Results 31 to 40 of about 5,467 (160)

602 Cvid

World Allergy Organization Journal, 2012
BACKGROUND: Among the more than 150 different forms of Primary Immunodeficiency Diseases (PID) the CVID is the most common symptomatic primary immunodeficiency, present mainly in adults. There is a failure of B cells to develop and differentiate into plasma cells; at consequent a reduction of the production of one or more isotypes of antibody can also ...
Gallego, Claudia, González-Díaz, Sandra, del Carmen Zarate, Maria, Arias-Cruz, Alfredo, Garcia-Calderin, Diego, Yanneth Mejia Salas, Karla, Calva, Maricruz, Alfredo Dominguez Sansores, Luis   +7 more
openaire   +1 more source

Analysis of families with common variable immunodeficiency (CVID) and IgA deficiency suggests linkage of CVID to chromosome 16q [PDF]

Human Genetics, 2005
Common variable immunodeficiency (CVID) is an antibody deficiency syndrome that often co-occurs in families with selective IgA deficiency (IgAD). Vorechovský et al. (Am J Hum Genet 64:1096-1109, 1999; J Immunol 164:4408-4416, 2000) ascertained and genotyped 101 multiplex IgAD families and used them to identify and fine map the IGAD1 locus on chromosome
SCHAFFER AA, PFANNSTIEL J, WEBSTER ADB, PLEBANI, Alessandro, HAMMARSTROM L, GRIMBACHER B.   +5 more
openaire   +4 more sources

Investigating pulmonary and non-infectious complications in common variable immunodeficiency disorders: a UK national multi-centre study

Frontiers in Immunology
BackgroundCommon Variable Immunodeficiency Disorders (CVID) encompass a spectrum of immunodeficiency characterised by recurrent infections and diverse non-infectious complications (NICs).
Heba M. Bintalib, Heba M. Bintalib, Heba M. Bintalib, Sofia Grigoriadou, Smita Y. Patel, Leman Mutlu, Kavitha Sooriyakumar, Prashantha Vaitla, Elizabeth McDermott, Elizabeth Drewe, Cathal Steele, Manisha Ahuja, Tomaz Garcez, Mark Gompels, Alexandros Grammatikos, Archana Herwadkar, Rehana Ayub, Neil Halliday, Neil Halliday, Siobhan O. Burns, Siobhan O. Burns, John R. Hurst, Sarah Goddard   +22 more
doaj   +1 more source

Bronchoalveolar Lavage Fluid Reflects a TH1-CD21low B-Cell Interaction in CVID-Related Interstitial Lung Disease

Frontiers in Immunology, 2021
BackgroundAbout 20% of patients with common variable immunodeficiency (CVID) suffer from interstitial lung disease (ILD) as part of a systemic immune dysregulation.
David Friedmann, David Friedmann, David Friedmann, Susanne Unger, Susanne Unger, Susanne Unger, Baerbel Keller, Baerbel Keller, Mirzokhid Rakhmanov, Mirzokhid Rakhmanov, Mirzokhid Rakhmanov, Sigune Goldacker, Sigune Goldacker, Gernot Zissel, Björn C. Frye, Jonas C. Schupp, Jonas C. Schupp, Antje Prasse, Antje Prasse, Klaus Warnatz, Klaus Warnatz   +20 more
doaj   +1 more source

Electrocardiographic Alterations in Patients with Common Variable Immune Deficiency

İstanbul Medical Journal, 2020
Introduction:Common variable immunodeficiency (CVID) is the most heterogeneous group among the antibody deficiency syndromes, but its effects on the cardiovascular system have not yet been clearly identified.
Yakup Alsancak, Fatih Çölkesen
doaj   +1 more source

COVID‐19 infection in CVID patients: What we know so far

Immunity, Inflammation and Disease, 2021
Introduction In patients with common variable immunodeficiency (CVID), immunological response is compromised. Knowledge about COVID‐19 in CVID patients is sparse. We, here, synthesize current research addressing the level of threat COVID‐19 poses to CVID
Niels Weifenbach, Alisha Jung, Stefan Lötters   +2 more
doaj   +1 more source

Clinical Associations of Biallelic and Monoallelic TNFRSF13B Variants in Italian Primary Antibody Deficiency Syndromes

Journal of Immunology Research, 2016
We assessed the prevalence of TNFRSF13B mutations and the clinical correlates in an Italian cohort of 189 CVID, 67 IgAD patients, and 330 healthy controls to substantiate the role of TACI genetic testing in diagnostic workup.
Federica Pulvirenti, Roberta Zuntini, Cinzia Milito, Fernando Specchia, Giuseppe Spadaro, Maria Giovanna Danieli, Andrea Pession, Isabella Quinti, Simona Ferrari   +8 more
doaj   +1 more source

Cellular immunity in COVID-19 and other infections in Common variable immunodeficiency

Frontiers in Immunology, 2023
COVID-19 has shed light on the role of cellular immunity in the absence of humoral response in different patient groups. Common variable immunodeficiency (CVID) is characterized by impaired humoral immunity but also an underlying T-cell dysregulation ...
Ragnhild Øye Løken, Børre Fevang, Børre Fevang   +2 more
doaj   +1 more source

OBIČNA VARIJABILNA IMUNODEFICIJENCIJA (CVID)

SCRIPTA PEDIATRICA, 2018
Obična varijabilna imunodeficijencija (CVID) je primarni poremećaj imuniteta koga karakteriše smanjena sposobnostproizvodnje imunoglobulina. CVID ima incidenciju od 1:10.000 do 1: 200.000 (odnos muškog i ženskog polaje 1:1) i obično se javlja i dijagnostikuje iza desete godine života.
Želimir Erić, Biljana Đurđević-Banjac   +1 more
openaire   +2 more sources

Functional Defects in the NFκB pathway in Common Variable Immunodeficiency

Journal of Human Immunity
Common variable Immunodeficiency (CVID) is a heterogeneous immunodeficiency characterized by hypogammaglobulinemia and immune dysregulation. In up to 30% of cases, there is a monogenic defect, with a fraction of these familial. The majority, however, are
Terrence T.J. Hunter, Ioasaf Karafotias, David Fear, Mark Peakman, Mohammad A.A. Ibrahim   +4 more
doaj   +1 more source