Results 101 to 110 of about 21,433 (201)

LPS increases Cx43 expression.

open access: yes, 2014
HPAECs were treated with LPS (200 ng/mL) for 6 hr or 24 hr and collected for Western Blot or qRT-PCR analyses. A.) A representative Western blot is shown.
Anna A. Birukova (333901)   +3 more
core   +1 more source

Age‐ and sex‐specific modulation of human cardiac electrophysiology by doxorubicin

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend DOX differentially impacts cardiac electrophysiology based on sex and age. Sex differences were primarily observed among younger hearts, where action potential duration (APD) prolongation was observed in females, but not in males. Created using BioRender. George, S. (2026) https://BioRender.com/wresf1k Abstract Acute doxorubicin (
Sharon A. George   +5 more
wiley   +1 more source

Interaction between Cx43 and N-Cad proteins in human LA.

open access: yes, 2014
A. Representative double immunostaining image of Cx43 (green) and N-Cad (red). B-E. Enlarged images from a cropped area of image A including the Cx43/N-Cad overlay image (B), N-Cad (red; C), N-Cad pixel-by-pixel matched Cx43 signals (D), and non-N-Cad co-
Justin K. Thomson (611986)   +5 more
core   +1 more source

The proteasome regulates the interaction between Cx43 and ZO-1 [PDF]

open access: yes, 2007
Gap junction (GJ) intercellular communication (GJIC) is vital to ensure proper cell and tissue function. GJ are multimeric structures composed of proteins called connexins. Modifications on stability or subcellular distribution of connexins have a direct
Henrique Girao   +3 more
core   +1 more source

Immunoblot analysis of hippocampal lysates for Cre and Cx43 protein indicates loss of Cx43 expression in the absence of Cre protein.

open access: yes, 2013
In Cx43fl/del mice (green box), immunoreactivity for Cx43 is reduced by about 50% compared to Cx43fl/fl mice. Immunoreactivity for the full length Cx43 is completely lost in Cx43K258Stop/del mice (red box).
Bernd K. Fleischmann (107008)   +8 more
core   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

open access: yesBiological Reviews, Volume 101, Issue 5, Page 2265-2278, October 2026.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido   +2 more
wiley   +1 more source

Together and apart: inhibition of DNA synthesis by connexin-43 and its relationship to transforming growth factor-beta

open access: yesFrontiers in Pharmacology, 2013
The membrane and channel protein Connexin-43 (Cx43), as well as the cytokine transforming growth factor (TGF) beta, suppress proliferative growth in cardiomyocytes and other cell types.
Maya Madhumathy Jeyaraman   +2 more
doaj   +1 more source

Frozen in Place: Proximity Labeling Maps Glial Interactomes Across Cell States

open access: yesGlia, Volume 74, Issue 10, October 2026.
Proximity labeling enables cell‐type‐specific and spatially resolved mapping of glial protein networks. Proximity labeling approaches provide insights into glial function under physiological and pathological conditions. ABSTRACT Glial cells, including radial glia, oligodendrocyte precursor cells (OPCs), oligodendrocytes, astrocytes, and microglia, are ...
João Baltar   +3 more
wiley   +1 more source

Schematic diagram illustrating Cx43 hemichannel-mediated self-regulation of Cx43 under the stimulation of Cd2+.

open access: yes, 2013
Induction of oxidative stress and depletion of GSH by Cd2+ results in the opening of Cx43-hemichannels, leading to the efflux of the major antioxidant GSH.
Kun Gao (161056)   +7 more
core   +1 more source

Do Stimulants Promote Arrhythmic Risk: Insights From a Human‐Induced Pluripotent Stem Cell‐Derived Cardiomyocyte Model

open access: yesJournal of Arrhythmia, Volume 42, Issue 5, October 2026.
At clinically relevant plasma concentrations, stimulant medications produced minimal effects on conduction velocity but modulated automaticity and repolarization in a hiPSC‐derived cardiomyocyte (hiPSC‐CM) model. These findings provide a foundation for future investigations of stimulant‐associated cardiac safety and support the utility of hiPSC‐CM ...
Alia Arslanova   +5 more
wiley   +1 more source

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