Results 21 to 30 of about 7,578 (214)

Antibody response following the third and fourth SARS-CoV-2 vaccine dose in individuals with common variable immunodeficiency

Frontiers in Immunology, 2022
BackgroundThe antibody response after vaccination is impaired in common variable immunodeficiency (CVID).ObjectiveWe aimed to study the spike receptor-binding domain IgG antibody (anti-S-RBD) levels during a four-dose SARS-CoV-2 vaccination strategy and ...
Bibi Uhre Nielsen, Camilla Heldbjerg Drabe, Mike Bogetofte Barnkob, Isik Somuncu Johansen, Anne Kirstine Kronborg Hansen, Anna Christine Nilsson, Line Dahlerup Rasmussen, Line Dahlerup Rasmussen   +7 more
doaj   +1 more source

Granulomatous Lymphocytic Interstitial Lung Disease (GLILD) in Common Variable Immunodeficiency (CVID)

Journal of the Belgian Society of Radiology, 2022
Teaching Point: Granulomatous lymphocytic interstitial lung disease is a non-infectious complication of common variable immunodeficiency. Computed tomography (CT) has an important diagnostic value by demonstrating pulmonary nodules, ground glass ...
Nico Hustings, Adriana Dubbeldam, Birgit Weynand   +2 more
doaj   +1 more source

New diagnostic criteria for CVID [PDF]

Expert Review of Clinical Immunology, 2014
RESPONSE TO: Kumar R, Bhatia A. Common variable immunodeficiency in adults: current diagnostic protocol and laboratory measures. Expert Rev. Clin. Immunol. 10(2), 000-000 (2014).
Rohan, Ameratunga, See-Tarn, Woon, David, Gillis, Wikke, Koopmans, Richard, Steele   +4 more
openaire   +2 more sources

CVID-associated TACI mutations affect autoreactive B cell selection and activation [PDF]

, 2013
Common variable immune deficiency (CVID) is an assorted group of primary diseases that clinically manifest with antibody deficiency, infection susceptibility, and autoimmunity.
Tuure Kinnunen, Gentile, M, Cantaert, T, Tineke Cantaert, Menard, L, Laurence Menard, Morbach, H, Saadoun, D, Virdee, M, Neil Romberg, Kinnunen, T, Maurizio Gentile, Rachid, R, Martinez-Pomar, N, Geha, R, Henner Morbach, Matamoros, N, Cunningham-Rundles, C, Nicolas Chamberlain, Nuria Matamoros, Andrea Cerutti, Yen Shing Ng, Bodo Grimbacher, Natalia Martinez-Pomar, Meffre, E, Eric Meffre, David Saadoun, Manmeet Virdee, Rima Rachid, Cerutti, A, Raif Geha, Romberg, N, Brimbacher, B, Chamberlain, N, Charlotte Cunningham-Rundles, Ng, YS   +35 more
core   +1 more source

Screening of functional and positional candidate genes in families with common variable immunodeficiency [PDF]

, 2008
Background: Common variable immunodeficiency (CVID) comprises a heterogeneous group of primary antibody deficiencies with complex clinical and immunological phenotypes.
Grimbacher, B, Thiel, J, Jung, J, Webster, A. David B., Webster, D, Schäffer, Alejandro A., Pan Hammarström, Q, Lougaris, V, Hammarström, L, Salzer, U, Hagena, Tina, Grimbacher, B., Jung, Johannes, Woellner, Cristina, MOSCHESE, VIVIANA, Schaffer, AA, Webster, DA, Birmelin, J, Pan-Hammarström, Qiang, Du, Likun, Schäffer, A, Birmelin, Jennifer, Woellner, C, Neumann, C, Salzer, Ulrich, Metin, A, Lougaris, Vassilios, Plebani, Alessandro, Hagena, T, Grimbacher, Bodo, Pan-Hammarstrom, Q, Du, L, Thiel, Jens, Hammarström, Lennart, Moschese, V, Hammarstroo, L, Metin, Ayse, Plebani, A, Neumann, Carla   +38 more
core   +1 more source

Unexpectedly High Prevalence of Common Variable Immunodeficiency in Finland

Frontiers in Immunology, 2017
BackgroundCommon variable immunodeficiency (CVID) is the most common primary immunodeficiency. Prevalence varies greatly between countries and studies.
Jannica S. Selenius, Jannica S. Selenius, Timi Martelius, Sampsa Pikkarainen, Sanna Siitonen, Eero Mattila, Risto Pietikäinen, Pekka Suomalainen, Arja H. Aalto, Arja H. Aalto, Janna Saarela, Elisabet Einarsdottir, Elisabet Einarsdottir, Elisabet Einarsdottir, Asko Järvinen, Martti Färkkilä, Juha Kere, Juha Kere, Juha Kere, Juha Kere, Mikko Seppänen, Mikko Seppänen   +21 more
doaj   +1 more source

