Streptococcal M1 Protein-Provoked CXC Chemokine Formation, Neutrophil Recruitment and Lung Damage Are Regulated by Rho-Kinase Signaling. [PDF]
, 2012 Streptococcal toxic shock syndrome is frequently caused by Streptococcus pyogenes of the M1 serotype. The aim of this study was to determine the role of Ras-homologous (Rho)-kinase signaling in M1 protein-provoked lung damage.
Thorlacius, Henrik +13 more
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Chemokine Receptors and Phagocyte Biology in Zebrafish. [PDF]
, 2020 Phagocytes are highly motile immune cells that ingest and clear microbial invaders, harmful substances, and dying cells. Their function is critically dependent on the expression of chemokine receptors, a class of G-protein-coupled receptors (GPCRs ...
Sommer, F. +6 more
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International Journal of General Medicine, 2022 Kun Wang, Rongyang Li, Yu Zhang, Weifeng Qi, Tao Fang, Weiming Yue, Hui Tian Department of Thoracic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, People’s Republic of ChinaCorrespondence: Hui Tian ...
Wang K +6 more
doaj
BMC Immunology, 2008 Background The ELR+CXC chemokines are multifunctional mediators that are mainly responsible for the recruitment of leucocytes to sites of inflammation and infection.
Kezhi Xing +4 more
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2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors
, 2005 The CXC chemokine CXCL8/IL-8 plays a major role in the activation and recruitment of polymorphonuclear (PMN) cells at inflammatory sites. CXCL8 activates PMNs by binding the seven-transmembrane (7-TM) G-protein-coupled receptors CXC chemokine receptor 1 (
V. Berdini +17 more
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Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]
, 2004 Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Anders, Hans-Joachim +3 more
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Regulation of Expression of CXC Chemokines in Cultured Hepatocytes [PDF]
Iranian Journal of Public Health, 2005 Chemokines are low molecular weight proteins (8-17 kDa). They are classified in four distinct groups as CXC, CC, CX3C and C. Depending on the presence or absence of a motif called ELR (Arg-Leu-Glu) before the first cysteine residue in their structure ...
GhH Hassanshahiraviz, AJ Dickson
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The role of the chemokine receptor CXCR4 in infection with feline immunodeficiency virus [PDF]
, 1999 Infection with feline immunodeficiency virus (FIV) leads to the development of a disease state similar to AIDS in man. Recent studies have identified the chemokine receptor CXCR4 as the major receptor for cell culture-adapted strains of FIV, suggesting ...
Hosie, M.J. +3 more
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Corneal and Conjunctival Fibroblasts Are Major Sources of Eosinophil-Recruiting Chemokines
Allergology International, 2009 Background: Differential expression of chemokine genes were investigated in various types of ocular surface cells. Methods: Primary cultures of human corneal epithelial cells (n = 3), corneal fibroblasts (n = 2), conjunctival epithelial cells (n = 2) and
Kazumi Fukagawa +9 more
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ELR CXC chemokine expression in benign and malignant colorectal conditions-1
, 2011 < 0.05, ** < 0.001, = 23 and 25, respectively. Fold increase above 1 indicates chemokine overexpression in CRC tissues related to unaffected neighbor tissues, respectively.
Claudia Rubie (55165) +7 more
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