Results 81 to 90 of about 88,618 (194)

CXC chemokine receptors in the central nervous system: Role in cerebellar neuromodulation and development

, 2002
Chemokines and their receptors are constitutively present in the central nervous system (CNS), expressed in neurons and glial cells. Much evidence suggests that, beyond their involvement in neuroinflammation, these proteins play a role in ...
RAGOZZINO, Davide Antonio
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Chemokine CXCL1 is responsible for cocaine‐induced reward in mice

Neuropsychopharmacology Reports, 2018
Aim We have previously demonstrated that upregulation of CC chemokines through dopamine receptor signaling in the prefrontal cortex (PFC) underlies methamphetamine (Meth)‐induced reward. Given the common pharmacological property of Meth and cocaine (Coca)
Fumihiro Saika, Shinsuke Matsuzaki, Daichi Kobayashi, Norikazu Kiguchi, Shiroh Kishioka   +4 more
doaj   +1 more source

ELR CXC chemokine expression in benign and malignant colorectal conditions-4

, 2011
per mg total protein in CRC and CRA tissues and unaffected neighbor tissues, respectively. The data are expressed as mean +/- standard error of the mean (SEM), * < 0.05, ** < 0.001, = 48 and 30, respectively.Copyright information:Taken from "ELR+ CXC ...
Claudia Rubie (55165), Mathias Wagner (55167), Brigitte Brittner (55170), Stefan Gräber (55169), Vilma Oliveira Frick (55166), Jochen Schuld (55168), Rainer M Bohle (5493), Martin K Schilling (55171)   +7 more
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Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487. [PDF]

Cell Discov, 2023
Jiao H, Pang B, Chiang YC, Chen Q, Pan Q, Ren R, Hu H.   +6 more
europepmc   +1 more source

Chemotherapy-Induced CXC-Chemokine/CXC-Chemokine Receptor Signaling in Metastatic Prostate Cancer Cells Confers Resistance to Oxaliplatin through Potentiation of Nuclear Factor-κB Transcription and Evasion of Apoptosis

, 2008
Constitutive activation of nuclear factor (NF)-kappa B is linked with the intrinsic resistance of androgen-independent prostate cancer (AIPC) to cytotoxic chemotherapy.
Oladipo, Olabode, Purcell, Colin, Wilson, Richard H., Seaton, Angela, O'Sullivan, Joe M.; id_orcid, Johnston, Patrick G., Waugh, David J. J., Wilson, Catherine, Maxwell, Pamela J.; id_orcid   +8 more
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Structural basis of CXC chemokine receptor 1 ligand binding and activation. [PDF]

Nat Commun, 2023
Ishimoto N, Park JH, Kawakami K, Tajiri M, Mizutani K, Akashi S, Tame JRH, Inoue A, Park SY.   +8 more
europepmc   +1 more source

The expression and prognostic impact of CXC-chemokines in stage II and III colorectal cancer epithelial and stromal tissue

, 2011
BACKGROUND: The CXC-chemokine expression is linked with colorectal cancer (CRC) progression but their significance in resected CRC is unclear.
P J Maxwell, M Stevenson, O'Grady, PJ, Purcell, Colin, Wilson, Richard, Waugh, David, A O'Grady, Oladipo, O., C Purcell, C Wilson, Johnston, Patrick, O Oladipo, Conlon, Mairead, Wilson, Catherine, P G Johnston, S Conlon, Stevenson, Michael, E W Kay, R H Wilson, Kay, E.W., D J J Waugh, Conlon, S, Oladipo, O, Wilson, R H, Kay, E W, Johnston, P G, O'Grady, A, Maxwell, P J, Purcell, C, Stevenson, M, Waugh, D J J, Maxwell, Pamela; id_orcid, Wilson, C   +32 more
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ELR CXC chemokine expression in benign and malignant colorectal conditions-7

, 2011
< 0.05, ** < 0.001, = 30 (CRA), 48 (CRC) and 16 (CRLM), respectively. Fold increase above 1 indicates CXCR2 overexpression in CRA, CRC and CRLM tissues related to unaffected neighbor tissues, respectively.Copyright information:Taken from "ELR+ CXC ...
Claudia Rubie (55165), Mathias Wagner (55167), Brigitte Brittner (55170), Stefan Gräber (55169), Vilma Oliveira Frick (55166), Jochen Schuld (55168), Rainer M Bohle (5493), Martin K Schilling (55171)   +7 more
core   +1 more source

C-X-C motif chemokine ligand 12—C-X-C chemokine receptor type 4 signaling axis in cancer and the development of chemotherapeutic molecules

Tzu Chi Medical Journal
Chemokines are small, secreted cytokines crucial in the regulation of a variety of cell functions. The binding of chemokine C-X-C motif chemokine ligand 12 (CXCL12) (stromal cell-derived factor 1) to a G-protein-coupled receptor C-X-C chemokine receptor ...
Jui-Hung Yen, Chun-Chun Chang, Hao-Jen Hsu, Chin-Hao Yang, Hemalatha Mani, Je-Wen Liou   +5 more
doaj   +1 more source

Chemokine stromal cell–derived factor 1α activates basophils by means of CXCR4

, 2000
The CXC chemokine receptor 4 (CXCR4) is predominantly expressed on inactivated naive T lymphocytes, B lymphocytes, dendritic cells, and endothelial cells.
Henrik H. Jacobi, Jing, C, Reimert, C M, Poulsen, Lars K., Jacobi, H H, Quan, S, Tan Jinquan, Skov, P S, Lars K. Poulsen, Steen Dissing, Claus M. Reimert, Dissing, S, Chen Jing, Sha Quan, Jinquan, T, Per S. Skov   +15 more
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