Results 91 to 100 of about 88,618 (194)

Anti-HIV Activity and Resistance Profile of the CXC Chemokine Receptor 4 Antagonist POL3026 □ S [PDF]

, 2020
We have studied the mechanism of action of Arg*-Arg-Nal 2 -Cys(1ϫ)-Tyr-Gln-Lys-(D-Pro)-Pro-Tyr-Arg-Cit-Cys(1ϫ)-ArgGly-(D-Pro)* (POL3026), a novel specific ␤-hairpin mimetic CXC chemokine receptor (CXCR)4 antagonist.
J W V, F O G, S D, ( B R
core  

CXC chemokine receptor 4 (CXCR4) blockade in cancer treatment. [PDF]

J Cancer Res Clin Oncol, 2023
Bao S, Darvishi M, H Amin A, Al-Haideri MT, Patra I, Kashikova K, Ahmad I, Alsaikhan F, Al-Qaim ZH, Al-Gazally ME, Kiasari BA, Tavakoli-Far B, Sidikov AA, Mustafa YF, Akhavan-Sigari R.   +14 more
europepmc   +1 more source

Keratinocyte cytokine and chemokine receptors

, 2007
Chemokines are a superfamily of small, secreted proteins that regulate cell traffic in homeostatic and inflammatory conditions. Keratinocytes synthesize many chemokines, including members of the CC and CXC subfamilies, such as regulated on activation of ...
Wolf, Ronni, Antonov, Meltem, Dolar, Neslihan, Tuezuen, Yalçın, Tuezuen, YALÇIN   +4 more
core   +1 more source

Atypical Chemokine Receptor 3 "Senses" CXC Chemokine Receptor 4 Activation Through GPCR Kinase Phosphorylation. [PDF]

Mol Pharmacol, 2023
Schafer CT, Chen Q, Tesmer JJG, Handel TM.   +3 more
europepmc   +1 more source

Multiple specificity binders of CXC chemokines and uses thereof

, 2018
The present disclosure provides for fusion proteins comprising multispecific variable regions that bind more than one ELR+ CXC chemokine. The disclosure also provides methods of treating or preventing a condition associated with an abnormal immune ...
Andrew David Luster, Angelini Alessandro, Karl Dane Wittrup   +2 more
core  

A review of the pleiotropic actions of the IFN-inducible CXC chemokine receptor 3 ligands in the synovial microenvironment. [PDF]

Cell Mol Life Sci, 2023
Dillemans L, De Somer L, Neerinckx B, Proost P.   +3 more
europepmc   +1 more source

STAT3-dependent CXC chemokine formation and neutrophil migration in streptococcal M1 protein-induced acute lung inflammation

, 2015
Streptococcus pyogenes cause infections ranging from mild pharyngitis to severe streptococcal toxic shock syndrome (STSS). The M1 serotype of Streptococcus pyogenes is most frequently associated with STSS. Herein, it was hypothesized that STAT3 signaling
Rundk Hwaiz, Songen Zhang, Lingtao Luo, Heiko Herwald, Henrik Thorlacius, Thorlacius, Henrik,, Zhang, Songen,, Lund University., Herwald, Heiko,, Luo, Ling Tao,, Hwaiz, Rundk,   +10 more
core   +1 more source

The Y44 residue point mutation in CXCL14 reveals the significance of CXCL14 protein stability in anti-tumor activity

Oncologie
CXCL14, a member of the CXC chemokine family, plays a significant role in tumor development, progression, and metastasis, making it a potential target for cancer diagnosis and treatment.
Kamal Shah, Ullah Najeeb, Kong Xianglin, Amanullah Amanullah, Dai Ao, Kamal Mohammad Amjad, Deng Cheng, Shanshan Lai   +7 more
doaj   +1 more source

Systematic Analysis of CXC Chemokine-Vascular Endothelial Growth Factor A Network in Colonic Adenocarcinoma from the Perspective of Angiogenesis. [PDF]

Biomed Res Int, 2022
Situ Y, Lu X, Cui Y, Xu Q, Deng L, Lin H, Shao Z, Chen J.   +7 more
europepmc   +1 more source

Generation and functional significance of CXC chemokines for neutrophil-induced liver injury during endotoxemia

, 2005
The hypothesis that the neutrophil chemoattractant CXC chemokines KC and macrophage inflammatory protein-2 (MIP-2) are involved in neutrophil transmigration and liver injury was tested in C3Heb/FeJ mice treated with galactosamine (Gal, 700 mg/kg ...
Bajt, Mary Lynn, Anwar Farhood, Robert B. Dorman, Mary Lynn Bajt, Farhood, Anwar, Hartmut Jaeschke, Gujral, Jaspreet S., Dorman, Robert B., Jaeschke, Hartmut, Jaspreet S. Gujral   +9 more
core   +1 more source