Management of liver disease and portal hypertension in common variable immunodeficiency (CVID)Key points

JHEP Reports, 2023
Summary: Patients with common variable immunodeficiency (CVID) frequently develop liver disease and associated complications, which represent an increasingly prevalent unmet medical need.
Lukas S. Baumert, Angela Shih, Raymond T. Chung   +2 more
doaj   +1 more source

iNKT cells are reduced in CVID. [PDF]

, 2013
(A) Representative staining illustrating the gating strategy used. (B) Comparison between the frequency of iNKT cells in healthy control subjects and CVID patients before IVIg (left panel), and in CVID patients before and after IVIg (right panel).
Jorge Kalil (52916), Markus Moll (109640), Cristina M. Kokron (468576), Dominic Paquin-Proulx (468572), Bianca A. N. Santos (468573), Karina I. Carvalho (244966), Ana Karolina Barreto de Oliveira (468575), Johan K. Sandberg (353026), Myrthes Toledo-Barros (468574), Esper G. Kallas (36139)   +9 more
core   +1 more source

Dysregulated PI3K Signaling in B Cells of CVID Patients [PDF]

, 2022
The altered wiring of signaling pathways downstream of antigen receptors of T and B cells contributes to the dysregulation of the adaptive immune system, potentially causing immunodeficiency and autoimmunity.
Wienands, Jürgen; 3Institute of Cellular and Molecular Immunology, University Medical Center Göttingen, Göttingen, Germany; matthias.muenchhalfen@med.uni-goettingen.de (M.M.); jwienan@gwdg.de (J.W.), Warnatz, Klaus, Maccari, Maria Elena, Boerries, Melanie, Andrieux, Geoffroy; 4Institute of Medical Bioinformatics and Systems Medicine, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; geoffroy.andrieux@uniklinik-freiburg.de (G.A.); melanie.boerries@uniklinik-freiburg.de (M.B.), Ehl, Stephan, Grimbacher, Bodo; 6Institute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany; bodo.grimbacher@uniklinik-freiburg.de (B.G.); maria.elena.maccari@uniklinik-freiburg.de (M.E.M.); stephan.ehl@uniklinik-freiburg.de (S.E.), Eibel, Hermann, Ehl, Stephan; 6Institute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany; bodo.grimbacher@uniklinik-freiburg.de (B.G.); maria.elena.maccari@uniklinik-freiburg.de (M.E.M.); stephan.ehl@uniklinik-freiburg.de (S.E.), Andrieux, Geoffroy, Münchhalfen, Matthias; 3Institute of Cellular and Molecular Immunology, University Medical Center Göttingen, Göttingen, Germany; matthias.muenchhalfen@med.uni-goettingen.de (M.M.); jwienan@gwdg.de (J.W.), Jellusova, Julia; 12Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, Germany; julia.jellusova@tum.de, Wienands, Jürgen, Jellusova, Julia, Grimbacher, Bodo, Harder, Ina; 1Department of Rheumatology and Clinical Immunology, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; ina.harder@uniklinik-freiburg.de (I.H.); hermann.eibel@uniklinik-freiburg.de (H.E.), Eibel, Hermann; 1Department of Rheumatology and Clinical Immunology, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; ina.harder@uniklinik-freiburg.de (I.H.); hermann.eibel@uniklinik-freiburg.de (H.E.), Münchhalfen, Matthias, Maccari, Maria Elena; 6Institute for Immunodeficiency, Center for Chronic Immunodeficiency (CCI), Medical Center, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany; bodo.grimbacher@uniklinik-freiburg.de (B.G.); maria.elena.maccari@uniklinik-freiburg.de (M.E.M.); stephan.ehl@uniklinik-freiburg.de (S.E.), Keller, Baerbel; 1Department of Rheumatology and Clinical Immunology, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; ina.harder@uniklinik-freiburg.de (I.H.); hermann.eibel@uniklinik-freiburg.de (H.E.), Keller, Baerbel, Warnatz, Klaus; 1Department of Rheumatology and Clinical Immunology, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; ina.harder@uniklinik-freiburg.de (I.H.); hermann.eibel@uniklinik-freiburg.de (H.E.), Harder, Ina, Boerries, Melanie; 4Institute of Medical Bioinformatics and Systems Medicine, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; geoffroy.andrieux@uniklinik-freiburg.de (G.A.); melanie.boerries@uniklinik-freiburg.de (M.B.)   +23 more
core   +3 more sources

Impaired Memory B-Cell Response to Influenza Immunization in Patients With Common Variable Immunodeficiency (CVID)

Pathogens and Immunity, 2021
Background: Common variable immunodeficiency (CVID) is a heterogeneous primary immunodeficiency characterized by low serum antibody levels and recurrent infections.
Wei Zhan, Todd Hatchette, Fengyun Yue, Jun Liu, Haihan Song, Hanqi Zhao, Stephen Betschel, Mario Ostrowski   +7 more
doaj   +1 more source