and ...
Bibi Uhre Nielsen, Camilla Heldbjerg Drabe, Mike Bogetofte Barnkob, Isik Somuncu Johansen, Anne Kirstine Kronborg Hansen, Anna Christine Nilsson, Line Dahlerup Rasmussen, Line Dahlerup Rasmussen   +7 more
doaj   +1 more source

Gut inflammation in CVID: causes and consequences

Expert Review of Clinical Immunology, 2022
There is a wide spectrum of noninfectious gastrointestinal pathology, causing considerable morbidity and mortality in CVID, where both etiology and effective therapy are under debate.This review will focus on the noninfectious inflammation in the GI tract in CVID patients, covering the both the upper and lower GI tract inflammation, including the liver.
I M, Andersen, S F, Jørgensen
openaire   +2 more sources

The Immune Response to SARS-CoV-2 Vaccination: Insights Learned From Adult Patients With Common Variable Immune Deficiency

Frontiers in Immunology, 2022
CVID patients have an increased susceptibility to vaccine-preventable infections. The question on the potential benefits of immunization of CVID patients against SARS-CoV-2 offered the possibility to analyze the defective mechanisms of immune responses ...
Isabella Quinti, Franco Locatelli, Franco Locatelli, Rita Carsetti, Rita Carsetti   +4 more
doaj   +1 more source

Gastric Cancer Is the Leading Cause of Death in Italian Adult Patients With Common Variable Immunodeficiency

Frontiers in Immunology, 2018
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers
Federica Pulvirenti, Antonio Pecoraro, Francesco Cinetto, Cinzia Milito, Michele Valente, Enrico Santangeli, Ludovica Crescenzi, Francesca Rizzo, Stefano Tabolli, Giuseppe Spadaro, Carlo Agostini, Isabella Quinti   +11 more
doaj   +1 more source

Global Distribution of Common Variable Immunodeficiency (CVID) in the Light of the UNDP Human Development Index (HDI): A Preliminary Perspective of a Rare Disease

Journal of Immunology Research, 2020
Common variable immunodeficiency (CVID), although the most common primary immunodeficiency in humans, is a rare disease. We explored the spatial global distribution and country-wise prevalence of CVID, based on published data and those available from ...
Niels Weifenbach, Annalena A. C. Schneckenburger, Stefan Lötters   +2 more
doaj   +1 more source

The Dysfunctional Immune System in Common Variable Immunodeficiency Increases the Susceptibility to Gastric Cancer

Cells, 2020
Gastric carcinoma (GC) represents the most common cause of death in patients with common variable immunodeficiency (CVID). However, a limited number of cases have been characterised so far.
Irene Gullo, Catarina Costa, Susana L. Silva, Cristina Ferreira, Adriana Motta, Sara P. Silva, Rúben Duarte Ferreira, Pedro Rosmaninho, Emília Faria, José Torres da Costa, Rita Câmara, Gilza Gonçalves, João Santos-Antunes, Carla Oliveira, José C. Machado, Fátima Carneiro, Ana E. Sousa   +16 more
doaj   +1 more source

Assessment of the first presentations of common variable immunodeficiency in a large cohort of patients

BMC Immunology, 2023
Background Common Variable Immunodeficiency (CVID) is a primary immunodeficiency syndrome resulting in recurrent infections, autoimmunity, and granulomatous manifestations.
Hossein Esmaeilzadeh, Armita Jokar-Derisi, Amir Hossein Hassani, Reza Yazdani, Samaneh Delavari, Hassan Abolhassani, Negar Mortazavi, Aida Askarisarvestani   +7 more
doaj   +1 more source

Autoimmune Cytopenias in Common Variable Immunodeficiency Are a Diagnostic and Therapeutic Conundrum: An Update

Frontiers in Immunology, 2022
Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency (PID). CVID is a heterogenous condition and clinical manifestations may vary from increased susceptibility to infections to autoimmune manifestations ...
Sanchi Chawla, Prabal Barman, Rahul Tyagi, Ankur Kumar Jindal, Saniya Sharma, Amit Rawat, Surjit Singh   +6 more
doaj   +1 more source