BACKGROUND AND AIMS: Recruitment of leukocytes in the tissue microvasculature is considered to be a rate-limiting step in ischemia-reperfusion (I/R)-induced inflammation. The objective of this study was to examine the role of mast cells in CXC-chemokine-
Yusheng Wang +14 more
core +1 more source
Development of chemokine network inhibitors using combinatorial saturation mutagenesis
Targeting chemokine-driven inflammation has been elusive due to redundant pathways constituting chemokine-immune cell networks. Tick evasins overcome redundant pathways by broadly targeting either CC or CXC-chemokine classes.
Jhanna Kryukova +7 more
doaj +1 more source
Design, Synthesis, and Application of Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the CXC Chemokine Receptor 2. [PDF]
Casella BM +7 more
europepmc +1 more source
The role of interleukin 22 and non-ELR-CXC chemokines in human carotid plaque [PDF]
Objective: Inflammation plays an important role in atherogenesis, especially in plaque destabilisation. IL-22 enhances the innate immunity of tissue cells, favours the anti-microbial defence and protects tissue from damage.
Xia, Qiong
core
Bioinformatics Analysis of Prognostic Significance and Immune Characteristics of CXC Chemokine Family in Patients with Lung Adenocarcinoma. [PDF]
Bian D, Chen Y.
europepmc +1 more source
Loss of CXC-Chemokine Receptor 1 Expression in Chorioamnionitis Is Associated with Adverse Perinatal Outcomes. [PDF]
Wong YP +12 more
europepmc +1 more source
Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration. [PDF]
Park C +5 more
europepmc +1 more source
CXC chemokine ligand-10 promotes the accumulation of monocyte-like myeloid-derived suppressor cells by activating p38 MAPK signaling under tumor conditions. [PDF]
Sun Y +5 more
europepmc +1 more source
Hypoxia-induced CXC chemokine ligand 14 expression drives protumorigenic effects through activation of insulin-like growth factor-1 receptor signaling in glioblastoma. [PDF]
Wei ST +8 more
europepmc +1 more source
Molecular basis of CXC chemokine receptor 3 ligand multispecificity. [PDF]
Bouyssou A +15 more
europepmc +1 more source

